Substance profile
Dioxathion
Dioxathion is a tan liquid.
01 · Identification
What Dioxathion is
Dioxathion is a tan liquid. Its molecular formula is C12H26O6P2S4 and its molecular weight is 456.5 g/mol. It melts at -20 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Dioxathion identifiers and molecular data
Dioxathion CAS number and EC number
Dioxathion molecular formula and molecular weight
Other names for Dioxathion
- dioxathion (ISO)
- 1,4-dioxan-2,3-diyl-O,O,O',O'-tetraethyl di(phosphorodithioate)
03 · GHS classification
Dioxathion hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Dioxathion pictograms and signal word
Dioxathion hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 1 or 2 | H300 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 3 | H311 | GHS06 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 1 or 2 | H330 | GHS06 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Dioxathion hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H330 | Fatal if inhaled. |
| H300 | Fatal if swallowed. |
| H311 | Toxic in contact with skin. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Dioxathion. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Dioxathion
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Dioxathion issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Dioxathion precautionary statements
CLP Annex VI assigns 13 precautionary statements to Dioxathion. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Dioxathion name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | диоксатион (ISO) 1,4-диоксан-2,3-диил- О , О , О ′, О ′-тетраетилов ди(фосфородитиоат) |
| Spanish español | Dioxatión (ISO) di(fosforoditioato) de 1,4-dioxano-2,3-diilo y O , O , O ', O '- tetraetilo |
| Czech čeština | dioxathion (ISO) S, S' -(1,4-dioxan-2,3-diyl)- O, O,O',O' -tetraethylbis(fosforodithioát) |
| Danish dansk | dioxathion (ISO) 1,4-dioxan-2,3-diyl- O, O,O' , O' -tetraethyldi (dithiophosphat) |
| German Deutsch | Dioxathion (ISO) 1,4-Dioxan-2,3-diyl- O , O , O ', O '-tetraethyldi(phosphorodithioat) |
| Estonian eesti | dioksatioon (ISO) 1,4-dioksaan-2,3-diüül- O , O , O ', O '-tetraetüüldi(fosforoditioaat) |
| Greek ελληνικά | dioxathion (διοξαθείο) (ISO) δι(διθειοφωσφορικός 1,4-διοξαν-2,3-διυλ- O , O , O ′, O ′-τετρααιθυλεστέρας |
| English English | dioxathion (ISO) 1,4-dioxan-2,3-diyl- O , O , O ', O '-tetraethyl di(phosphorodithioate) |
| French français | dioxathion (ISO) di(phosphorodithioate) de 1,4-dioxan-2,3-diyl- O, O,O',O' -tétraéthyle |
| Croatian hrvatski | dioksation (ISO) 1,4-dioksan-2,3-diil- O , O , O ', O '-tetraetil-di(fosforoditioat) |
| Italian italiano | dioxation (ISO) di(ditiofosfato) di 1,4-diossan-2,3-diile e O, O,O',O'-tetraetile |
| Latvian latviešu | dioksations (ISO) 1,4-dioksān-2,3-diil- O , O , O ', O '-tetraetildi(fosforditioāts) |
| Lithuanian lietuvių | dioksationas (ISO) 1,4-dioksan-2,3-diil- O , O , O ', O '-tetraetildi(ditiofosfatas) |
| Hungarian magyar | dioxation (ISO) 1,4-dioxán-2,3-diil- O, O,O',O' -tetraetil-di(ditiofoszfát) |
| Maltese Malti | diossatijon (ISO) di(fosforoditijoat) ta’ 1,4-diossan-2,3-diil- O , O , O ', O '-tetraetil |
| Dutch Nederlands | dioxathion (ISO) 1,4-dioxaan-2,3-diyl- O , O , O' , O' -tetraëthyldi(dithiofosfaat) |
| Polish polski | dioksation (ISO) bis(ditiofosforan) S , S '-1,4-dioksan-2,3-diylu- O , O , O ', O '-tetraetylu |
| Portuguese português | dioxatião (ISO) di(ditiofosfato) de 1,4-dioxan-2,3-diilo e de O , O , O ', O '-tetraetilo |
| Romanian română | dioxation (ISO) bis(ditiofosfat) de 1,4- dioxan-2,3-diil și de O, O,O',O' -tetraetil |
| Slovak slovenčina | dioxatión (ISO) S, S ’-(1,4-dioxán-2,3-diyl)- O, O,O',O '- tetraetyl-bis(fosforoditioát) |
| Slovenian slovenščina | dioksation (ISO) 1,4-dioksan-2,3-diil- O , O , O ', O '-tetraetil di(fosforoditioat) |
| Finnish suomi | dioksationi (ISO) 1,4-dioksaani-2,3-diyyli- O, O,O’,O’ -tetraetyylidi(fosforoditioaatti) |
| Swedish svenska | dioxation (ISO) 1,4-dioxan-2,3-diyl- O , O , O ', O '-tetraetyldi(fosforditioat) |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Dioxathion GHS label elements
Everything CLP Annex VI fixes for Dioxathion, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Dioxathion
- Fatal if inhaled.
- Fatal if swallowed.
- Toxic in contact with skin.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF INHALED:
- Immediately call a POISON CENTER/doctor/…
- Rinse mouth.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Dioxathion in the GHS label constructor →
07 · Health hazards
Dioxathion health hazards and exposure limits
Dioxathion hazard summary
Inhalation of high concentrations may cause CNS effects; Cholinesterase inhibitor; [ICSC] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Dioxathion carcinogenicity classification
Under the conditions of this bioassay, dietary administration of dioxathion was not carcinogenic in Osborne-Mendel rats or B6C3F1 mice.
Source: US National Toxicology Program · TR-125: Bioassay of Dioxathion for Possible Carcinogenicity (CASRN 78-34-2) (1978 )
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
Dioxathion occupational exposure limits
| Limit | Value | Source |
|---|---|---|
| PEL | none See Appendix G | The National Institute for Occupational Safety and Health (NIOSH) |
| REL | 0.2 mg/m³ | Occupational Safety and Health Administration (OSHA) |
| REL | TWA 0.2 mg/m3 [skin] | The National Institute for Occupational Safety and Health (NIOSH) |
| IDLH | N.D. | The National Institute for Occupational Safety and Health (NIOSH) |
These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.
08 · Physical and chemical properties
Dioxathion properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Dioxathion boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 63.89 °C (147 °F) | range, midpoint shown, at 0.5 mmHg (reduced pressure) | CAMEO |
Dioxathion melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -20 °C (-4 °F) | HSDB |
Dioxathion density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.257 g/cm³ | at 26 °C | HSDB |
| 1.26 g/cm³ | at 26 °C | ICSC |
Dioxathion solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | PRACTICALLY INSOL IN WATER; PARTLY SOL IN HEXANE | HSDB | |
| 10 G/KG HEXANE, KEROSENE | HSDB | ||
| SOL IN AROMATIC HYDROCARBONS, ETHERS, ESTERS, & KETONES | HSDB |
Dioxathion vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 17.8 mmHg | OSHA | |
| 17.8 mmHg | at 25 °C | CAMEO | |
| 9e-8 mmHg | Haz-Map |
Dioxathion lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | Noncombustible Liquid | NIOSH |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
Dioxathion fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Dioxathion fire potential
NON-FLAMMABLE
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
Dioxathion storage and handling
Dioxathion safe storage
Separated from food and feedstuffs. Dry. Keep in a well-ventilated room. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Dioxathion storage conditions
STORAGE: ...MUST BE STORED IN ITS SEALED ORIGINAL CONTAINERS, IN WELL-AIRED, FRESH & DRY STOREHOUSES OR IN SHADED & POSSIBLY WELL-AIRED PLACES. IT IS RECOMMENDED THAT THE PRODUCT'S TEMP...NOT EXCEED 25-30 °C, & KEEP...AWAY FROM SOURCES OF HEAT, FREE FLAMES OR SPARK-GENERATING EQUIPMENT. CONTAINERS MUST BE STACKED IN SUCH A WAY AS TO PERMIT FREE CIRCULATION OF AIR...AT BOTTOM & INSIDE OF PILES. STORAGE AREAS MUST BE LOCATED AT SUITABLE DISTANCE FROM INHABITED BUILDINGS, ANIMAL SHELTERS, & FOOD STORES; MOREOVER, THEY MUST BE INACCESSIBLE TO UNAUTHORIZED PERSONS, CHILDREN, & DOMESTIC ANIMALS. /DIMETHOATE/
Source: Hazardous Substances Data Bank (HSDB)
Dioxathion incompatible materials
Alkalis, iron or tin surfaces, heat.
Source: Hazardous Substances Data Bank (HSDB)
Dioxathion reactivity
DIOXATHION is heat sensitive. This chemical may react with iron or tin surfaces. It may be hydrolyzed by strong acids or alkalis. (NTP, 1992). Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Dioxathion in the storage compatibility matrix →
11 · Questions
Dioxathion — frequently asked questions
What is the CAS number of Dioxathion?
The CAS number of Dioxathion is 78-34-2. Its EC number is 201-107-7.
What is the chemical formula of Dioxathion?
The molecular formula of Dioxathion is C12H26O6P2S4 and its molecular weight is 456.5 g/mol.
What does a Dioxathion label have to show?
Under CLP Annex VI the label for Dioxathion carries the pictograms Skull and crossbones and Environment and the signal word is Danger.
Is Dioxathion flammable?
CLP Annex VI assigns Dioxathion no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Dioxathion a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Dioxathion. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the exposure limit for Dioxathion?
The US occupational exposure limit reported for Dioxathion is none See Appendix G (The National Institute for Occupational Safety and Health (NIOSH)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.
What is the boiling point of Dioxathion?
The boiling point reported for Dioxathion is 63.89 °C (147 °F), range, midpoint shown, at 0.5 mmHg (reduced pressure) (CAMEO).
What is the melting point of Dioxathion?
The melting point reported for Dioxathion is -20 °C (-4 °F) (HSDB).
How should Dioxathion be stored?
STORAGE: ...MUST BE STORED IN ITS SEALED ORIGINAL CONTAINERS, IN WELL-AIRED, FRESH & DRY STOREHOUSES OR IN SHADED & POSSIBLY WELL-AIRED PLACES. IT IS RECOMMENDED THAT THE PRODUCT'S TEMP...NOT EXCEED 25-30 °C, & KEEP...AWAY FROM SOURCES OF HEAT, FREE FLAMES OR SPARK-GENERATING EQUIPMENT. CONTAINERS MUST BE STACKED IN SUCH A WAY AS TO PERMIT FREE CIRCULATION OF AIR...AT BOTTOM & INSIDE OF PILES. STORAGE AREAS MUST BE LOCATED AT SUITABLE DISTANCE FROM INHABITED BUILDINGS, ANIMAL SHELTERS, & FOOD STORES; MOREOVER, THEY MUST BE INACCESSIBLE TO UNAUTHORIZED PERSONS, CHILDREN, & DOMESTIC ANIMALS. /DIMETHOATE/ (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Dioxathion
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