Substance profile
Esfenvalerate
Esfenvalerate is a white crystalline solid.
01 · Identification
What Esfenvalerate is
Esfenvalerate is a white crystalline solid. Its molecular formula is C25H22ClNO3 and its molecular weight is 419.9 g/mol. It boils at 159 °C, melts at 59.6 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Esfenvalerate identifiers and molecular data
Esfenvalerate CAS number and EC number
Esfenvalerate molecular formula and molecular weight
Other names for Esfenvalerate
- esfenvalerate (ISO)
- (S)-α-cyano- 3-phenoxybenzyl-(S)- 2-(4-chlorophenyl)- 3-methylbutyrate
03 · GHS classification
Esfenvalerate hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Esfenvalerate pictograms and signal word
Esfenvalerate hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 3 | H301 | GHS06 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 3 | H331 | GHS06 |
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 1 | H370 | GHS08 |
| Specific target organ toxicity - repeated exposure GHS chapter 3.9 | Category 2 | H373 | GHS08 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Esfenvalerate hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H331 | Toxic if inhaled. |
| H301 | Toxic if swallowed. |
| H370 | Causes damage to organs <or state all organs affected, if known> <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H373 | May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H317 | May cause an allergic skin reaction. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Esfenvalerate. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Esfenvalerate
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Esfenvalerate issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Esfenvalerate precautionary statements
CLP Annex VI assigns 18 precautionary statements to Esfenvalerate. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Esfenvalerate name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | есфенвалерат (ISO) ( S )-3-фенокси-α-цианобензилов ( S )-3- метил-2-(4-хлорофенил)бутират |
| Spanish español | Esfenvalerato (ISO) ( S )-2-(4-clorofenil)-3-metilbutirato de ( S )-α-ciano-3-fenoxibencilo |
| Czech čeština | esfenvalerát (ISO) [( S )-(3-fenoxyfenyl)kyanmethyl]-( S )-2-(4-chlorfenyl)-3-methylbutanoát |
| Danish dansk | esfenvalerat (ISO) (S)-α-cyan-3-phenoxybenzyl-( S )-2-(4-chlorphenyl)-3-methylbutyrat |
| German Deutsch | Esfenvalerat (ISO) (S)-α-Cyan-3-phenoxybenzyl-( S )-2-(4-chlorphenyl)-3-methylbutyrat |
| Estonian eesti | esfenvaleraat (ISO) ( S )-α-tsüano-3-fenoksübensüül-( S )-2-(4-klorofenüül)-3-metüülbutüraat |
| Greek ελληνικά | esfenvalerate (εσφενοβαλεριανικό) (ISO) (S)-2-(4-χλωροφαινυλο)-3-μεθυλοβουτυρικό ( S )-α-κυανο-3-φαινοξυβενζύλιο |
| English English | esfenvalerate (ISO) (S)-α-cyano-3-phenoxybenzyl-( S )-2-(4-chlorophenyl)-3-methylbutyrate |
| French français | esfenvalérate (ISO) ( S )-α-cyano-3-phénoxybenzyl-( S )-2-(4-chlorophényl)-3-méthylbutyrate |
| Croatian hrvatski | esfenvalerat (ISO) (S)-α-cijano-3-fenoksibenzil-( S )-2-(4-klorofenil)-3-metilbutirat |
| Italian italiano | esfenvalerate (ISO) (S)-α-ciano-3-fenossibenzil-( S )-2-(4-clorofenil)-3-metilbutirrato |
| Latvian latviešu | esfenvalerāts (ISO) ( S )-α-ciān-3-fenoksibenzil-( S )-2-(4-hlorfenil)-3-metilbutirāts |
| Lithuanian lietuvių | esfenvaleratas (ISO) (S)-α-cian-3-fenoksibenzil-( S )-2-(4-chlorfenil)-3-metilbutiratas |
| Hungarian magyar | eszfenvalerát (ISO) (S)-α-ciano-3-fenoxibenzil-( S )-2-(4-klórfenil)-3-metilbutirát |
| Maltese Malti | esfenvalerat (ISO) (S)-α-ċjano-3-fenossibenżil-( S )-2-(4-klorofenil)-3-metilbutirat |
| Dutch Nederlands | esfenvaleraat (ISO) (S)-α-cyaan-3-fenoxybenzyl-( S )-2-(4-chloorfenyl)-3-methylbutyraat |
| Polish polski | esfenwalerat (ISO) (S)-α-cyjano-3-fenoksybenzylo-( S )-2-(4-chlorofenylo)-3-metylomaślan |
| Portuguese português | esfenvalerato (ISO) ( S )-2-(4-clorofenil)-3-metilbutirato de ( S )-α-ciano-3-fenoxibenzilo |
| Romanian română | esfenvalerat (ISO) ( S )-2-(4-clorofenil)-3-metilbutirat de (S)-α-ciano-3-fenoxibenzil |
| Slovak slovenčina | esfenvalerát (ISO), ( S )-[(3-fenoxyfenyl)-kyanometyl]-2( S )-2-(4-chlórfenyl)-3-metylbutanoát |
| Slovenian slovenščina | esfenvalerat (ISO) (S)-α-ciano-3-fenoksibenzil-( S )-2-(4-klorofenil)-3-metilbutirat |
| Finnish suomi | esfenvaleraatti (ISO) (S)-α-syano-3-fenoksibentsyyli-( S )-2-(4-kloorifenyyli)-3-metyylibutyraatti |
| Swedish svenska | esfenvalerat (ISO) (S)-α-cyano-3-fenoxibensyl-( S )-2-(4-klorfenyl)-3-metylbutyrat |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Esfenvalerate GHS label elements
Everything CLP Annex VI fixes for Esfenvalerate, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Esfenvalerate
- Toxic if inhaled.
- Toxic if swallowed.
- Causes damage to organs <or state all organs affected, if known> <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- May cause an allergic skin reaction.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Contaminated work clothing should not be allowed out of the workplace.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF INHALED:
- IF exposed or concerned:
- Immediately call a POISON CENTER/doctor/…
- Call a POISON CENTER/doctor/…
- Get medical advice/attention.
- Get medical advice/attention if you feel unwell.
- Rinse mouth.
- If skin irritation or rash occurs:
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Esfenvalerate in the GHS label constructor →
07 · Health hazards
Esfenvalerate health hazards and exposure limits
Esfenvalerate carcinogenicity classification
Cancer Classification: Group E Evidence of Non-carcinogenicity for Humans
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
Esfenvalerate properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Esfenvalerate boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 159 °C (318.2 °F) | range, midpoint shown | HSDB |
Esfenvalerate melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 59.6 °C (139.3 °F) | range, midpoint shown | HSDB |
| 59.5 °C (139.1 °F) | range, midpoint shown | ICSC |
Esfenvalerate density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.26 g/cm³ | HSDB | |
| 1.2 g/cm³ | ICSC |
Esfenvalerate solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | In acetone, chloroform, methanol >450, hexane 77 (all in g/L at 20 °C; distilled water <20 ug/L (all at 20 °C) | at 20 °C | HSDB |
| In xylene, acetone, chloroform, ethyl acetate, dimethylformamide, dimethyl sulfoxide >600, hexane 10-50, methanol 70-100 (all in g/kg, 25 °C) | at 25 °C | HSDB |
Esfenvalerate vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 1.5e-9 mmHg | at 25 °C | HSDB |
| Vapor pressure at 20 °C: negligible | at 20 °C | ICSC |
Esfenvalerate flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 256 °C (492.8 °F) | ICSC |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
Esfenvalerate fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Esfenvalerate fire potential
/Pyrethrins/ ... burn with difficulty. /Pyrethrins/
Source: Hazardous Substances Data Bank (HSDB)
Solubility
Solubility (1%): acetonitrile >60, chloroform >60, DMF >60, DMSO >60, ethyl acetate >60, acetone >60, ethyl cellosolve 40-50, n-hexane 1-5, kerosene <1, methanol 7-10, alpha-methylnaphthalene 50-60, xylene >60.
Source: HSDB
10 · Handling and storage
Esfenvalerate storage and handling
Esfenvalerate safe storage
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Keep in a well-ventilated room.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Esfenvalerate storage conditions
Store in original container.
Source: Hazardous Substances Data Bank (HSDB)
Esfenvalerate incompatible materials
Incompatibility: Strong oxidizers. /Pyrethrins/
Source: Hazardous Substances Data Bank (HSDB)
Planning storage for a mix of chemicals? Check Esfenvalerate in the storage compatibility matrix →
11 · Questions
Esfenvalerate — frequently asked questions
What is the CAS number of Esfenvalerate?
The CAS number of Esfenvalerate is 66230-04-4.
What is the chemical formula of Esfenvalerate?
The molecular formula of Esfenvalerate is C25H22ClNO3 and its molecular weight is 419.9 g/mol.
What does a Esfenvalerate label have to show?
Under CLP Annex VI the label for Esfenvalerate carries the pictograms Skull and crossbones, Health hazard and Environment and the signal word is Danger.
Is Esfenvalerate flammable?
CLP Annex VI assigns Esfenvalerate no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 256 °C (492.8 °F) (ICSC).
Is Esfenvalerate a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Esfenvalerate. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of Esfenvalerate?
The boiling point reported for Esfenvalerate is 159 °C (318.2 °F), range, midpoint shown (HSDB).
What is the melting point of Esfenvalerate?
The melting point reported for Esfenvalerate is 59.6 °C (139.3 °F), range, midpoint shown (HSDB).
How should Esfenvalerate be stored?
Store in original container. (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Esfenvalerate
Keep going: substances starting with E, or search the whole database by name, CAS number, pictogram or signal word.