Substance profile
Flocoumafen
Flocoumafen is an off-white solid.
01 · Identification
What Flocoumafen is
Flocoumafen is an off-white solid. Its molecular formula is C33H25F3O4 and its molecular weight is 542.5 g/mol. It melts at 186 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Flocoumafen identifiers and molecular data
Flocoumafen CAS number and EC number
Flocoumafen molecular formula and molecular weight
Other names for Flocoumafen
- flocoumafen (ISO)
- reaction mass of: cis-4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluoromethylbenzyloxy)phenyl)-1-naphthyl)coumarin and trans-4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluoromethylbenzyloxy)phenyl)-1-naphthyl)coumarin
03 · GHS classification
Flocoumafen hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Flocoumafen pictograms and signal word
Flocoumafen hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 1 or 2 | H300 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 1 or 2 | H310 | GHS06 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 1 or 2 | H330 | GHS06 |
| Specific target organ toxicity - repeated exposure GHS chapter 3.9 | Category 1 | H372 | GHS08 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Flocoumafen hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H360D | May damage the unborn child. |
| H330 | Fatal if inhaled. |
| H310 | Fatal in contact with skin. |
| H300 | Fatal if swallowed. |
| H372 | Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Flocoumafen. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Flocoumafen
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Flocoumafen issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Flocoumafen precautionary statements
CLP Annex VI assigns 14 precautionary statements to Flocoumafen. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Flocoumafen name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | флокумафен (ISO) реакционна маса от: цис -4-хидрокси-3-(1,2,3,4-тетрахидро-3-(4-(4-трифлуорометилбензилокси)фенил)-1-нафтил)кумарин и транс -4-хидрокси-3-(1,2,3,4-тетрахидро-3-(4-(4-трифлуорометилбензилокси)фенил)-1-нафтил)кумарин |
| Spanish español | flocumafén (ISO) masa de reacción de: cis -4-hidroxi-3-(1,2,3,4-tetrahidro-3-(4-(4-trifluorometilbenciloxi)fenil)-1-naftil)cumarina y trans -4-hidroxi-3-(1,2,3,4-tetrahidro-3-(4-(4-trifluorometilbenciloxi)fenil)-1-naftil)cumarina |
| Czech čeština | flokumafen (ISO) reakční směs cis -4-hydroxy-3-[3-(4{[4-(trifluormethyl)benzyl]oxy}fenyl)-1,2,3,4-tetrahydro-1-naftyl]-2 H -chromen-2-on a trans -4-hydroxy-3-[3-(4{[4-(trifluormethyl)benzyl]oxy}fenyl)-1,2,3,4-tetrahydro-1-naftyl]-2 H -chromen-2-on |
| Danish dansk | flocoumafen (ISO) reaktionsblanding af: cis-4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluormethylbenzyloxy)phenyl)-1-naphthyl)coumarin og trans-4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluormethylbenzyloxy)phenyl)-1-naphthyl)coumarin |
| German Deutsch | Flocoumafen (ISO) Reaktionsmasse aus: cis-4-Hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluormethylbenzyloxy)phenyl)-1-naphthyl)cumarin und trans-4-Hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluormethylbenzyloxy)phenyl)-1-naphthyl)cumarin |
| Estonian eesti | flokumafeen (ISO) reaktsioonimass: cis -4-hüdroksü-3-(1,2,3,4-tetrahüdro-3-(4-(4-trifluorometüülbensüüloksü)fenüül)-1-naftüül)kumariin ja trans -4-hüdroksü-3-(1,2,3,4-tetrahüdro-3-(4-(4-trifluorometüülbensüüloksü)fenüül)-1-naftüül)kumariin |
| Greek ελληνικά | φλοκουμαφένη (ISO) Μείγμα: cis -4-υδροξυ-3-(1,2,3,4-τετραϋδρο-3-(4-(4-τριφθορομεθυλοβενζυλοξυ)φαινυλο)-1-ναφθυλο)κουμαρίνης και trans -4-υδροξυ-3-(1,2,3,4-τετραϋδρο-3-(4-(4-τριφθορομεθυλοβενζυλοξυ)φαινυλο)-1-ναφθυλο)κουμαρίνης |
| English English | flocoumafen (ISO) reaction mass of: cis-4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluoromethylbenzyloxy)phenyl)-1-naphthyl)coumarin and trans-4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluoromethylbenzyloxy)phenyl)-1-naphthyl)coumarin |
| French français | flocoumafen (ISO) masse de réaction de cis -4-hydroxy-3-(1,2,3,4-tétrahydro-3-(4-(4-trifluorométhylbenzyloxy)phényl)-1-naphtyl)coumarine et de trans -4-hydroxy-3-(1,2,3,4-tétrahydro-3-(4-(4-trifluorométhylbenzyloxy)phényl)-1-naphtyl)coumarine |
| Croatian hrvatski | flokumafen (ISO) smjesa koja nastaje reakcijom: cis-4-hidroksi-3-(1,2,3,4-tetrahidro-3-(4-(4-trifluorometilbenziloksi)fenil)-1-naftil)kumarina i trans-4-hidroksi-3-(1,2,3,4-tetrahidro-3-(4-(4-trifluorometilbenziloksi)fenil)-1-naftil)kumarina |
| Italian italiano | flocoumafen (ISO) massa di reazione di: cis-4-idrossi-3-(1,2,3,4-tetraidro- 3-(4-(4-trifluorometilbenzilossi)fenil)-1-naftil)coumarina e trans-4-idrossi-3-(1,2,3,4-tetraidro-3-(4-(4-trifluorometilbenzilossi)fenil)-1-naftil)coumarina |
| Latvian latviešu | flokumafēns ( ISO ) cis -4-hidroksi-3-(1,2,3,4-tetrahidro-3-(4-(4-trifluormetilbenziloksi)fenil)-1-naftil)kumarīna un trans -4-hidroksi-3-(1,2,3,4-tetrahidro-3-(4-(4-trifluormetilbenziloksi)fenil)-1-naftil)kumarīna reakcijas masa |
| Lithuanian lietuvių | flokumafenas (ISO) cis-4-hidroksi-3-(1,2,3,4-tetrahidro-3-(4-(4-trifluormetilbenziloksi)fenil)-1-naftil)kumarino ir trans-4-hidroksi-3-(1,2,3,4-tetrahidro-3-(4-(4-trifluormetilbenziloksi)fenil)-1-naftil)kumarino reakcijos masė |
| Hungarian magyar | flokumafen (ISO) cisz-4-hidroxi-3-(1,2,3,4-tetrahidro-3-(4-(4-trifluormetilbenziloxi)fenil)-1-naftil)kumarin és transz-4-hidroxi-3-(1,2,3,4-tetrahidro-3-(4-(4-trifluormetilbenziloxi)fenil)-1-naftil)kumarin keveréke |
| Maltese Malti | flokumafen (ISO) massa ta' reazzjoni ta': cis-4-idrossi-3-(1,2,3,4-tetraidro-3-(4-(4-trifluworometilbenżilossi)fenil)-1-naftil)kumarin u trans-4-idrossi-3-(1,2,3,4-tetraidro-3-(4-(4-trifluworometilbenżilossi)fenil)-1-naftil)kumarin |
| Dutch Nederlands | flocumafen (ISO) reactiemassa van: cis -4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluormethylbenzyloxy)fenyl)-1-naftyl)cumarine en trans -4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluormethylbenzyloxy)fenyl)-1-naftyl)cumarine |
| Polish polski | flokumafen (ISO) mieszanina poreakcyjna cis-4-hydroksy-3-{3-[4-(4-trifluorometylobenzyloksy)fenylo]-1,2,3,4-tetrahydro-1-naftylo}kumaryny i trans-4-hydroksy-3-{3-[4-(4-trifluorometylobenzyloksy)fenylo]-1,2,3,4-tetrahydro-1-naftylo}kumaryny |
| Portuguese português | flocumafena (ISO) Mistura reacional de: cis -4-hidroxi-3-(1,2,3,4-tetra-hidro-3-(4-(4-trifluorometilbenziloxi)fenil)-1-naftil)cumarina e trans -4-hidroxi-3-(1,2,3,4-tetra-hidro-3-(4-(4-trifluorometilbenziloxi)fenil)-1-naftil)cumarina |
| Romanian română | flocumafen (ISO) masa de reacție a: cis-4-hidroxi-3-(1,2,3,4-tetrahidro-3-(4-(4-trifluorometilbenziloxi)fenil)-1-naftil)cumarină și trans-4-hidroxi-3-(1,2,3,4-tetrahidro-3-(4-(4-trifluoromethilbenziloxi)fenil)-1-naftil)cumarină |
| Slovak slovenčina | flokumafén (ISO) reakčná zmes zložená z týchto látok: cis-4-hydroxy-3-[3-(4-{[4-(trifluórmetyl)benzyl]oxy}fenyl)-1,2,3,4-tetrahydro-1-naftyl]-2H-chromén-2-ón a trans-4-hydroxy-3-[3-(4-{[4-(trifluórmetyl)benzyl]oxy}fenyl)-1,2,3,4-tetrahydro-1-naftyl]-2H-chromén-2-ón |
| Slovenian slovenščina | flokumafen (ISO) reakcijska zmes: cis-4-hidroksi-3-(1,2,3,4-tetrahidro-3-(4-(4-trifluorometilbenziloksi)fenil)-1-naftil)kumarina in trans-4-hidroksi-3-(1,2,3,4-tetrahidro-3-(4-(4-trifluorometilbenziloksi)fenil)-1-naftil)kumarina |
| Finnish suomi | flokumafeeni (ISO) seuraavien reaktiomassa: cis-4-hydroksi-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluorimetyylibentsyylioksi)fenyyli)-1-naftyyli)kumariini; trans-4-hydroksi-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluorimetyylibentsyylioksi)fenyyli)-1-naftyyli)kumariini |
| Swedish svenska | flokumafen (ISO) reaktionsmassa av cis-4-hydroxi-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluormetylbensyloxi)fenyl)-1-naftyl)kumarin och trans-4-hydroxi-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluormetylbensyloxi)fenyl)-1-naftyl)kumarin |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Flocoumafen GHS label elements
Everything CLP Annex VI fixes for Flocoumafen, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Flocoumafen
- May damage the unborn child.
- Fatal if inhaled.
- Fatal in contact with skin.
- Fatal if swallowed.
- Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF INHALED:
- Immediately call a POISON CENTER/doctor/…
- Get medical advice/attention if you feel unwell.
- Rinse mouth.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Flocoumafen in the GHS label constructor →
07 · Health hazards
Flocoumafen health hazards and exposure limits
Flocoumafen hazard summary
A vitamin K antagonist--causes clotting factor disruption and bleeding tendency; More embryotoxic than teratogenic in studies with rats and chickens; Non-lethal oral doses caused decrease in ovarian weight and transient infertility in female rats; [HSDB] Can be absorbed through skin; May cause problems with blood clotting, with symptoms appearing days after exposure; [ICSC] Second generation anticoagulant rodenticide; Rapidly absorbed by blood following single oral dose (maximum plasma concentration in four hours); Highest tissue accumulation in the liver (mostly unchanged parent compound); No pathological changes observed in rats fed non-lethal doses; Not irritating to skin or eyes of rabbits; Not sensitizing to guinea pig skin; No evidence of mutagenicity in any studies (i.e. reverse gene mutation, chromosomal aberrations); [INCHEM] See Warfarin.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
Flocoumafen properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Flocoumafen melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 186 °C (366.8 °F) | range, midpoint shown | HSDB |
| 167 °C (332.6 °F) | range, midpoint shown | ICSC |
Flocoumafen density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.4 g/cm³ | ICSC |
Flocoumafen solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | In acetone >600, ethanol 34, xylene 33, octanol 44 (all in g/l). | HSDB | |
| Solubility in acetone, alcohol, chloroform, dichloromethane: >10 g/l. | HSDB | ||
| In water, 1.10 mg/l, temp not specified | HSDB |
Flocoumafen vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 1e-12 mmHg | at 25 °C | HSDB |
| Vapor pressure at 20 °C: negligible | at 20 °C | ICSC |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Flocoumafen storage and handling
Flocoumafen safe storage
Separated from food and feedstuffs. Well closed. Store in an area without drain or sewer access.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Flocoumafen storage conditions
Store in original container.
Source: Hazardous Substances Data Bank (HSDB)
Planning storage for a mix of chemicals? Check Flocoumafen in the storage compatibility matrix →
10 · Questions
Flocoumafen — frequently asked questions
What is the CAS number of Flocoumafen?
The CAS number of Flocoumafen is 90035-08-8. Its EC number is 421-960-0.
What is the chemical formula of Flocoumafen?
The molecular formula of Flocoumafen is C33H25F3O4 and its molecular weight is 542.5 g/mol.
What does a Flocoumafen label have to show?
Under CLP Annex VI the label for Flocoumafen carries the pictograms Health hazard, Skull and crossbones and Environment and the signal word is Danger.
Is Flocoumafen flammable?
CLP Annex VI assigns Flocoumafen no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Flocoumafen a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Flocoumafen. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the melting point of Flocoumafen?
The melting point reported for Flocoumafen is 186 °C (366.8 °F), range, midpoint shown (HSDB).
How should Flocoumafen be stored?
Store in original container. (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Flocoumafen
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