Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Folpet

Folpet is crystals from benzene.

CAS 133-07-3 Warning

01 · Identification

What Folpet is

Folpet is crystals from benzene. It melts at 177 °C, is slightly soluble in water.

Under the GHS it carries the signal word Warning. It is classed as carcinogens.

02 · Identifiers

Folpet identifiers and molecular data

Folpet CAS number and EC number

CAS number133-07-3
EC number205-088-6
Index number (CLP Annex VI)613-045-00-1

Folpet molecular formula and molecular weight

Chemical class Carcinogens

Other names for Folpet

  • folpet (ISO)
  • N-(trichloromethylthio)phthalimide

03 · GHS classification

Folpet hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Folpet pictograms and signal word

Signal wordWarning

Folpet hazard class and category

GHS hazard classes Folpet falls into
Hazard class Category From code Pictogram
Acute toxicity - inhalation GHS chapter 3.1 Category 4 H332 GHS07
Serious eye damage/eye irritation GHS chapter 3.3 Category 2A H319 GHS07
Skin sensitisation GHS chapter 3.4 Category 1 or 1A or 1B H317 GHS07
Carcinogenicity GHS chapter 3.6 Category 2 H351 GHS08
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

Folpet hazard statements (H-codes)

Hazard statements assigned to Folpet
CodeHazard statement
H351 Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H332 Harmful if inhaled.
H319 Causes serious eye irritation.
H317 May cause an allergic skin reaction.
H400 Very toxic to aquatic life.

This page lists only the codes assigned to Folpet. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Folpet

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Folpet issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Folpet precautionary statements

CLP Annex VI assigns 18 precautionary statements to Folpet. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Folpet name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български фолпет (ISO) N -(трихлорометилтио)фталимид
Spanish español Folpet (ISO) N -(triclorometiltio)ftalimida
Czech čeština folpet (ISO) N -(trichlormethylsulfanyl)ftalimid
Danish dansk folpet (ISO) N -(trichlormethylthio)phthalimid
German Deutsch Folpet (ISO) N -(Trichlormethylthio)phthalimid
Estonian eesti folpeet (ISO) N -(triklorometüültio)ftaalimiid
Greek ελληνικά folpet (φολπέτ) (ISO) N -(τριχλωρομεθυλοθειο)φθαλιμίδιο
English English folpet (ISO) N -(trichloromethylthio)phthalimide
French français folpet (ISO) N -(trichlorométhylthio)phtalimide
Croatian hrvatski folpet (ISO) N -(triklormetiltio)ftalimid
Italian italiano folpet (ISO) N -(triclorometiltio)ftalimmide
Latvian latviešu folpets (ISO) N -(trihlormetiltio)ftalimīds
Lithuanian lietuvių folpetas (ISO) N -(trichlormetiltio)ftalimidas
Hungarian magyar folpet (ISO) N -(triklórmetiltio)ftálimid
Maltese Malti folpet (ISO) N -(triklorometiltijo)ftalimmid
Dutch Nederlands folpet (ISO) N -(trichloormethylthio)ftaalimide
Polish polski folpet (ISO) N -(trichlorometylotio)ftalimid
Portuguese português folpete (ISO) N -(triclorometiltio)ftalimida
Romanian română folpet (ISO) N -(triclorometiltio)ftalimidă
Slovak slovenčina folpet (ISO) N -(trichlórmetylsulfanyl)ftalimid
Slovenian slovenščina folpet (ISO) N -(triklorometiltio)ftalimid
Finnish suomi folpetti (ISO) N -(trikloorimetyylitio)ftaali-imidi
Swedish svenska folpet (ISO) N -(triklormetyltio)ftalimid

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Folpet GHS label elements

Everything CLP Annex VI fixes for Folpet, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS08 Health hazard pictogramGHS07 Exclamation mark pictogramGHS09 Environment pictogram

Warning

Folpet

  • Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Harmful if inhaled.
  • Causes serious eye irritation.
  • May cause an allergic skin reaction.
  • Very toxic to aquatic life.
  • Obtain special instructions before use.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Avoid breathing dust/fume/gas/mist/vapours/spray.
  • Wash thoroughly after handling.
  • Use only outdoors or in a well-ventilated area.
  • Contaminated work clothing should not be allowed out of the workplace.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF INHALED:
  • IF IN EYES:
  • IF exposed or concerned:
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Get medical advice/attention.
  • If skin irritation or rash occurs:
  • If eye irritation persists:
  • Remove contact lenses, if present and easy to do. Continue rinsing.
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Folpet in the GHS label constructor →

07 · Health hazards

Folpet health hazards and exposure limits

Folpet carcinogenicity classification

Cancer Classification: Group B2 Probable Human

Source: Hazardous Substances Data Bank (HSDB)

CLASSIFICATION: B2; probable human carcinogen. BASIS FOR CLASSIFICATION: Folpet has induced carcinoma and adenoma of the duodenum (an unusual site) in both sexes of CD-1 and B6C3F1 mice. Folpet is also mutagenic in several in vitro assays and is an structural analogue of captan, which has been shown to induce carcinoma in the duodenum of two mouse strains. HUMAN CARCINOGENICITY DATA: None. ANIMAL CARCINOGENICITY DATA: Sufficient.

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

08 · Physical and chemical properties

Folpet properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Folpet melting point

Property Value Conditions Source
Melting point 177 °C (350.6 °F) HSDB

Folpet density

Property Value Conditions Source
Density 1.72 g/cm³ at 20 °C HSDB

Folpet solubility

Property Value Conditions Source
Solubility Slightly soluble in organic solvents. HSDB
87 g/L chloroform; 22 g/L benzene; 12.5 g/L isopropanol HSDB
In carbon tetrachloride 6, toluene 26, methanol 3 (all in g/L at 25 °C) at 25 °C HSDB

Folpet vapor pressure

Property Value Conditions Source
Vapor pressure 157.513 mmHg at 25 °C HSDB
1.6e-7 mmHg Haz-Map
Vapor pressure, Pa at 20 °C: at 20 °C ICSC

Folpet corrosivity

Property Value Conditions Source
Corrosivity NON-CORROSIVE; DECOMP PRODUCTS ARE CORROSIVE HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

Folpet storage and handling

Folpet safe storage

Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access. Separated from food and feedstuffs.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Folpet storage conditions

Store in dry place at ambient or lower temperatures.

Source: Hazardous Substances Data Bank (HSDB)

Folpet incompatible materials

... Incompatible with strongly alkaline material.

Source: Hazardous Substances Data Bank (HSDB)

Folpet reactivity

A halogenated phthalimide.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Folpet in the storage compatibility matrix →

10 · Questions

Folpet — frequently asked questions

What is the CAS number of Folpet?

The CAS number of Folpet is 133-07-3. Its EC number is 205-088-6.

What does a Folpet label have to show?

Under CLP Annex VI the label for Folpet carries the pictograms Health hazard, Exclamation mark and Environment and the signal word is Warning.

Is Folpet flammable?

CLP Annex VI assigns Folpet no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is Folpet a carcinogen?

CLP Annex VI assigns Folpet H351 — suspected of causing cancer. That is category 2: the evidence points that way but is not conclusive.

What is the melting point of Folpet?

The melting point reported for Folpet is 177 °C (350.6 °F) (HSDB).

How should Folpet be stored?

Store in dry place at ambient or lower temperatures. (Hazardous Substances Data Bank (HSDB))

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