Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Hexachlorobenzene

Hexachlorobenzene is white needles.

CAS 118-74-1 C6Cl6 284.8 g/mol Danger

01 · Identification

What Hexachlorobenzene is

Hexachlorobenzene is white needles. Its molecular formula is C6Cl6 and its molecular weight is 284.8 g/mol. It boils at 325 °C, melts at 229 °C.

Under the GHS it carries the signal word Danger. It is classed as hazardous Air Pollutants (HAPs).

02 · Identifiers

Hexachlorobenzene identifiers and molecular data

Hexachlorobenzene CAS number and EC number

CAS number118-74-1
EC number204-273-9
Index number (CLP Annex VI)602-065-00-6

Hexachlorobenzene molecular formula and molecular weight

Molecular formulaC6Cl6
Molecular weight284.8 g/mol
Chemical class Hazardous Air Pollutants (HAPs)

03 · GHS classification

Hexachlorobenzene hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Hexachlorobenzene pictograms and signal word

Signal wordDanger

Hexachlorobenzene hazard class and category

GHS hazard classes Hexachlorobenzene falls into
Hazard class Category From code Pictogram
Carcinogenicity GHS chapter 3.6 Category 1A or 1B H350 GHS08
Specific target organ toxicity - repeated exposure GHS chapter 3.9 Category 1 H372 GHS08
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

Hexachlorobenzene hazard statements (H-codes)

Hazard statements assigned to Hexachlorobenzene
CodeHazard statement
H350 May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H372 Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Hexachlorobenzene. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Hexachlorobenzene

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Hexachlorobenzene issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Hexachlorobenzene precautionary statements

CLP Annex VI assigns 10 precautionary statements to Hexachlorobenzene. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Hexachlorobenzene name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български хексахлоробензен
Spanish español Hexaclorobenceno
Czech čeština hexachlorbenzen
Danish dansk hexachlorbenzen
German Deutsch Hexachlorbenzol
Estonian eesti heksaklorobenseen
Greek ελληνικά εξαχλωροβενζόλιο
English English hexachlorobenzene
French français hexachlorobenzène
Croatian hrvatski heksaklorbenzen
Italian italiano esaclorobenzene
Latvian latviešu heksahlorbenzols
Lithuanian lietuvių heksachlorbenzenas
Hungarian magyar hexaklórbenzol
Maltese Malti eżaklorobenżen
Dutch Nederlands hexachloorbenzeen
Polish polski heksachlorobenzen
Portuguese português hexaclorobenzeno
Romanian română hexaclorbenzen
Slovak slovenčina hexachlórbenzén
Slovenian slovenščina heksaklorobenzen
Finnish suomi heksaklooribentseeni
Swedish svenska hexaklorbensen

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Hexachlorobenzene GHS label elements

Everything CLP Annex VI fixes for Hexachlorobenzene, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS08 Health hazard pictogramGHS09 Environment pictogram

Danger

Hexachlorobenzene

  • May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Obtain special instructions before use.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF exposed or concerned:
  • Get medical advice/attention.
  • Get medical advice/attention if you feel unwell.
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Hexachlorobenzene in the GHS label constructor →

07 · Health hazards

Hexachlorobenzene health hazards and exposure limits

Hexachlorobenzene hazard summary

Hexachlorobenzene was widely used as a pesticide to protect the seeds of onions and sorghum, wheat, and other grains against fungus until 1965. It was also used to make fireworks, ammunition, and synthetic rubber. Currently, there are no commercial uses of hexachlorobenzene in the United States. Hexachlorobenzene is a white crystalline solid that is not very soluble in water. It does not occur naturally in the environment. It is formed as a by-product while making other chemicals, in the waste streams of chloralkali and wood-preserving plants, and when burning municipal waste.

Source: Agency for Toxic Substances and Disease Registry (ATSDR)

Hexachlorobenzene carcinogenicity classification

IARC classification Group 2B — Possibly carcinogenic to humans
IARC monographs Volume 79: (2001) Some Thyrotropic Agents

Evaluation: There is inadequate evidence in humans for the carcinogenicity of hexachlorobenzene. There is sufficient evidence in experimental animals for the carcinogenicity of hexachlorobenzene. Overall evaluation: Hexachlorobenzene is possibly carcinogenic to humans (Group 2B).

Source: Hazardous Substances Data Bank (HSDB)

CLASSIFICATION: B2; probable human carcinogen. BASIS FOR CLASSIFICATION: Hexachlorobenzene, when administered orally, has been shown to induce tumors in the liver, thyroid, and kidney in three rodent species. HUMAN CARCINOGENICITY DATA: Inadequate. ANIMAL CARCINOGENICITY DATA: Sufficient.

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

08 · Physical and chemical properties

Hexachlorobenzene properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Hexachlorobenzene boiling point

Property Value Conditions Source
Boiling point 325 °C (617 °F) HSDB
322.22 °C (612 °F) OSHA
325 °C (617 °F) at 760 mmHg DOE PAC

Hexachlorobenzene melting point

Property Value Conditions Source
Melting point 228.83 °C (443.9 °F) HSDB
200 °C (392 °F) Technical product HSDB
231 °C (447.8 °F) ICSC

Hexachlorobenzene density

Property Value Conditions Source
Density 2 g/cm³ ICSC
2.044 g/cm³ at 23 °C HSDB
2.044 g/cm³ at 24 °C CAMEO

Hexachlorobenzene solubility

Property Value Conditions Source
Solubility Sparingly soluble in cold alcohol; soluble in benzene, chloroform, and ether HSDB
Soluble in carbon disulfide; sparingly soluble in carbon tetrachloride HSDB
In water, 4.7X10-3 mg/L at 25 °C at 25 °C HSDB

Hexachlorobenzene vapor pressure

Property Value Conditions Source
Vapor pressure 0.000007501 mmHg at 20 °C ICSC
0.0000172 mmHg at 25 °C HSDB
1 mmHg at 114.39 °C CAMEO

Hexachlorobenzene flash point

Property Value Conditions Source
Flash point 242 °C (467.6 °F) closed cup HSDB
242.22 °C (468 °F) CAMEO
242 °C (467.6 °F) ICSC

Hexachlorobenzene vapor density

Property Value Conditions Source
Vapor density 9.83 (air = 1) HSDB
9.8 (air = 1) CAMEO

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Hexachlorobenzene fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Hexachlorobenzene fire potential

Not flammable or combustible.

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

Hexachlorobenzene storage and handling

Hexachlorobenzene safe storage

Separated from food and feedstuffs. Well closed. Store only in original container. Store in an area without drain or sewer access.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Hexachlorobenzene storage conditions

Separated from food and feedstuffs. Well closed.

Source: Hazardous Substances Data Bank (HSDB)

Hexachlorobenzene incompatible materials

DIMETHYL FORMAMIDE AND HEXACHLOROBENZENE REACT VIOLENTLY ABOVE 65 °C.

Source: Hazardous Substances Data Bank (HSDB)

Hexachlorobenzene reactivity

HEXACHLOROBENZENE reacts violently with dimethylformamide. (NTP, 1992).

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Hexachlorobenzene in the storage compatibility matrix →

11 · Transport

Hexachlorobenzene UN number and transport classification

Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.

Hexachlorobenzene under UN 2729 — shipping name, class and packing group

Europe · ADR 2025, Table A

Proper shipping name (3.1.2) Class Classification code PG Labels (column 5)
HEXACHLOROBENZENE 6.1 T2 III
  • ADR label model 6.1 — Toxic substance
6.1

Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 6.1 is “Toxic substances” (ADR 2.1.1.1).

Proper shipping name (column 2) Class or division PG Labels (column 6)
Hexachlorobenzene 6.1 III
  • US DOT POISON label (§172.430)
6.1

Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 6.1 is “Poisonous materials” (49 CFR 173.2).

Full UN 2729 entry — special provisions, packing instructions, quantity limits and the orange plate →

12 · Questions

Hexachlorobenzene — frequently asked questions

What is the CAS number of Hexachlorobenzene?

The CAS number of Hexachlorobenzene is 118-74-1. Its EC number is 204-273-9.

What is the chemical formula of Hexachlorobenzene?

The molecular formula of Hexachlorobenzene is C6Cl6 and its molecular weight is 284.8 g/mol.

What does a Hexachlorobenzene label have to show?

Under CLP Annex VI the label for Hexachlorobenzene carries the pictograms Health hazard and Environment and the signal word is Danger.

Is Hexachlorobenzene flammable?

CLP Annex VI assigns Hexachlorobenzene no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 242 °C (467.6 °F), closed cup (HSDB).

Is Hexachlorobenzene a carcinogen?

Yes. CLP Annex VI classifies Hexachlorobenzene as a category 1A or 1B carcinogen and assigns it H350: may cause cancer. IARC places it in Group 2B: possibly carcinogenic to humans.

What is the boiling point of Hexachlorobenzene?

The boiling point reported for Hexachlorobenzene is 325 °C (617 °F) (HSDB).

What is the melting point of Hexachlorobenzene?

The melting point reported for Hexachlorobenzene is 228.83 °C (443.9 °F) (HSDB).

How should Hexachlorobenzene be stored?

Separated from food and feedstuffs. Well closed. (Hazardous Substances Data Bank (HSDB))

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