Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Imazalil

Imazalil is a slightly yellow to brown crystalline mass.

CAS 35554-44-0 C14H14Cl2N2O 297.2 g/mol Danger

01 · Identification

What Imazalil is

Imazalil is a slightly yellow to brown crystalline mass. Its molecular formula is C14H14Cl2N2O and its molecular weight is 297.2 g/mol. It boils at 347 °C, melts at 52.7 °C.

Under the GHS it carries the signal word Danger.

02 · Identifiers

Imazalil identifiers and molecular data

Imazalil CAS number and EC number

CAS number35554-44-0
EC number252-615-0
Index number (CLP Annex VI)613-042-00-5

Imazalil molecular formula and molecular weight

Molecular formulaC14H14Cl2N2O
Molecular weight297.2 g/mol

Other names for Imazalil

  • imazalil (ISO)
  • 1-[2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole

03 · GHS classification

Imazalil hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Imazalil pictograms and signal word

Signal wordDanger

Imazalil hazard class and category

GHS hazard classes Imazalil falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 3 H301 GHS06
Acute toxicity - inhalation GHS chapter 3.1 Category 4 H332 GHS07
Serious eye damage/eye irritation GHS chapter 3.3 Category 1 H318 GHS05
Carcinogenicity GHS chapter 3.6 Category 2 H351 GHS08
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Imazalil hazard statements (H-codes)

Hazard statements assigned to Imazalil
CodeHazard statement
H351 Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H301 Toxic if swallowed.
H332 Harmful if inhaled.
H318 Causes serious eye damage.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Imazalil. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Imazalil

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Imazalil issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Imazalil precautionary statements

CLP Annex VI assigns 17 precautionary statements to Imazalil. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Imazalil name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български имазалил (ISO) 1-[2-(алилокси)-2-(2,4-дихлорофенил)етил]-1 H -имидазол
Spanish español imazalilo (ISO) 1-[2-(aliloxi)-2-(2,4-diclorofenil)etil]-1 H -imidazol
Czech čeština imazalil (ISO) 1-[2-allyloxy-2-(2,4-dichlorfenyl)ethyl]-1 H -imidazol
Danish dansk imazalil (ISO) 1-[2-(allyloxy)-2-(2,4-dichlorphenyl)ethyl]-1H-imidazol
German Deutsch Imazalil (ISO) 1-[2-(Allyloxy)-2-(2,4-dichlorphenyl)ethyl]-1 H -imidazol
Estonian eesti imasaliil (ISO) 1-[2-(allüüloksü)-2-(2,4-diklorofenüül)etüül]-1 H -imidasool
Greek ελληνικά imazalil/ιμαζαλίλη (ISO) 1-[2-(αλλυλοξυ)-2-(2,4-διχλωροφαινυλ)αιθυλο]-1 Η -ιμιδαζόλιο
English English imazalil (ISO) 1-[2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl]-1 H -imidazole
French français imazalil (ISO) 1-[2-(allyloxy)-2-(2,4-dichlorophényl)éthyl]-1 H -imidazole
Croatian hrvatski imazalil (ISO) 1-[2-(aliloksi)-2-(2,4-diklorofenil)etil]-1 H -imidazol
Italian italiano imazalil (ISO) 1-[2-(allilossi)-2-(2,4-diclorofenil)etil]-1H-imidazolo
Latvian latviešu imazalils ( ISO ) 1-[2-(aliloksi)-2-(2,4-dihlorfenil)etil]-1 H -imidazols
Lithuanian lietuvių imazalilas (ISO) 1-[2-(aliloksi)-2-(2,4-dichlorfenil)etil]-1H-imidazolas
Hungarian magyar imazalil (ISO) 1-[2-(alliloxi)-2-(2,4-diklórfenil)etil]-1-H-imidazol
Maltese Malti imażalil (ISO) 1-[2-(alliloxi)-2-(2,4-diklorofenil)etil]-1 H -imidażol
Dutch Nederlands imazalil (ISO) 1-[2-(allyloxy)-2-(2,4-dichloorfenyl)ethyl]-1 H -imidazool
Polish polski imazalil (ISO) 1-[2-alliloksy-2-(2,4-dichlorofenylo)etylo]-1 H -imidazol
Portuguese português imazalil (ISO) 1-[2-(aliloxi)-2-(2,4-diclorofenil)etil]-1 H -imidazole
Romanian română imazalil (ISO) 1-[2-(aliloxi)-2-(2,4-diclorofenil)etil]-1 H -imidazol
Slovak slovenčina imazalil (ISO) 1-[2-(alyloxy)-2-(2,4-dichlórfenyl)etyl]-1H-imidazol
Slovenian slovenščina imazalil (ISO) 1-[2-(aliloksi)-2-(2,4-diklorofenil)etil]-1 H -imidazol
Finnish suomi 1-[2-(Allyylioksi)-2-(2,4-dikloorifenyyli)etyyli]-1 H -imidatsoli Imatsaliili (ISO)
Swedish svenska imazalil (ISO) 1-[2-(allyloxi)-2-(2,4-diklorfenyl)etyl]-1 H -imidazol

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Imazalil GHS label elements

Everything CLP Annex VI fixes for Imazalil, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS08 Health hazard pictogramGHS06 Skull and crossbones pictogramGHS05 Corrosion pictogramGHS09 Environment pictogram

Danger

Imazalil

  • Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Toxic if swallowed.
  • Harmful if inhaled.
  • Causes serious eye damage.
  • Very toxic to aquatic life with long lasting effects.
  • Obtain special instructions before use.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Use only outdoors or in a well-ventilated area.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF INHALED:
  • IF IN EYES:
  • IF exposed or concerned:
  • Immediately call a POISON CENTER/doctor/
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Get medical advice/attention.
  • Rinse mouth.
  • Remove contact lenses, if present and easy to do. Continue rinsing.
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Imazalil in the GHS label constructor →

07 · Health hazards

Imazalil health hazards and exposure limits

Imazalil hazard summary

An eye irritant; May cause liver injury; [ICSC] Likely to be carcinogenic to humans; Causes liver adenomas in mice; [EPA REDs] A skin and severe eye irritant; Although the Buehler assay was negative on a 13.5% formulation, cases of sensitivity to the compound have been previously described in Europe and in Central America. The technical material is labeled as a potential sensitizer. [HSDB] Skin designation; [MAK] An irritant; May cause serious eye injury; Can be absorbed through skin; [MSDSonline]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Imazalil carcinogenicity classification

Cancer Classification: Likely to be Carcinogenic to Humans

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

08 · Physical and chemical properties

Imazalil properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Imazalil boiling point

Property Value Conditions Source
Boiling point 347 °C (656.6 °F) HSDB
333 °C (631.4 °F) range, midpoint shown ICSC
347 °C (656.6 °F) at 760 mmHg HMDB

Imazalil melting point

Property Value Conditions Source
Melting point 52.7 °C (126.9 °F) HSDB
50 °C (122 °F) ICSC

Imazalil density

Property Value Conditions Source
Density 1.2 g/cm³ ICSC
1.348 g/cm³ at 26 °C HSDB

Imazalil solubility

Property Value Conditions Source
Solubility In water, 0.18 g/L at pH 7.6, 20 °C at 20 °C HSDB
Solubility in water, g/100ml at 20 °C: 0.14 at 20 °C ICSC

Imazalil vapor pressure

Property Value Conditions Source
Vapor pressure 0.0000012 mmHg at 20 °C HSDB
0.00000119 mmHg Haz-Map
Vapor pressure at 20 °C: negligible at 20 °C ICSC

Imazalil flash point

Property Value Conditions Source
Flash point 192 °C (377.6 °F) HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Imazalil fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Imazalil fire potential

Combustible. Liquid formulations containing organic solvents may be flammable.

Source: Hazardous Substances Data Bank (HSDB)

Solubility

In acetone, dichloromethane, ethanol, methanol, isopropanol, xylene, toluene, benzene > 500g/L at 20 °C. In hexane 19 g/L at 20 °C. Also soluble in heptane and petroleum ether.

Source: HSDB

10 · Handling and storage

Imazalil storage and handling

Imazalil safe storage

Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed. Keep in a well-ventilated room.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Imazalil storage conditions

Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed. Keep in a well-ventilated room.

Source: Hazardous Substances Data Bank (HSDB)

Imazalil incompatible materials

Incompatible with alkaline materials.

Source: Hazardous Substances Data Bank (HSDB)

Imazalil reactivity

IMAZALIL is an imidazole derivative.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Imazalil in the storage compatibility matrix →

11 · Questions

Imazalil — frequently asked questions

What is the CAS number of Imazalil?

The CAS number of Imazalil is 35554-44-0. Its EC number is 252-615-0.

What is the chemical formula of Imazalil?

The molecular formula of Imazalil is C14H14Cl2N2O and its molecular weight is 297.2 g/mol.

What does a Imazalil label have to show?

Under CLP Annex VI the label for Imazalil carries the pictograms Health hazard, Skull and crossbones, Corrosion and Environment and the signal word is Danger.

Is Imazalil flammable?

CLP Annex VI assigns Imazalil no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 192 °C (377.6 °F) (HSDB).

Is Imazalil a carcinogen?

CLP Annex VI assigns Imazalil H351 — suspected of causing cancer. That is category 2: the evidence points that way but is not conclusive.

What is the boiling point of Imazalil?

The boiling point reported for Imazalil is 347 °C (656.6 °F) (HSDB).

What is the melting point of Imazalil?

The melting point reported for Imazalil is 52.7 °C (126.9 °F) (HSDB).

How should Imazalil be stored?

Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed. Keep in a well-ventilated room. (Hazardous Substances Data Bank (HSDB))

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