Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Isoxathion

Isoxathion is a yellowish liquid with an ester-like odor.

CAS 18854-01-8 C13H16NO4PS 313.31 g/mol Danger

01 · Identification

What Isoxathion is

Isoxathion is a yellowish liquid with an ester-like odor. Its molecular formula is C13H16NO4PS and its molecular weight is 313.31 g/mol.

Under the GHS it carries the signal word Danger.

02 · Identifiers

Isoxathion identifiers and molecular data

Isoxathion CAS number and EC number

CAS number18854-01-8
EC number242-624-8
Index number (CLP Annex VI)015-131-00-9

Isoxathion molecular formula and molecular weight

Molecular formulaC13H16NO4PS
Molecular weight313.31 g/mol

Other names for Isoxathion

  • isoxathion (ISO)
  • O,O-diethyl O-5-phenylisoxazol-3-ylphosphorothioate

03 · GHS classification

Isoxathion hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Isoxathion pictograms and signal word

Signal wordDanger

Isoxathion hazard class and category

GHS hazard classes Isoxathion falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 3 H301 GHS06
Acute toxicity - dermal GHS chapter 3.1 Category 3 H311 GHS06
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Isoxathion hazard statements (H-codes)

Hazard statements assigned to Isoxathion
CodeHazard statement
H311 Toxic in contact with skin.
H301 Toxic if swallowed.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Isoxathion. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Isoxathion

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Isoxathion issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Isoxathion precautionary statements

CLP Annex VI assigns 10 precautionary statements to Isoxathion. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Isoxathion name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български изоксатион (ISO) O , O -диетилов О -5-фенилизоксазол-3-илов фосфоротиоат
Spanish español Isoxatión (ISO) fosforotioato de O , O -dietilo y O -5-fenilisoxazol-3-ilo
Czech čeština isoxathion (ISO) O, O -diethyl- O -(5-fenylisoxazol-3-yl)-fosforothioát
Danish dansk isoxathion (ISO) O, O- diethyl- O- 5-phenylisoxazol-3-ylthiophosphat
German Deutsch Isoxathion (ISO) O, O -Diethyl- O -5-phenylisoxazol-3-ylphosphorothioat
Estonian eesti isoksatioon (ISO) O , O -dietüül- O -5-fenüülisoksasool-3-üülfosforotioaat
Greek ελληνικά isoxathion (ισοξαθείο) (ISO) θειοφωσφορικό O , O -διαιθύλιο O -5-φαινυλισοξαζολ-3-ύλιο
English English isoxathion (ISO) O , O -diethyl O -5-phenylisoxazol-3-ylphosphorothioate
French français isoxathion (ISO) O -5-phénylisoxazol-3-ylphosphorothioate de O , O -diéthyle
Croatian hrvatski izoksation (ISO) O , O -dietil- O -5-fenil-izooksazol-3-il-fosforotioat
Italian italiano isoxathion (ISO) tiofosfato di O , O -dietile e O -5-fenilisossazol-3-ile
Latvian latviešu izoksations (ISO) O , O -dietil- O -5-fenilizoksazol-3-ilfosfortioāts
Lithuanian lietuvių izoksationas (ISO) O , O -dietil- O -5-fenilizoksazol-3-iltiofosfatas
Hungarian magyar izoxation (ISO) O , O -dietil- O -5-fenil-izoxazol-3-il-tiofoszfát
Maltese Malti isossatijon (ISO) O-5-fenilisossażol-3-ilfosforotijoat ta’ O , O -dietil
Dutch Nederlands isoxathion (ISO) O , O -diëthyl- O -5-fenylisoxazool-3-ylthiofosfaat
Polish polski izoksation (ISO) tiofosforan O, O-dietylu-O-5-fenyloizoksazol-3-ilu
Portuguese português isoxatião (ISO) tiofosfato de O , O -dietilo e de O -5-fenilisoxazol-3-ilo
Romanian română izoxation (ISO) tiofosfat de O, O -dietil și de O -5-fenilizoxazol-3-il
Slovak slovenčina izoxatión (ISO) O, O -dietyl- O -(5-fenylizoxazol-3-yl)-fosforotioát
Slovenian slovenščina izoksation (ISO) O , O -dietil O -5-fenilizoksazol-3-ilfosforotioat
Finnish suomi isoksationi (ISO) O , O -dietyyli- O -5-fenyyli-isoksatsol-3-yylifosforotioaatti
Swedish svenska isoxation (ISO) O , O -dietyl- O -5-fenylisoxazol-3-ylfosfortioat

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Isoxathion GHS label elements

Everything CLP Annex VI fixes for Isoxathion, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS06 Skull and crossbones pictogramGHS09 Environment pictogram

Danger

Isoxathion

  • Toxic in contact with skin.
  • Toxic if swallowed.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Do not eat, drink or smoke when using this product.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • Immediately call a POISON CENTER/doctor/
  • Rinse mouth.
  • Wash with plenty of water/
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Isoxathion in the GHS label constructor →

07 · Health hazards

Isoxathion health hazards and exposure limits

Isoxathion hazard summary

The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Physical and chemical properties

Isoxathion properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Isoxathion boiling point

Property Value Conditions Source
Boiling point 160 °C (320 °F) at 0.15 mmHg (reduced pressure) HSDB

Isoxathion solubility

Property Value Conditions Source
Solubility Readily soluble in organic solvents. HSDB
In water, 1.9 mg/l @ 25 °C at 25 °C HSDB

Isoxathion vapor pressure

Property Value Conditions Source
Vapor pressure 0.00000222 mmHg Haz-Map

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Questions

Isoxathion — frequently asked questions

What is the CAS number of Isoxathion?

The CAS number of Isoxathion is 18854-01-8. Its EC number is 242-624-8.

What is the chemical formula of Isoxathion?

The molecular formula of Isoxathion is C13H16NO4PS and its molecular weight is 313.31 g/mol.

What does a Isoxathion label have to show?

Under CLP Annex VI the label for Isoxathion carries the pictograms Skull and crossbones and Environment and the signal word is Danger.

Is Isoxathion flammable?

CLP Annex VI assigns Isoxathion no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is Isoxathion a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Isoxathion. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of Isoxathion?

The boiling point reported for Isoxathion is 160 °C (320 °F), at 0.15 mmHg (reduced pressure) (HSDB).

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