Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Maneb

Maneb is yellow powder; crystals from alcohol and is odorless.

CAS 12427-38-2 C4H6MnN2S4 265.3 g/mol Warning

01 · Identification

What Maneb is

Maneb is yellow powder; crystals from alcohol and is odorless. Its molecular formula is C4H6MnN2S4 and its molecular weight is 265.3 g/mol. It melts at 200 °C, is soluble in water.

Under the GHS it carries the signal word Warning. It is classed as flammable agents - 3rd degree.

02 · Identifiers

Maneb identifiers and molecular data

Maneb CAS number and EC number

CAS number12427-38-2
EC number235-654-8
Index number (CLP Annex VI)006-077-00-7

Maneb molecular formula and molecular weight

Molecular formulaC4H6MnN2S4
Molecular weight265.3 g/mol
Chemical class Flammable agents - 3rd degree

Other names for Maneb

  • maneb (ISO)
  • manganese ethylenebis(dithiocarbamate) (polymeric)

03 · GHS classification

Maneb hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Maneb pictograms and signal word

Signal wordWarning

Maneb hazard class and category

GHS hazard classes Maneb falls into
Hazard class Category From code Pictogram
Acute toxicity - inhalation GHS chapter 3.1 Category 4 H332 GHS07
Serious eye damage/eye irritation GHS chapter 3.3 Category 2A H319 GHS07
Skin sensitisation GHS chapter 3.4 Category 1 or 1A or 1B H317 GHS07
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

Maneb hazard statements (H-codes)

Hazard statements assigned to Maneb
CodeHazard statement
H361d Suspected of damaging the unborn child.
H332 Harmful if inhaled.
H319 Causes serious eye irritation.
H317 May cause an allergic skin reaction.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Maneb. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Maneb

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Maneb issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Maneb precautionary statements

CLP Annex VI assigns 16 precautionary statements to Maneb. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Maneb name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български манеб (ISO) манганов етиленбис(дитиокарбамат) (полимерен)
Spanish español Maneb (ISO) etilen-bis(ditiocarbamato) (polimérico) de manganeso
Czech čeština maneb (ISO) N, N' -ethylenbis(dithiokarbamát) manganatý (polymerní)
Danish dansk maneb (ISO) manganethylenbis(dithiocarbamat) (polymer)
German Deutsch Maneb (ISO) Manganethylenbis(dithiocarbamat) (Polymer)
Estonian eesti maneeb (ISO) mangaanetüleenbis(ditiokarbamaat) (polümeerne)
Greek ελληνικά maneb (μανέμπ) (ISO) μαγγάνιο, αιθυλενοδις(διθειοκαρβαμιδικό) (πολυμερές)
English English maneb (ISO) manganese ethylenebis(dithiocarbamate) (polymeric)
French français manèbe (ISO) éthylènebis(dithiocarbamate) de manganèse (polymère)
Croatian hrvatski maneb (ISO) manganov etilenbis(ditiokarbamat) (polimerni)
Italian italiano maneb (ISO) etilenebis(ditiocarbammato) (polimerico) di manganese
Latvian latviešu manebs (ISO) mangānetilēnbis(ditiokarbamāts) (polimērs)
Lithuanian lietuvių manebas (ISO) mangano etilenbis(ditiokarbamatas) (polimeras)
Hungarian magyar maneb (ISO) mangán etilén-bisz(ditiokarbamát) (polimer)
Maltese Malti maneb (ISO) manganiż etilenebis(ditijokarbamat) (polimeriku)
Dutch Nederlands maneb (ISO) mangaanethyleenbis(dithiocarbamaat) (polymeer)
Polish polski maneb (ISO) polimeryczny etylenobis (ditiokarbaminian) manganu
Portuguese português manebe (ISO) etilenobis(ditiocarbamato) de manganês polimérico
Romanian română maneb (ISO) mangan etilenbis(ditiocarbamat) (polimer)
Slovak slovenčina maneb (ISO) polymérny mangánium-etylénbis (ditiokarbamátu)
Slovenian slovenščina maneb (ISO) manganov etilenbis(ditiokarbamat) (polimerni)
Finnish suomi manebi (ISO) mangaanietyleenibis(ditiokarbamaatti) (polymeerinen)
Swedish svenska maneb (ISO) mangan etylenbis(ditiokarbamat) (polymer)

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Maneb GHS label elements

Everything CLP Annex VI fixes for Maneb, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS08 Health hazard pictogramGHS07 Exclamation mark pictogramGHS09 Environment pictogram

Warning

Maneb

  • Suspected of damaging the unborn child.
  • Harmful if inhaled.
  • Causes serious eye irritation.
  • May cause an allergic skin reaction.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Avoid breathing dust/fume/gas/mist/vapours/spray.
  • Wash thoroughly after handling.
  • Use only outdoors or in a well-ventilated area.
  • Contaminated work clothing should not be allowed out of the workplace.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF INHALED:
  • IF IN EYES:
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Get medical advice/attention.
  • If skin irritation or rash occurs:
  • If eye irritation persists:
  • Remove contact lenses, if present and easy to do. Continue rinsing.
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Maneb in the GHS label constructor →

07 · Health hazards

Maneb health hazards and exposure limits

Maneb carcinogenicity classification

IARC classification Group 3 — Not classifiable as to its carcinogenicity to humans
IARC monographs Volume 12: (1976) Some Carbamates, Thiocarbamates and Carbazides

No data are available in humans. Inadequate evidence of carcinogenicity in animals. OVERALL EVALUATION: Group 3: The agent is not classifiable as to its carcinogenicity to humans.

Source: Hazardous Substances Data Bank (HSDB)

Historically, it has been assumed that maneb's potential for carcinogenicity (as well as that of the other EBDCs, metiram and mancozeb) is due to the formation of the metabolite ETU, which is classified as a probable human carcinogen (B2) ... . On this basis, maneb cancer risk has been calculated by estimating exposure to maneb-derived ETU (including the metabolic conversion) and using the ETU cancer potency factor to provide a quantitative estimate of risk. In a 1999 Review, the /USSEPA/ concluded that cancer risk for maneb and the other EBDCs should continue to be evaluated in this way.

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

Maneb occupational exposure limits

US occupational exposure limits reported for Maneb. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
IDLH 500 mg/cu m /Manganese cmpds and fume, as Mn/ Hazardous Substances Data Bank (HSDB)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

Maneb properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Maneb melting point

Property Value Conditions Source
Melting point 200 °C (392 °F) OSHA
200 °C (392 °F) decomposes, decomposes HSDB

Maneb density

Property Value Conditions Source
Density 1.92 g/cm³ ICSC
1.92 g/cm³ at 25 °C HSDB

Maneb solubility

Property Value Conditions Source
Solubility Soluble in chloroform, pyridine HSDB

Maneb vapor pressure

Property Value Conditions Source
Vapor pressure 7.5e-8 mmHg OSHA
7.5e-8 mmHg at 25 °C HSDB
8e-8 mmHg Haz-Map

Maneb vapor density

Property Value Conditions Source
Vapor density 1.92 (air = 1) OSHA

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Maneb fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Maneb fire potential

May ignite spontaneously in air.

Source: Hazardous Substances Data Bank (HSDB)

Solubility

Practically insoluble in common organic solvents. Soluble in chelating agents (e.g. sodium salts of ethylenediaminetetraacetic acid) with the formation of complexes.

Source: HSDB

10 · Handling and storage

Maneb storage and handling

Maneb safe storage

Separated from acids and food and feedstuffs. Dry. Well closed. Keep in a well-ventilated room. Store only if stabilized.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Maneb storage conditions

This product must be stored in its sealed original containers, in well-aired places. It is recommended that the product's temperature should not exceed 25-30 °C. The containers must be stacked in such a way as to permit a free circulation of air also at the bottom & inside of the piles.

Source: Hazardous Substances Data Bank (HSDB)

Maneb incompatible materials

Water, acid, oxidizing materials. Heat or contact with moisture or acids causes rapid decomposition and the generation of toxic and flammable hydrogen sulfide and carbon disulfide.

Source: Hazardous Substances Data Bank (HSDB)

Maneb reactivity

The BPS Pesticide incident in Helena resulted in an explosion and death of three firemen. The burning of a 1,000 pound sack of Azinphos Methyl or the flashing of Maneb which was present on the facility may have caused the explosion.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Maneb in the storage compatibility matrix →

11 · Transport

Maneb UN number and transport classification

Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.

The same CAS number is shipped under more than one UN number. Which entry applies follows from the form and the concentration of the consignment — read the proper shipping name, not the CAS.

Maneb under UN 2210 — shipping name, class and packing group

Europe · ADR 2025, Table A

Proper shipping name (3.1.2) Class Classification code PG Labels (column 5)
MANEB or MANEB PREPARATION with not less than 60 % maneb 4.2 SW1 III
  • ADR label model 4.2 — Substance liable to spontaneous combustion
  • ADR label model 4.3 — Substance which emits flammable gas on contact with water
4.2, 4.3

Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 4.2 is “Substances liable to spontaneous combustion” (ADR 2.1.1.1).

Proper shipping name (column 2) Class or division PG Labels (column 6)
Maneb or Maneb preparations with not less than 60 percent maneb 4.2 III
  • US DOT SPONTANEOUSLY COMBUSTIBLE label (§172.422)
  • US DOT DANGEROUS WHEN WET label (§172.423)
4.2, 4.3

Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 4.2 is “Spontaneously combustible material” (49 CFR 173.2).

Full UN 2210 entry — special provisions, packing instructions, quantity limits and the orange plate →

Maneb under UN 2968 — shipping name, class and packing group

Europe · ADR 2025, Table A

Proper shipping name (3.1.2) Class Classification code PG Labels (column 5)
MANEB, STABILIZED or MANEB PREPARATION, STABILIZED against self-heating 4.3 W2 III
  • ADR label model 4.3 — Substance which emits flammable gas on contact with water
4.3

Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 4.3 is “Substances which, in contact with water, emit flammable gases” (ADR 2.1.1.1).

Proper shipping name (column 2) Class or division PG Labels (column 6)
Maneb stabilized or Maneb preparations, stabilized against self-heating 4.3 III
  • US DOT DANGEROUS WHEN WET label (§172.423)
4.3

Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 4.3 is “Dangerous when wet material” (49 CFR 173.2).

Full UN 2968 entry — special provisions, packing instructions, quantity limits and the orange plate →

12 · Questions

Maneb — frequently asked questions

What is the CAS number of Maneb?

The CAS number of Maneb is 12427-38-2. Its EC number is 235-654-8.

What is the chemical formula of Maneb?

The molecular formula of Maneb is C4H6MnN2S4 and its molecular weight is 265.3 g/mol.

What does a Maneb label have to show?

Under CLP Annex VI the label for Maneb carries the pictograms Health hazard, Exclamation mark and Environment and the signal word is Warning.

Is Maneb flammable?

CLP Annex VI assigns Maneb no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is Maneb a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Maneb. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health. IARC places it in Group 3: not classifiable as to its carcinogenicity to humans.

What is the melting point of Maneb?

The melting point reported for Maneb is 200 °C (392 °F) (OSHA).

How should Maneb be stored?

This product must be stored in its sealed original containers, in well-aired places. It is recommended that the product's temperature should not exceed 25-30 °C. The containers must be stacked in such a way as to permit a free circulation of air also at the bottom & inside of the piles. (Hazardous Substances Data Bank (HSDB))

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