Substance profile
Musk ketone
Musk ketone is yellow crystals with a sweet, very persistent, slightly animal musk odor.
01 · Identification
What Musk ketone is
Musk ketone is yellow crystals with a sweet, very persistent, slightly animal musk odor. Its molecular formula is C14H18N2O5 and its molecular weight is 294.3 g/mol. It melts at 136 °C.
Under the GHS it carries the signal word Warning.
02 · Identifiers
Musk ketone identifiers and molecular data
Musk ketone CAS number and EC number
Musk ketone molecular formula and molecular weight
Other names for Musk ketone
- 3,5-dinitro-2,6-dimethyl-4-tert-butylacetophenone
- 4'-tert-butyl-2',6'-dimethyl-3',5'-dinitroacetophenone
03 · GHS classification
Musk ketone hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Musk ketone pictograms and signal word
Musk ketone hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Carcinogenicity GHS chapter 3.6 | Category 2 | H351 | GHS08 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Musk ketone hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H351 | Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Musk ketone. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Musk ketone
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Musk ketone issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Musk ketone precautionary statements
CLP Annex VI assigns 7 precautionary statements to Musk ketone. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Musk ketone name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | мускус-кетон: 3,5-динитро-2,6-диметил-4- трет -бутилацетофенон 4′- трет -бутил-2′,6′-диметил-3′, 5′-динитроацетофенон |
| Spanish español | Cetona de almizcle 3,5-dinitro-2,6-dimetil-4- terc -butilacetofenona4'- terc -butil-2',6'-dimetil-3',5'-dinitroacetofenona |
| Czech čeština | mošusový keton 3,5-dinitro-2,6-dimethyl-4- terc -butylacetofenon1-(4- terc -butyl-2,6-dimethyl-3,5-dinitrofenyl)ethan-l-on |
| Danish dansk | moskusketon 3,5-dinitro-2,6-dimethyl-4- tert -butylacetophenon4'- tert -butyl-2',6'-dimethyl-3', 5'-dinitroacetophenon |
| German Deutsch | Moschus-Keton 3,5-Dinitro-2,6-dimethyl-4- tert - butylacetophenon4'- tert -Butyl-2', 6'-dimethyl-3', 5'-dinitroacetophenon |
| Estonian eesti | muskusketoon 3,5-dinitro-2,6-dimetüül-4- tert -butüülatsetofenoon4'- tert -butüül-2',6'-dimetüül-3',5'-dinitroatsetofenoon |
| Greek ελληνικά | μοσχοκετόνη 3,5-δινιτρο-2,6-διμεθυλο-4- tert -βουτυλακετοφαινόνη4′- tert -βουτυλο-2′,6′-διμεθυλο-3′,5′-δινιτροακετοφαινόνη |
| English English | musk ketone 3,5-dinitro-2,6-dimethyl-4- tert -butylacetophenone4'- tert -butyl-2', 6'-dimethyl-3', 5'-dinitroacetophenone |
| French français | musc cétone 3,5-dinitro-2,6-diméthyl-4- tert -butylacétophénone4'- tert -butyl-2',6'-diméthyl-3',5'-dinitroacétophénone |
| Croatian hrvatski | mošusni keton 3,5-dinitro-2,6-dimetil-4- tert -butilacetofenon4′- tert -butil-2′,6′-dimetil-3′,5'-dinitroacetofenon |
| Italian italiano | muschio chetone 3,5-dinitro-2,6-dimetil-4- terz -butilacetofenone |
| Latvian latviešu | muskusketons 3,5-dinitro-2,6-dimetil-4- terc -butilacetofenons4'- terc -butil-2', 6'-dimetil-3',5'-dinitroacetofenons |
| Lithuanian lietuvių | muskuso ketonas 3,5-dinitro-2,6-dimetil-4- tret -butilacetofenonas4'- tret -butil-2',6'-dimetil-3',5'-dinitroacetofenonas |
| Hungarian magyar | pézsma keton 3,5-dinitro-2,6-dimetil-4- terc -butilacetofenon4'- terc -butil-2',6'-dimetil-3', 5'-dinitroacetofenon |
| Maltese Malti | keton tal-misk 3,5-dinitro-2,6-dimetil-4- tert -butilaċetofenon4'- terz -butil-2', 6'-dimetil-3', 5'-dinitroaċetofenon |
| Dutch Nederlands | muskusketon 3,5-dinitro-2,6-dimethyl-4- tert -butylacetofenon4'- tert -butyl-2', 6'-dimethyl-3',5'-dinitroacetofenon |
| Polish polski | piżmo ketonowe 3,5-dinitro-2,6-dimetylo-4- tert -butyloacetofenon4'- tert -butylo-2',6'-dimetylo-3',5'-dinitroacetofenon |
| Portuguese português | almíscar-cetona ( musk ketone ) 3,5-dinitro-2,6-dimetil-4- terc -butilacetofenona4'- terc -butil-2',6'-dimetil-3',5'-dinitroacetofenona |
| Romanian română | cetonă de mosc 3,5-dinitro-2,6-dimetil-4- terț -butilacetofenonă4'- terț -butil-2',6'-dimetil-3', 5'-dinitroacetofenonă |
| Slovak slovenčina | ketón pyžmový 3,5-dinitro-2,6-dimetyl-4- terc -butylacetofenón4'- terc -butyl-2',6'-dimetyl-3',5'-dinitroacetofenón |
| Slovenian slovenščina | mošusov keton 3,5-dinitro-2,6-dimetil-4- terc -butilacetofenon4'- terc -butil-2',6'-dimetil-3',5'-dinitroacetofenon |
| Finnish suomi | myskiketoni 3,5-dinitro-2,6-dimetyyli-4- tert -butyyliasetofenoni4’- tert -butyyli-2’,6’-dimetyyli-3’,5’-dinitroasetofenoni |
| Swedish svenska | myskketon 3,5-dinitro-2,6-dimetyl-4- tert -butylacetofenon4'- tert -butyl-2', 6'-dimetyl-3', 5'-dinitroacetofenon |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Musk ketone GHS label elements
Everything CLP Annex VI fixes for Musk ketone, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
Musk ketone
- Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Obtain special instructions before use.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF exposed or concerned:
- Get medical advice/attention.
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Musk ketone in the GHS label constructor →
07 · Physical and chemical properties
Musk ketone properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Musk ketone melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 135.5 °C (275.9 °F) | HSDB | |
| 135.5 °C (275.9 °F) | range, midpoint shown | CAMEO | |
| 135.75 °C (276.4 °F) | range, midpoint shown | HMDB |
Musk ketone density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 0.73 g/cm³ | HSDB |
Musk ketone solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Very soluble in chloroform | HSDB | |
| Insoluble (<1 mg/ml at 68.0 °F) (NTP, 1992) | at 20 °C | CAMEO | |
| In water, 0.46 mg/L at 25 °C | at 25 °C | HSDB |
Musk ketone vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 3e-7 mmHg | at 25 °C | HSDB |
Musk ketone flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 168 °C (334.4 °F) | above this value | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
08 · Handling and storage
Musk ketone storage and handling
Musk ketone storage conditions
Keep container tightly closed in a dry and well-ventilated place.
Source: Hazardous Substances Data Bank (HSDB)
Musk ketone incompatible materials
Incompatible materials: Strong acids, strong bases.
Source: Hazardous Substances Data Bank (HSDB)
Musk ketone reactivity
A nitrated ketone. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Musk ketone in the storage compatibility matrix →
09 · Questions
Musk ketone — frequently asked questions
What is the CAS number of Musk ketone?
The CAS number of Musk ketone is 81-14-1. Its EC number is 201-328-9.
What is the chemical formula of Musk ketone?
The molecular formula of Musk ketone is C14H18N2O5 and its molecular weight is 294.3 g/mol.
What does a Musk ketone label have to show?
Under CLP Annex VI the label for Musk ketone carries the pictograms Health hazard and Environment and the signal word is Warning.
Is Musk ketone flammable?
CLP Annex VI assigns Musk ketone no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 168 °C (334.4 °F), above this value (HSDB).
Is Musk ketone a carcinogen?
CLP Annex VI assigns Musk ketone H351 — suspected of causing cancer. That is category 2: the evidence points that way but is not conclusive.
What is the melting point of Musk ketone?
The melting point reported for Musk ketone is 135.5 °C (275.9 °F) (HSDB).
How should Musk ketone be stored?
Keep container tightly closed in a dry and well-ventilated place. (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Musk ketone
Keep going: substances starting with M, or search the whole database by name, CAS number, pictogram or signal word.