Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Prothioconazole

Prothioconazole is a white to light beige crystalline powder.

CAS 178928-70-6 C14H15Cl2N3OS 344.3 g/mol Warning

01 · Identification

What Prothioconazole is

Prothioconazole is a white to light beige crystalline powder. Its molecular formula is C14H15Cl2N3OS and its molecular weight is 344.3 g/mol. It boils at 587 °C, melts at 142 °C.

Under the GHS it carries the signal word Warning.

02 · Identifiers

Prothioconazole identifiers and molecular data

Prothioconazole CAS number and EC number

CAS number178928-70-6
Index number (CLP Annex VI)613-337-00-9

Prothioconazole molecular formula and molecular weight

Molecular formulaC14H15Cl2N3OS
Molecular weight344.3 g/mol

Other names for Prothioconazole

  • prothioconazole (ISO)
  • 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione

03 · GHS classification

Prothioconazole hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Prothioconazole pictograms and signal word

Signal wordWarning

Prothioconazole hazard class and category

GHS hazard classes Prothioconazole falls into
Hazard class Category From code Pictogram
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Prothioconazole hazard statements (H-codes)

Hazard statements assigned to Prothioconazole
CodeHazard statement
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Prothioconazole. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Prothioconazole

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Prothioconazole issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Prothioconazole precautionary statements

CLP Annex VI assigns 3 precautionary statements to Prothioconazole. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Prevention

What to do before and during handling so the hazard never happens.

Response

What to do once exposure, spillage or fire has already happened.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Prothioconazole name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български протиоконазол (ISO) 2-[2-хидрокси-3-(2-хлорофенил)-2-(1-хлороциклопропил)пропил]-2,4-дихидро-3 H -1,2,4-триазол-3-тион
Spanish español Protioconazol (ISO) 2-[2-(1-clorociclopropil)-3-(2-clorofenil)-2-hidroxipropil]-2,4-dihidro-3 H -1,2,4-triazol-3-tiona
Czech čeština prothiokonazol (ISO) 2-[2-(1-chlorcyklopropyl)-3-(2-chlorfenyl)-2-hydroxypropyl]-2,4-dihydro-3 H -1,2,4-triazol-3-thion
Danish dansk prothioconazol (ISO) 2-[2-(1-chlorcyclopropyl)-3-(2-chlorphenyl)-2-hydroxypropyl]-2,4-dihydro-3 H -1,2,4-triazol-3-thion
German Deutsch Prothioconazol (ISO) 2-[2-(1-Chlorcyclopropyl)-3-(2-chlorphenyl)-2-hydroxypropyl]-2,4-dihydro-3 H -1,2,4-triazol-3-thion
Estonian eesti protiokonasool (ISO) 2-[2-(1-klorotsüklopropüül)-3-(2-klorofenüül)-2-hüdroksüpropüül]-2,4-dihüdro-3 H -1,2,4-triasool-3-tioon
Greek ελληνικά rothioconazole (προθειοκοναζόλη) (ISO) 2-[2-(1-χλωροκυκλοπροπυλο)-3-(2-χλωροφαινυλ)-2-υδροξυπροπυλο]-2,4-διυδρο-3 H 1,2,4-τριαζολο-3-θειόνη
English English prothioconazole (ISO) 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3 H -1,2,4-triazole-3-thione
French français prothioconazole (ISO) 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophényl)-2-hydroxypropyl]-2,4-dihydro-3 H -1,2,4-triazole-3-thione
Croatian hrvatski protiokonazol (ISO) 2-[2-(1-klorciklopropi)-3-(2-klorofenil)-2-hidroksipropil]-2,4-dihidro-3 H -1,2,4-triazol-3-thion
Italian italiano protioconazolo (ISO) 2-[2-(1-clorociclopropil)-3-(2-clorofenil)-2-idrossipropil]-2,4-diidro-3 H -1,2,4-triazolo-3-tione
Latvian latviešu protiokonazols (ISO) 2-[2-(1-hlorciklopropil)-3-(2-hlorfenil)-2-hidroksipropil]-2,4-dihidro-3 H -1,2,4-triazol-3-tions
Lithuanian lietuvių protiokonazolas (ISO) 2-[2-(1-chlorciklopropil)-3-(2-chlorfenil)-2-hidroksipropil]-2,4-dihidro-3 H -1,2,4-triazol-3-tionas
Hungarian magyar protiokonazol (ISO) 2-[2-(1-klórciklopropil)-3-(2-klórfenil)-2-hidroxipropil]-2,4-dihidro-3 H -1,2,4-triazol-3-tion
Maltese Malti protijokonażol (ISO) 2-[2-(1-kloroċiklopropil)-3-(2-klorofenil)-2-idrossipropil]-2,4-diidro-3 H -1,2,4-triażol-3-tijon
Dutch Nederlands prothioconazool (ISO) 2-[2-(1-chloorcyclopropyl)-3-(2-chloorfenyl)-2-hydroxypropyl]-2,4-dihydro-3 H -1,2,4-triazool-3-thion
Polish polski protiokonazol (ISO) 2-[2-(1-chlorocyklopropylo)-3-(2-chlorofenylo)-2-hydroksypropylo]-2,4-dihydro-3 H -1,2,4-triazolo-3-tion
Portuguese português protioconazole (ISO) 2-[2-(1-clorociclopropil)-3-(2-clorofenil)-2-hidroxipropil]-2,4-di-hidro-3 H -1,2,4-triazolo-3-tiona
Romanian română protioconazol (ISO) 2-[2-(1-clorociclopropil)-3-(2-clorofenil)-2-hidroxipropil]-2,4-dihidro-3 H -1,2,4-triazol-3-tionă
Slovak slovenčina protiokonazol (ISO), ( RS )-2-[2-(1-chlórcyklopropyl)-3-(2-chlórfenyl)-2-hydroxypropyl]-2,4-dihydro-1,2,4-triazol-3-tión
Slovenian slovenščina protiokonazol (ISO) 2-[2-(1-klorociklopropil)-3-(2-klorofenil)-2-hidroksipropil]-2,4-dihidro-3 H -1,2,4-triazol-3-tion
Finnish suomi protiokonatsoli (ISO) 2-[2-(1-kloorisyklopropyyli)-3-(2-kloorifenyyli)-2-hydroksipropyyli]-2,4-dihydro-3 H -1,2,4-triatsoli-3-tioni
Swedish svenska protiokonazol (ISO) 2-[2-(1-klorcyklopropyl)-3-(2-klorfenyl)-2-hydroxipropyl]-2,4-dihydro-3 H -1,2,4-triazol-3-tion

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Prothioconazole GHS label elements

Everything CLP Annex VI fixes for Prothioconazole, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS09 Environment pictogram

Warning

Prothioconazole

  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Avoid release to the environment.
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Prothioconazole in the GHS label constructor →

07 · Health hazards

Prothioconazole health hazards and exposure limits

Prothioconazole carcinogenicity classification

The available studies in the mouse and rat show no increase in tumor incidence. Therefore, the Health Effects Division /of the USEPA/ has concluded prothioconazole or its metabolites are not carcinogenic, and are classified "Not likely to be Carcinogenic to Humans" according to the 2005 Cancer Guidelines.

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

08 · Physical and chemical properties

Prothioconazole properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Prothioconazole boiling point

Property Value Conditions Source
Boiling point 587 °C (1088.6 °F) calc HSDB

Prothioconazole melting point

Property Value Conditions Source
Melting point 141.8 °C (287.2 °F) range, midpoint shown HSDB

Prothioconazole density

Property Value Conditions Source
Density 1.36 g/cm³ at 20 °C HSDB

Prothioconazole solubility

Property Value Conditions Source
Solubility In water, 300 mg/L at 20 °C at 20 °C HSDB

Prothioconazole vapor pressure

Property Value Conditions Source
Vapor pressure 3e-7 mmHg below this value, at 20 °C HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Source notes

Further notes on Prothioconazole

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Solubility

In n-hexane <0.1, xylene 8, n-octanol 58, isopropanol 87, acetonitrile 69, DMSO 126, dichloromethane 88, ethyl acetate, polyethylene glycol and acetone all >250 (all in g/L, 20 °C)

Source: HSDB

10 · Handling and storage

Prothioconazole storage and handling

Prothioconazole storage conditions

Store in a cool, dry place and in such a manner as to prevent cross contamination with other pesticides, fertilizers, food, and feed. Store in original container and out of the reach of children, preferably in a locked storage area. Handle and open container in a manner as to prevent spillage./Proline 480 SC Fungicide/

Source: Hazardous Substances Data Bank (HSDB)

Planning storage for a mix of chemicals? Check Prothioconazole in the storage compatibility matrix →

11 · Questions

Prothioconazole — frequently asked questions

What is the CAS number of Prothioconazole?

The CAS number of Prothioconazole is 178928-70-6.

What is the chemical formula of Prothioconazole?

The molecular formula of Prothioconazole is C14H15Cl2N3OS and its molecular weight is 344.3 g/mol.

What does a Prothioconazole label have to show?

Under CLP Annex VI the label for Prothioconazole carries the pictogram Environment and the signal word is Warning.

Is Prothioconazole flammable?

CLP Annex VI assigns Prothioconazole no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is Prothioconazole a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Prothioconazole. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of Prothioconazole?

The boiling point reported for Prothioconazole is 587 °C (1088.6 °F), calc (HSDB).

What is the melting point of Prothioconazole?

The melting point reported for Prothioconazole is 141.8 °C (287.2 °F), range, midpoint shown (HSDB).

How should Prothioconazole be stored?

Store in a cool, dry place and in such a manner as to prevent cross contamination with other pesticides, fertilizers, food, and feed. Store in original container and out of the reach of children, preferably in a locked storage area. Handle and open container in a manner as to prevent spillage./Proline 480 SC Fungicide/ (Hazardous Substances Data Bank (HSDB))

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