Substance profile
Quinolin-8-ol
Quinolin-8-ol is white crystals or white crystalline powder with a phenolic odor.
01 · Identification
What Quinolin-8-ol is
Quinolin-8-ol is white crystals or white crystalline powder with a phenolic odor. Its molecular formula is C9H7NO and its molecular weight is 145.16 g/mol. It boils at 267 °C, melts at 76.1 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Quinolin-8-ol identifiers and molecular data
Quinolin-8-ol CAS number and EC number
Quinolin-8-ol molecular formula and molecular weight
Other names for Quinolin-8-ol
- 8-hydroxyquinoline
03 · GHS classification
Quinolin-8-ol hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Quinolin-8-ol pictograms and signal word
Quinolin-8-ol hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 3 | H301 | GHS06 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 1 | H318 | GHS05 |
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Quinolin-8-ol hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H360D | May damage the unborn child. |
| H301 | Toxic if swallowed. |
| H318 | Causes serious eye damage. |
| H317 | May cause an allergic skin reaction. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Quinolin-8-ol. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Quinolin-8-ol
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Quinolin-8-ol issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Quinolin-8-ol precautionary statements
CLP Annex VI assigns 14 precautionary statements to Quinolin-8-ol. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Quinolin-8-ol name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | хинолин-8-ол 8-хидроксихинолин |
| Spanish español | Quinolin-8-ol 8-hidroxiquinoleína |
| Czech čeština | chinolin-8-ol 8-hydroxychinolin |
| Danish dansk | quinolin-8-ol 8-hydroxyquinolin |
| German Deutsch | Chinolin-8-ol 8-Hydroxychinolin |
| Estonian eesti | kinoliin-8-ool 8-hüdroksükinoliin |
| Greek ελληνικά | κινολιν-8-όλη 8-υδροξυκινολίνη |
| English English | quinolin-8-ol 8-hydroxyquinoline |
| French français | quinoléine-8-ol 8-hydroxyquinoléine |
| Croatian hrvatski | kinolin-8-ol 8-hidroksikinolin |
| Italian italiano | chinolin-8-olo 8-idrossichinolina |
| Latvian latviešu | hinolīn-8-ols 8-hidroksihinolīns |
| Lithuanian lietuvių | chinolin-8-olis 8-hidroksichinolinas |
| Hungarian magyar | kinolin-8-ol 8-hidroxikinolin |
| Maltese Malti | kwinolin-8-ol 8-idrossikwinolina |
| Dutch Nederlands | chinoline-8-ol 8-hydroxychinoline |
| Polish polski | chinolin-8-ol 8-hydroksychinolina |
| Portuguese português | Quinolin-8-ol 8-hidroxiquinolina |
| Romanian română | 8-chinolinol 8-hidroxichinolină |
| Slovak slovenčina | chinolín-8-ol 8-hydroxychinolín |
| Slovenian slovenščina | kinolin-8-ol 8-hidroksikinolin |
| Finnish suomi | kinolin-8-oli 8-hydroksikinoliini |
| Swedish svenska | kinolin-8-ol 8-hydroxikinolin |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Quinolin-8-ol GHS label elements
Everything CLP Annex VI fixes for Quinolin-8-ol, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Quinolin-8-ol
- May damage the unborn child.
- Toxic if swallowed.
- Causes serious eye damage.
- May cause an allergic skin reaction.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Contaminated work clothing should not be allowed out of the workplace.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF IN EYES:
- Immediately call a POISON CENTER/doctor/…
- Get medical advice/attention.
- Rinse mouth.
- If skin irritation or rash occurs:
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Quinolin-8-ol in the GHS label constructor →
07 · Health hazards
Quinolin-8-ol health hazards and exposure limits
Quinolin-8-ol carcinogenicity classification
Under the conditions of these studies, there was no evidence of carcinogenicity for male and female F344/N rats or for male and female B6C3F1 mice given 8-hydroxyquinoline in feed at concentrations of 1,500 or 3,000 ppm for 103 weeks.
Source: US National Toxicology Program · TR-276: Toxicology and Carcinogenesis Studies of 8-Hydroxyquinoline (CASRN 148-24-3) in F344/N Rats and B6C3F1 Mice (Feed Studies) (1985 )
No data are available in humans. Inadequate evidence of carcinogenicity in animals. OVERALL EVALUATION: Group 3: The agent is not classifiable as to its carcinogenicity to humans.
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
Quinolin-8-ol properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Quinolin-8-ol boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 267.22 °C (513 °F) | at 760 mmHg | CAMEO |
| 267 °C (512.6 °F) | at 760 mmHg | DOE PAC | |
| 267 °C (512.6 °F) | approximate | HSDB |
Quinolin-8-ol melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 76.11 °C (169 °F) | CAMEO | |
| 76 °C (168.8 °F) | DOE PAC | ||
| 74 °C (165.2 °F) | range, midpoint shown | HSDB |
Quinolin-8-ol density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.034 g/cm³ | at 20 °C | HSDB |
| 1.034 g/cm³ | at 208.89 °C | CAMEO |
Quinolin-8-ol solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Soluble in alcohol, acetone, chloroform, benzene, and in formic, acetic, hydrochloric, and sulfuric acids and alkalies. | HSDB | |
| 1 part in 1500 parts water | HSDB | ||
| In water, 556 mg/l @ 20 °C | at 20 °C | HSDB |
Quinolin-8-ol vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.0017 mmHg | at 25 °C | HSDB |
| 0.0016 mmHg | Haz-Map |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
Quinolin-8-ol fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Quinolin-8-ol fire potential
Combustible when exposed to heat or flame.
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
Quinolin-8-ol storage and handling
Quinolin-8-ol reactivity
8-HYDROXYQUINOLINE darkens on exposure to light. This chemical readily forms stable metal chelates. It is incompatible with strong oxidizers. It is also incompatible with many metal ions. (NTP, 1992)
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Quinolin-8-ol in the storage compatibility matrix →
11 · Questions
Quinolin-8-ol — frequently asked questions
What is the CAS number of Quinolin-8-ol?
The CAS number of Quinolin-8-ol is 148-24-3. Its EC number is 205-711-1.
What is the chemical formula of Quinolin-8-ol?
The molecular formula of Quinolin-8-ol is C9H7NO and its molecular weight is 145.16 g/mol.
What does a Quinolin-8-ol label have to show?
Under CLP Annex VI the label for Quinolin-8-ol carries the pictograms Health hazard, Skull and crossbones, Corrosion and Environment and the signal word is Danger.
Is Quinolin-8-ol flammable?
CLP Annex VI assigns Quinolin-8-ol no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Quinolin-8-ol a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Quinolin-8-ol. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health. IARC places it in Group 3: not classifiable as to its carcinogenicity to humans.
What is the boiling point of Quinolin-8-ol?
The boiling point reported for Quinolin-8-ol is 267.22 °C (513 °F), at 760 mmHg (CAMEO).
What is the melting point of Quinolin-8-ol?
The melting point reported for Quinolin-8-ol is 76.11 °C (169 °F) (CAMEO).
Nearby
Substances next to Quinolin-8-ol
Keep going: substances starting with Q, or search the whole database by name, CAS number, pictogram or signal word.