Substance profile
(R)-p-mentha-1,8-diene
(R)-p-mentha-1,8-diene is an oil with a citrus odor.
01 · Identification
What (R)-p-mentha-1,8-diene is
(R)-p-mentha-1,8-diene is an oil with a citrus odor. Its molecular formula is C10H16 and its molecular weight is 136.23 g/mol. It boils at 178 °C, melts at -74 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
(R)-p-mentha-1,8-diene identifiers and molecular data
(R)-p-mentha-1,8-diene CAS number and EC number
(R)-p-mentha-1,8-diene molecular formula and molecular weight
Other names for (R)-p-mentha-1,8-diene
- d-limonene
03 · GHS classification
(R)-p-mentha-1,8-diene hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
(R)-p-mentha-1,8-diene pictograms and signal word
(R)-p-mentha-1,8-diene hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Flammable liquids GHS chapter 2.6 | Category 3 | H226 | GHS02 |
| Skin corrosion/irritation GHS chapter 3.2 | Category 2 | H315 | GHS07 |
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
| Aspiration hazard GHS chapter 3.10 | Category 1 | H304 | GHS08 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 3 | H412 | — |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
(R)-p-mentha-1,8-diene hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H226 | Flammable liquid and vapour. |
| H304 | May be fatal if swallowed and enters airways. |
| H315 | Causes skin irritation. |
| H317 | May cause an allergic skin reaction. |
| H400 | Very toxic to aquatic life. |
| H412 | Harmful to aquatic life with long lasting effects. |
This page lists only the codes assigned to (R)-p-mentha-1,8-diene. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for (R)-p-mentha-1,8-diene
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of (R)-p-mentha-1,8-diene issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
(R)-p-mentha-1,8-diene precautionary statements
CLP Annex VI assigns 17 precautionary statements to (R)-p-mentha-1,8-diene. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
(R)-p-mentha-1,8-diene name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | ( R )- p -мента-1,8-диен d-лимонен |
| Spanish español | ( R )- p -Menta-1,8-dieno d-limoneno |
| Czech čeština | ( R )- p -mentha-1,8-dien d-limonen |
| Danish dansk | ( R )- p -mentha-1,8-dien d-limonen |
| German Deutsch | ( R )- p -Mentha-1,8-dien d-Limonen |
| Estonian eesti | ( R )- p -menta-1,8-dieen D-limoneen |
| Greek ελληνικά | ( R )- p -mentha-1,8-diene d-limonene |
| English English | ( R )- p -mentha-1,8-diene d-limonene |
| French français | ( R )- p -mentha-1,8-diène d-limonène |
| Croatian hrvatski | ( R )- p -menta-1,8-dien d-limonen |
| Italian italiano | ( R )- p -menta-1,8-diene d-limonene |
| Latvian latviešu | ( R )- p -menta-1,8-diēns d -limonēns |
| Lithuanian lietuvių | ( R )- p -menta-1,8-dienas d-limonenas |
| Hungarian magyar | ( R )- p -menta-1,8-dién d-limonén |
| Maltese Malti | ( R )- p -menta-1,8-dien d-limonen |
| Dutch Nederlands | ( R )- p -mentha-1,8-diene d-limonene |
| Polish polski | ( R )- p -menta-1,8-dien d-limonen |
| Portuguese português | ( R )- p -menta-1,8-dieno D-limoneno |
| Romanian română | ( R )- p -menta-1,8-dienă d-limonen |
| Slovak slovenčina | ( R )-1-metyl-4-(1-metyletenyl)cyklohexén, d-limonén |
| Slovenian slovenščina | ( R )- p -menta-1,8-dien d-limonen |
| Finnish suomi | ( R )- p -menta-1,8-dieeni d-limoneeni |
| Swedish svenska | ( R )- p -menta-1,8-dien d-limonen |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
(R)-p-mentha-1,8-diene GHS label elements
Everything CLP Annex VI fixes for (R)-p-mentha-1,8-diene, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
(R)-p-mentha-1,8-diene
- Flammable liquid and vapour.
- May be fatal if swallowed and enters airways.
- Causes skin irritation.
- May cause an allergic skin reaction.
- Very toxic to aquatic life.
- Harmful to aquatic life with long lasting effects.
- Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- Keep container tightly closed.
- Use explosion-proof [electrical/ventilating/lighting/…] equipment.
- Use only non-sparking tools.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Wash … thoroughly after handling.
- Contaminated work clothing should not be allowed out of the workplace.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF ON SKIN:
- Get medical advice/attention.
- If skin irritation occurs:
- If skin irritation or rash occurs:
- Wash with plenty of water/…
- Collect spillage.
- Store in a well-ventilated place.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open (R)-p-mentha-1,8-diene in the GHS label constructor →
07 · Health hazards
(R)-p-mentha-1,8-diene health hazards and exposure limits
(R)-p-mentha-1,8-diene hazard summary
d-Limonene is a liquid with a pleasant lemon-like odor. It is used as a solvent to replace chlorinated hydrocarbons and other more volatile and toxic organic solvents. It readily oxidizes when in contact with air. The oxidized form of d-limonene is a known skin sensitizer. [HSDB] A skin and eye irritant that may cause skin sensitization; [ICSC] The racemic mixture of d-limonene and l-limonene is called limonene or dipentene (138-86-3). [Kanerva, p. 1789] Estimated lethal dose orally for humans is 0.5 to 5 g/kg; Healthy men had diarrhea after an oral dose of 20 grams; Liver effects were noted in a chronic high-dose feeding study of mice; [AIHA] See Limonene and l-Limonene.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
(R)-p-mentha-1,8-diene carcinogenicity classification
Under the conditions of these 2-year gavage studies, there was clear evidence of carcinogenic activity of d-limonene for male F344/N rats, as shown by increased incidences of tubular cell hyperplasia, adenomas, and adenocarcinomas of the kidney. There was no evidence of carcinogenic activity of d-limonene for female F344/N rats that received 300 or 600 mg/kg. There was no evidence of carcinogenic activity of d-limonene for male B6C3F1 mice that received 250 or 500 mg/kg. There was no evidence of carcinogenic activity of d-limonene for female B6C3F1 mice that received 500 or 1,000 mg/kg.
Source: US National Toxicology Program · TR-347: Toxicology and Carcinogenesis Studies of d-Limonene (CASRN 5989-27-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies) (1990 )
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
(R)-p-mentha-1,8-diene properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
(R)-p-mentha-1,8-diene boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 177.6 °C (351.7 °F) | HSDB | |
| 178 °C (352.4 °F) | ICSC | ||
| 178 °C (352.4 °F) | at 760 mmHg | DOE PAC |
(R)-p-mentha-1,8-diene melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -74 °C (-101.2 °F) | HSDB | |
| -96.89 °C (-142.4 °F) | CAMEO |
(R)-p-mentha-1,8-diene density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 0.84 g/cm³ | ICSC | |
| 0.8411 g/cm³ | at 20 °C | HSDB |
(R)-p-mentha-1,8-diene solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Miscible with ethanol and ether; soluble in carbon tetrachloride | HSDB | |
| Miscible with fixed oils; slightly soluble in glycerin; insoluble in propylene glycol | HSDB | ||
| In water, 13.8 mg/L at 25 °C | at 25 °C | HSDB |
(R)-p-mentha-1,8-diene vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 1.4251 mmHg | at 20 °C | ICSC |
| 1.98 mmHg | at 25 °C | HSDB |
(R)-p-mentha-1,8-diene flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 48 °C (118.4 °F) | closed cup | HSDB |
| 48.33 °C (119 °F) | CAMEO | ||
| 48 °C (118.4 °F) | ICSC |
(R)-p-mentha-1,8-diene autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 237 °C (458.6 °F) | HSDB |
(R)-p-mentha-1,8-diene lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | 0.7 % by volume | at 150 °C | CAMEO |
(R)-p-mentha-1,8-diene upper explosive limit (UEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Upper explosive limit (UEL) | 6 % by volume | HSDB | |
| 6.1 % by volume | at 150 °C | CAMEO |
(R)-p-mentha-1,8-diene vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 4.7 (air = 1) | HSDB | |
| 4.69 (air = 1) | CAMEO |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
(R)-p-mentha-1,8-diene fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
(R)-p-mentha-1,8-diene fire potential
Flammable
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
(R)-p-mentha-1,8-diene storage and handling
(R)-p-mentha-1,8-diene peroxide formation
D*: Other compounds that may form peroxides
Source: Lab and Research Safety, University of Minnesota
(R)-p-mentha-1,8-diene safe storage
Fireproof. Separated from strong oxidants. Store in an area without drain or sewer access.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
(R)-p-mentha-1,8-diene storage conditions
Fireproof. Separated from strong oxidants. Store in an area without drain or sewer access.
Source: Hazardous Substances Data Bank (HSDB)
(R)-p-mentha-1,8-diene incompatible materials
Reacts violently with a mixture of iodine pentafluoride and tetrafluoroethylene, causing fire and explosion hazard. Reacts with oxidants.
Source: Hazardous Substances Data Bank (HSDB)
(R)-p-mentha-1,8-diene reactivity
D-LIMONENE is sensitive to exposure to light. Atmospheric oxidation can occur. This chemical is incompatible with strong oxidizing agents. It reacts violently with (iodine pentafluoride + tetrafluoroethylene). With dry hydrogen chloride or hydrogen bromide, it forms monohalides. With aqueous hydrogen chloride or hydrogen bromide, it forms the dihalide. (NTP, 1992)
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check (R)-p-mentha-1,8-diene in the storage compatibility matrix →
11 · Questions
(R)-p-mentha-1,8-diene — frequently asked questions
What is the CAS number of (R)-p-mentha-1,8-diene?
The CAS number of (R)-p-mentha-1,8-diene is 5989-27-5. Its EC number is 227-813-5.
What is the chemical formula of (R)-p-mentha-1,8-diene?
The molecular formula of (R)-p-mentha-1,8-diene is C10H16 and its molecular weight is 136.23 g/mol.
What does a (R)-p-mentha-1,8-diene label have to show?
Under CLP Annex VI the label for (R)-p-mentha-1,8-diene carries the pictograms Flame, Exclamation mark, Health hazard and Environment and the signal word is Danger.
Is (R)-p-mentha-1,8-diene flammable?
Yes. CLP Annex VI assigns (R)-p-mentha-1,8-diene H226 — flammable liquid and vapour. The flash point reported for it is 48 °C (118.4 °F), closed cup (HSDB).
Is (R)-p-mentha-1,8-diene a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for (R)-p-mentha-1,8-diene. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health. IARC places it in Group 3: not classifiable as to its carcinogenicity to humans.
What is the boiling point of (R)-p-mentha-1,8-diene?
The boiling point reported for (R)-p-mentha-1,8-diene is 177.6 °C (351.7 °F) (HSDB).
What is the melting point of (R)-p-mentha-1,8-diene?
The melting point reported for (R)-p-mentha-1,8-diene is -74 °C (-101.2 °F) (HSDB).
How should (R)-p-mentha-1,8-diene be stored?
CLP Annex VI assigns (R)-p-mentha-1,8-diene the storage statement P403. Fireproof. Separated from strong oxidants. Store in an area without drain or sewer access. (Hazardous Substances Data Bank (HSDB))
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