Substance profile
Succinic anhydride
Succinic anhydride is needles from alc; rhombic pyramids from chloroform or carbon tetrachloride and is odorless.
01 · Identification
What Succinic anhydride is
Succinic anhydride is needles from alc; rhombic pyramids from chloroform or carbon tetrachloride and is odorless. Its molecular formula is C4H4O3 and its molecular weight is 100.07 g/mol. It boils at 261 °C, melts at 120 °C, is practically insoluble in water.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Succinic anhydride identifiers and molecular data
Succinic anhydride CAS number and EC number
Succinic anhydride molecular formula and molecular weight
03 · GHS classification
Succinic anhydride hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Succinic anhydride pictograms and signal word
Succinic anhydride hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
| Skin corrosion/irritation GHS chapter 3.2 | Category 1A or 1B or 1C | H314 | GHS05 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 1 | H318 | GHS05 |
| Respiratory sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H334 | GHS08 |
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Succinic anhydride hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H302 | Harmful if swallowed. |
| H314 | Causes severe skin burns and eye damage. |
| H318 | Causes serious eye damage. |
| H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| H317 | May cause an allergic skin reaction. |
Succinic anhydride supplemental EU statements (EUH)
| Code | Statement |
|---|---|
| EUH071 | Corrosive to the respiratory tract. |
This page lists only the codes assigned to Succinic anhydride. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Succinic anhydride
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Succinic anhydride issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Succinic anhydride precautionary statements
CLP Annex VI assigns 14 precautionary statements to Succinic anhydride. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Succinic anhydride name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | янтарен анхидрид |
| Spanish español | Anhídrido succínico |
| Czech čeština | sukcinanhydrid |
| Danish dansk | ravsyreanhydrid |
| German Deutsch | Bernsteinsäureanhydrid |
| Estonian eesti | suktsiinanhüdriid |
| Greek ελληνικά | ηλεκτρικός ανυδρίτης |
| English English | succinic anhydride |
| French français | anhydride succinique |
| Croatian hrvatski | anhidrid jantarne kiseline |
| Italian italiano | Anidride succinica |
| Latvian latviešu | dzintarskābes anhidrīds |
| Lithuanian lietuvių | gintaro rūgšties anhidridas |
| Hungarian magyar | borostyánkősav-anhidrid |
| Maltese Malti | anidride suċċiniku |
| Dutch Nederlands | barnsteenzuuranhydride |
| Polish polski | bezwodnik bursztynowy |
| Portuguese português | anidrido succínico |
| Romanian română | anhidridă succinică |
| Slovak slovenčina | anhydrid kyseliny jantárovej |
| Slovenian slovenščina | anhidrid sukcinske kisline |
| Finnish suomi | meripihkahappoanhydridi |
| Swedish svenska | bärnstenssyraanhydrid |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Succinic anhydride GHS label elements
Everything CLP Annex VI fixes for Succinic anhydride, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Succinic anhydride
- Harmful if swallowed.
- Causes severe skin burns and eye damage.
- Causes serious eye damage.
- May cause allergy or asthma symptoms or breathing difficulties if inhaled.
- May cause an allergic skin reaction.
- Corrosive to the respiratory tract.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Contaminated work clothing should not be allowed out of the workplace.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF IN EYES:
- Immediately call a POISON CENTER/doctor/…
- Call a POISON CENTER/doctor/… if you feel unwell.
- Get medical advice/attention.
- Rinse mouth.
- Do NOT induce vomiting.
- If skin irritation or rash occurs:
- Remove contact lenses, if present and easy to do. Continue rinsing.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Succinic anhydride in the GHS label constructor →
07 · Health hazards
Succinic anhydride health hazards and exposure limits
Succinic anhydride hazard summary
A skin, eye, and respiratory tract irritant; [HSDB] May cause blisters and burns to skin; [CAMEO] The substance is severely irritating to the eyes and is irritating to the respiratory tract. [ICSC] An irritant (severe to eyes); [MSDSonline] See ACID ANHYDRIDES.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Succinic anhydride carcinogenicity classification
Under the conditions of these 2-year studies, there was no evidence of carcinogenic activity of succinic anhydride for male or female F344/N rats given 50 or 100 mg/kg succinic anhydride. There was no evidence of carcinogenic activity for male B6C3F1 mice given 38 or 75 mg/kg succinic anhydride or for female B6C3F1 mice given 75 or 150 mg/kg.
Source: US National Toxicology Program · TR-373: Toxicology and Carcinogenesis Studies of Succinic Anhydride (CASRN 108-30-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies) (1990 )
No data are available in humans. Limited evidence of carcinogenicity in animals. OVERALL EVALUATION: Group 3: The agent is not classifiable as to its carcinogenicity to humans.
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
Succinic anhydride properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Succinic anhydride boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 261 °C (501.8 °F) | at 760 mmHg | HSDB |
| 261.11 °C (502 °F) | at 760 mmHg | CAMEO | |
| 261 °C (501.8 °F) | ICSC |
Succinic anhydride melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 119.6 °C (247.3 °F) | HSDB | |
| 119.61 °C (247.3 °F) | CAMEO |
Succinic anhydride density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.503 g/cm³ | also given as 1.104 and 1.234 | HSDB |
| 0.7561 g/cm³ | HSDB | ||
| 1.234 g/cm³ | at 20 °C | CAMEO |
Succinic anhydride solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Insoluble in water | HSDB | |
| Soluble in chloroform, carbon tetrachloride, alcohol; very slightly soluble in ether and water. | HSDB | ||
| IN ETHANOL AT 25 °C: 2.56 G/100 ML; IN ETHER AT 25 °C: 0.64 G/100 ML; IN CHLOROFORM AT 25 °C: 0.87 G/100 ML | at 25 °C | HSDB |
Succinic anhydride vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.0015 mmHg | at 25 °C | HSDB |
| 1 mmHg | at 92 °C | HSDB |
Succinic anhydride flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 157 °C (314.6 °F) | ICSC |
Succinic anhydride vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 3.7 (air = 1) | CAMEO | |
| 3.45 (air = 1) | ICSC |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
Succinic anhydride fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Succinic anhydride fire potential
Combustible
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
Succinic anhydride storage and handling
Succinic anhydride incompatible materials
Succinic anhydride is dimerized to 1,6-dioxaspiro[4.4]nonane-2,7dione by heating with sodium hydroxide.
Source: Hazardous Substances Data Bank (HSDB)
Succinic anhydride reactivity
SUCCINIC ANHYDRIDE reacts exothermically with water. Reactions are usually slow, but might become violent if local heating accelerates their rate. Acids accelerate the reaction with water. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Succinic anhydride in the storage compatibility matrix →
11 · Questions
Succinic anhydride — frequently asked questions
What is the CAS number of Succinic anhydride?
The CAS number of Succinic anhydride is 108-30-5. Its EC number is 203-570-0.
What is the chemical formula of Succinic anhydride?
The molecular formula of Succinic anhydride is C4H4O3 and its molecular weight is 100.07 g/mol.
What does a Succinic anhydride label have to show?
Under CLP Annex VI the label for Succinic anhydride carries the pictograms Exclamation mark, Corrosion and Health hazard and the signal word is Danger.
Is Succinic anhydride flammable?
CLP Annex VI assigns Succinic anhydride no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 157 °C (314.6 °F) (ICSC).
Is Succinic anhydride a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Succinic anhydride. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health. IARC places it in Group 3: not classifiable as to its carcinogenicity to humans.
What is the boiling point of Succinic anhydride?
The boiling point reported for Succinic anhydride is 261 °C (501.8 °F), at 760 mmHg (HSDB).
What is the melting point of Succinic anhydride?
The melting point reported for Succinic anhydride is 119.6 °C (247.3 °F) (HSDB).
Nearby
Substances next to Succinic anhydride
Keep going: substances starting with S, or search the whole database by name, CAS number, pictogram or signal word.