Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

TCA-sodium (ISO)

TCA-sodium (ISO) is a yellow powder.

CAS 650-51-1 C2Cl3NaO2 185.36 g/mol Warning

01 · Identification

What TCA-sodium (ISO) is

TCA-sodium (ISO) is a yellow powder. Its molecular formula is C2Cl3NaO2 and its molecular weight is 185.36 g/mol. It melts at 183 °C.

Under the GHS it carries the signal word Warning.

02 · Identifiers

TCA-sodium (ISO) identifiers and molecular data

TCA-sodium (ISO) CAS number and EC number

CAS number650-51-1
EC number211-479-2
Index number (CLP Annex VI)607-005-00-2

TCA-sodium (ISO) molecular formula and molecular weight

Molecular formulaC2Cl3NaO2
Molecular weight185.36 g/mol

Other names for TCA-sodium (ISO)

  • sodium trichloroacetate

03 · GHS classification

TCA-sodium (ISO) hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

TCA-sodium (ISO) pictograms and signal word

Signal wordWarning

TCA-sodium (ISO) hazard class and category

GHS hazard classes TCA-sodium (ISO) falls into
Hazard class Category From code Pictogram
Specific target organ toxicity - single exposure GHS chapter 3.8 Category 3 H335 GHS07
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

TCA-sodium (ISO) hazard statements (H-codes)

Hazard statements assigned to TCA-sodium (ISO)
CodeHazard statement
H335 May cause respiratory irritation.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to TCA-sodium (ISO). The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for TCA-sodium (ISO)

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of TCA-sodium (ISO) issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

TCA-sodium (ISO) precautionary statements

CLP Annex VI assigns 3 precautionary statements to TCA-sodium (ISO). They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Prevention

What to do before and during handling so the hazard never happens.

Response

What to do once exposure, spillage or fire has already happened.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

TCA-sodium (ISO) name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български TCA-натрий (ISO) натриев трихлороацетат
Spanish español TCA-sodio (ISO) tricloroacetato de sodio
Czech čeština TCA-natrium (ISO) trichloroctan sodný
Danish dansk TCA-Na (ISO) natriumtrichloracetat
German Deutsch TCA-Natrium (ISO) NatriumtrichloracetatTrichloressigsäure, Natriumsalz
Estonian eesti TCA-naatrium (ISO) naatriumtrikloroatsetaat
Greek ελληνικά TCA-sodium (νατριούχο TCA) (ISO) τριχλωροξικό νάτριο
English English TCA-sodium (ISO) sodium trichloroacetate
French français TCA-sodium (ISO) trichloroacétate de sodium
Croatian hrvatski TCA-natrij (ISO) natrijev trikloracetat
Italian italiano TCA sodio (ISO) tricloroacetato di sodio
Latvian latviešu TCA-nātrijs (ISO) nātrija trihloracetāts
Lithuanian lietuvių natrio TCA (ISO) natrio trichloracetatas
Hungarian magyar TCA-nátrium (ISO) nátrium-triklóracetát
Maltese Malti TCA-sodju (ISO) trikloroaċetat tas-sodju
Dutch Nederlands TCA-natrium (ISO) natriumtrichlooracetaat
Polish polski TCA sodu (ISO) trichlorooctan sodu
Portuguese português TCA-sódio (ISO) tricloroacetato de sódio
Romanian română TCA-sodium (ISO) tricloroacetat de sodiu
Slovak slovenčina TCA-nátrium (ISO) nátrium-trichlóracetát
Slovenian slovenščina TCA-natrij (ISO) natrijev trikloroacetat
Finnish suomi TCA-natrium (ISO) natriumtriklooriasetaatti
Swedish svenska TCA-natrium (ISO) natriumtrikloracetat

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

TCA-sodium (ISO) GHS label elements

Everything CLP Annex VI fixes for TCA-sodium (ISO), laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS07 Exclamation mark pictogramGHS09 Environment pictogram

Warning

TCA-sodium (ISO)

  • May cause respiratory irritation.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Avoid release to the environment.
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open TCA-sodium (ISO) in the GHS label constructor →

07 · Health hazards

TCA-sodium (ISO) health hazards and exposure limits

TCA-sodium (ISO) hazard summary

A skin, eye, and respiratory tract irritant; [ICSC] A strong nose and throat irritant; [HSDB] A respiratory tract irritant; [eChemPortal: ESIS] An irritant; [MSDSonline] The ACGIH profile is for Trichloroacetic acid (76-03-9) and the sodium salt (650-51-1). See Trichloroacetic acid.

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

TCA-sodium (ISO) carcinogenicity classification

Classification of carcinogenicity: 1) evidence in humans: inadequate; 2) evidence in animals: limited. Overall summary evaluation of carcinogenic risk to humans is Group 3: The agent is not classifiable as to its carcinogenicity to humans. /From table; Trichloroacetic acid/

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

08 · Physical and chemical properties

TCA-sodium (ISO) properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

TCA-sodium (ISO) melting point

Property Value Conditions Source
Melting point 182.5 °C (360.5 °F) range, midpoint shown HSDB

TCA-sodium (ISO) density

Property Value Conditions Source
Density 0.9 g/cm³ ICSC

TCA-sodium (ISO) solubility

Property Value Conditions Source
Solubility Soluble in ethanol HSDB
In water = 1.2 kg/l at 25 °C at 25 °C HSDB
In methanol 232, acetone 7.6, diethyl ether 0.2, benzene 0.07, carbon tetrachloride 0.04, heptane 0.02 (all in g/l, at 25 °C) at 25 °C HSDB

TCA-sodium (ISO) vapor pressure

Property Value Conditions Source
Vapor pressure 750.062 mmHg below this value, at 70 °C HSDB
3e-8 mmHg Haz-Map

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

TCA-sodium (ISO) storage and handling

TCA-sodium (ISO) safe storage

Separated from strong bases. Dry.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Planning storage for a mix of chemicals? Check TCA-sodium (ISO) in the storage compatibility matrix →

10 · Questions

TCA-sodium (ISO) — frequently asked questions

What is the CAS number of TCA-sodium (ISO)?

The CAS number of TCA-sodium (ISO) is 650-51-1. Its EC number is 211-479-2.

What is the chemical formula of TCA-sodium (ISO)?

The molecular formula of TCA-sodium (ISO) is C2Cl3NaO2 and its molecular weight is 185.36 g/mol.

What does a TCA-sodium (ISO) label have to show?

Under CLP Annex VI the label for TCA-sodium (ISO) carries the pictograms Exclamation mark and Environment and the signal word is Warning.

Is TCA-sodium (ISO) flammable?

CLP Annex VI assigns TCA-sodium (ISO) no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is TCA-sodium (ISO) a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for TCA-sodium (ISO). Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the melting point of TCA-sodium (ISO)?

The melting point reported for TCA-sodium (ISO) is 182.5 °C (360.5 °F), range, midpoint shown (HSDB).

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