Substance profile
Thiabendazole
Thiabendazole is colorless crystals and is odorless.
01 · Identification
What Thiabendazole is
Thiabendazole is colorless crystals and is odorless. Its molecular formula is C10H7N3S and its molecular weight is 201.25 g/mol. It melts at 305 °C, is slightly soluble in water.
Under the GHS it carries the signal word Warning.
02 · Identifiers
Thiabendazole identifiers and molecular data
Thiabendazole CAS number and EC number
Thiabendazole molecular formula and molecular weight
Other names for Thiabendazole
- thiabendazole (ISO)
- 2-(thiazol-4-yl)benzimidazole
03 · GHS classification
Thiabendazole hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Thiabendazole pictograms and signal word
Thiabendazole hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Thiabendazole hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Thiabendazole. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Thiabendazole
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Thiabendazole issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Thiabendazole precautionary statements
CLP Annex VI assigns 3 precautionary statements to Thiabendazole. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Thiabendazole name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | тиабендазол (ISO) 2-(тиазол-4-ил)бензимидазол |
| Spanish español | Tiabendazol (ISO) 2-(tiazol-4-il)-benzimidazol |
| Czech čeština | thiabendazol (ISO) 2-(thiazol-4-yl)benzimidazol |
| Danish dansk | thiabendazol (ISO) 2-(thiazol-4-yl)benzimidazol |
| German Deutsch | Thiabendazol (ISO) 2-(Thiazol-4-yl)benzimidazol |
| Estonian eesti | tiabendasool (ISO) 2-(tiasool-4-üül)bensimidasool |
| Greek ελληνικά | thiabendazole (θειαβενδαζόλη) (ISO) 2-(θειαζολ-4-υλο)βενζιμιδαζόλη |
| English English | thiabendazole (ISO) 2-(thiazol-4-yl)benzimidazole |
| French français | thiabendazole (ISO) 2-thiazol-4-yl-1H-benzoimidazole |
| Croatian hrvatski | tiabendazol (ISO) 2-(tiazol-4-il)benzimidazol |
| Italian italiano | tiabendazolo (ISO) 2-(tiazol-4-il)benzimidazolo |
| Latvian latviešu | tiabendazols (ISO) 2-(tiazol-4-il)benzimidazols |
| Lithuanian lietuvių | tiabendazolas (ISO) 2-(tiazol-4-il)benzimidazolas |
| Hungarian magyar | tiabendazol (ISO) 2-(tiazol-4-il)benzimidazol |
| Maltese Malti | tjabendażol (ISO) 2-(tijażol-4-il)benżimidażol |
| Dutch Nederlands | thiabendazool (ISO) 2-(thiazool-4-yl)benzimidazool |
| Polish polski | tiabendazol (ISO) 2-(tiazol-4-ilo)benzimidazol |
| Portuguese português | tiabendazole (ISO) 2-(tiazol-4-il)benzimidazole |
| Romanian română | tiabendazol (ISO) 2-(tiazol-4-il)benzimidazol |
| Slovak slovenčina | tiabendazol (ISO) 2-(tiazol-4-yl)benzimidazol |
| Slovenian slovenščina | tiabendazol (ISO) 2-(tiazol-4-il)benzimidazol |
| Finnish suomi | Tiabendatsoli (ISO) 2-(tiatsol-4-yyli)bentsimidatsoli |
| Swedish svenska | tiabendazol (ISO) 2-(tiazol-4-yl)bensimidazol |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Thiabendazole GHS label elements
Everything CLP Annex VI fixes for Thiabendazole, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
Thiabendazole
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Avoid release to the environment.
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Thiabendazole in the GHS label constructor →
07 · Health hazards
Thiabendazole health hazards and exposure limits
Thiabendazole hazard summary
Allergic contact dermatitis (ACD) reported in feed mill workers; [Kanerva, p. 1839] Ingestion of high doses can cause hepatic injury. [Zimmerman, p. 412] Reports of liver injury, CNS effects, and hypersensitivity reactions (rashes, conjunctivitis, erythema multiforme, Stevens-Johnson syndrome, and angioedema) in patients; Report of ACD in banana plantation employees; [HSDB] The hypophosphite salt (CAS# 28558-32-9) is used in the non-food applications; Not irritating to skin or eyes and not a skin sensitizer; May interfere with thyroid-pituitary homeostasis; Likely to be carcinogenic at doses high enough to cause disturbance of the thyroid hormone balance. It is not likely to be carcinogenic at doses lower than those which could cause a disturbance of this hormonal balance. [EPA REDs]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Thiabendazole carcinogenicity classification
Cancer Classification: Likely to be Carcinogenic to Humans at High Doses; Not Likely to be Carcinogenic to Humans at Low Doses
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
Thiabendazole properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Thiabendazole melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 304.5 °C (580.1 °F) | range, midpoint shown | HSDB |
| 304.44 °C (580 °F) | range, midpoint shown | CAMEO | |
| 300 °C (572 °F) | HMDB |
Thiabendazole density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.103 g/cm³ | at 25 °C, Thiabendazole hypophosphite | HSDB |
Thiabendazole solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Max solubility in water at pH 2.2: 3.84%; slightly sol in alcohols, esters, chlorinated hydrocarbons | HSDB | |
| Slightly soluble in ethanol | HSDB | ||
| In n-heptane <0.1, xylene 0.13, methanol 8.28, 1,2-dichloroethane 0.81, acetone 2.43, ethyl acetate 1.49, n-octanol 3.91, all in g/L at 25 °C | at 25 °C | HSDB |
Thiabendazole vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 4e-9 mmHg | at 25 °C | HSDB |
| Negligible (NTP, 1992) | CAMEO |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Thiabendazole storage and handling
Thiabendazole storage conditions
Thiabendazole tablets and oral suspension should be stored in tight containers at 15 - 30 °C. The oral suspension should be protected from freezing.
Source: Hazardous Substances Data Bank (HSDB)
Thiabendazole incompatible materials
Incompatible with a number of pesticides including copper-containing fungicides, & highly alkaline materials.
Source: Hazardous Substances Data Bank (HSDB)
Thiabendazole reactivity
THIABENDAZOLE is incompatible with a number of pesticides, including copper-containing fungicides, and with highly alkaline materials. It is a chelating agent, binding many metals including iron, but not calcium (NTP, 1992)
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Thiabendazole in the storage compatibility matrix →
10 · Questions
Thiabendazole — frequently asked questions
What is the CAS number of Thiabendazole?
The CAS number of Thiabendazole is 148-79-8. Its EC number is 205-725-8.
What is the chemical formula of Thiabendazole?
The molecular formula of Thiabendazole is C10H7N3S and its molecular weight is 201.25 g/mol.
What does a Thiabendazole label have to show?
Under CLP Annex VI the label for Thiabendazole carries the pictogram Environment and the signal word is Warning.
Is Thiabendazole flammable?
CLP Annex VI assigns Thiabendazole no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Thiabendazole a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Thiabendazole. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the melting point of Thiabendazole?
The melting point reported for Thiabendazole is 304.5 °C (580.1 °F), range, midpoint shown (HSDB).
How should Thiabendazole be stored?
Thiabendazole tablets and oral suspension should be stored in tight containers at 15 - 30 °C. The oral suspension should be protected from freezing. (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Thiabendazole
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