Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Trifluralin (ISO) (containing < 0.5 ppm NPDA)

Trifluralin (ISO) (containing < 0.5 ppm NPDA) is yellow crystals with a no appreciable odor.

CAS 1582-09-8 C13H16F3N3O4 335.28 g/mol Warning

01 · Identification

What Trifluralin (ISO) (containing… is

Trifluralin (ISO) (containing < 0.5 ppm NPDA) is yellow crystals with a no appreciable odor. Its molecular formula is C13H16F3N3O4 and its molecular weight is 335.28 g/mol. It melts at 42 °C, is slightly soluble in water.

Under the GHS it carries the signal word Warning. It is classed as hazardous Air Pollutants (HAPs).

02 · Identifiers

Trifluralin (ISO) (containing… identifiers and molecular data

Trifluralin (ISO) (containing… CAS number and EC number

CAS number1582-09-8
EC number216-428-8
Index number (CLP Annex VI)609-046-00-1

Trifluralin (ISO) (containing… molecular formula and molecular weight

Molecular formulaC13H16F3N3O4
Molecular weight335.28 g/mol
Chemical class Hazardous Air Pollutants (HAPs)

Other names for Trifluralin (ISO) (containing…

  • α,α,α-trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine (containing < 0.5 ppm NPDA)
  • 2,6-dinitro-N,N-dipropyl-4-trifluoromethylaniline (containing < 0.5 ppm NPDA)
  • N,N-dipropyl-2,6-dinitro-4-trifluoromethylaniline (containing < 0.5 ppm NPDA)

03 · GHS classification

Trifluralin (ISO) (containing… hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Trifluralin (ISO) (containing… pictograms and signal word

Signal wordWarning

Trifluralin (ISO) (containing… hazard class and category

GHS hazard classes Trifluralin (ISO)… falls into
Hazard class Category From code Pictogram
Skin sensitisation GHS chapter 3.4 Category 1 or 1A or 1B H317 GHS07
Carcinogenicity GHS chapter 3.6 Category 2 H351 GHS08
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

Trifluralin (ISO) (containing… hazard statements (H-codes)

Hazard statements assigned to Trifluralin (ISO)…
CodeHazard statement
H351 Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H317 May cause an allergic skin reaction.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Trifluralin (ISO)…. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Trifluralin (ISO)…

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Trifluralin (ISO)… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Trifluralin (ISO) (containing… precautionary statements

CLP Annex VI assigns 10 precautionary statements to Trifluralin (ISO)…. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Trifluralin (ISO) (containing… name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български трифлуралин (ISO) (съдържащ < 0,5 ppm NPDA) 2,6-динитро- N , N -дипропил-α, α,α-трифлуоро- p -толуидин (съдържащ < 0,5 ppm NPDA)2,6-динитро- N , N -дипропил-4-трифлуорометиланилин (съдържащ <0,5 ppm NPDA)N , N -дипропил-2,6-динитро-4-трифлуорометиланилин (съдържащ < 0,5 ppm NPDA)
Spanish español Trifluralina (ISO) (con < 0,5 ppm de NPDA) α, α, α-trifluoro-2,6-dinitro- N, N -dipropil- p -toluidina (con < 0,5 ppm de NPDA)2,6-dinitro- N, N -dipropil-4-trifluorometilanilina (con < 0,5 ppm de NPDA)N, N -dipropil-2,6-dinitro-4-trifluorometilanilina (con < 0,5 ppm de NPDA)
Czech čeština trifluralin (ISO) (obsahující < 0,5 ppm NPDA) 2,6-dinitro- N, N -dipropyl-4-(trifluormethyl)anilin (obsahující < 0,5 ppm NPDA)
Danish dansk trifluralin (ISO) (indeholdende < 0,5 ppm NPDA) α, α,α-trifluor-2,6-dinitro- N, N- dipropyl- p -toluidin (indeholdende < 0,5 ppm NPDA)2,6-dinitro- N, N- dipropyl-4-trifluormethylanilin (indeholdende < 0,5 ppm NPDA)N, N- dipropyl-2,6-dinitro-4-trifluormethylanilin (indeholdende < 0,5 ppm NPDA)
German Deutsch Trifluralin (ISO) (enthält <0,5 ppm NPDA) α, α, α-Trifluor-2,6-dinitro- N, N - dipropyl- p -toluidin (enthält < 0,5 ppm NPDA)2,6-Dinitro- N, N -dipropyl-4-trifluormethylanilin (enthält < 0,5 ppm NPDA)N, N -Dipropyl-2,6-dinitro-4-trifluormethylanilin (enthält < 0,5 ppm NPDA)
Estonian eesti trifluraliin (ISO) (NPDA sisaldus < 0,5 ppm) α, α,α-trifluoro-2,6-dinitro- N , N -dipropüül- p -toluidiin (NPDA sisaldus < 0,5 ppm)2,6-dinitro- N , N -dipropüül-4-trifluorometüülaniliin (NDPA sisaldus < 0,5 ppm)N , N -dipropüül-2,6-dinitro-4-trifluorometüülaniliin (NDPA sisaldus < 0,5 ppm)
Greek ελληνικά trifluralin (τριφθοραλίνη) (ISO) (περιέχει < 0,5 ppm NPDA) α, α,α-τριφθορο-2,6-δινιτρο- N, N -διπροπυλο- p -τολουιδίνη (περιέχει < 0,5 ppm NPDA)2,6-δινιτρο- N, N -διπροπυλο-4-τριφθορομεθυλανιλίνη (περιέχει < 0,5 ppm NPDA)N, N -διπροπυλο-2,6-δινιτρο-4-τριφθορομεθυλανιλίνη (περιέχει < 0,5 ppm NPDA)
English English trifluralin (ISO) (containing <0.5 ppm NPDA) α, α, α-trifluoro-2,6-dinitro- N, N -dipropyl- p -toluidine (containing < 0,5 ppm NPDA)2,6-dinitro- N, N -dipropyl-4-trifluoromethylaniline (containing < 0,5 ppm NPDA)N, N -dipropyl-2,6-dinitro-4-trifluoromethylaniline (containing < 0.5 ppm NPDA)
French français trifluraline (ISO) (contenant < 0,5 ppm de NPDA) α, α, α-trifluoro-2,6-dinitro- N, N -dipropyl- p -toluidine (contenant < 0,5 ppm de NPDA)2,6-dinitro- N, N -dipropyl-4-trifluorométhylaniline (contenant < 0,5 ppm de NPDA)N, N -dipropyl-2,6-dinitro-4-trifluorométhylaniline (contenant < 0,5 ppm de NPDA)
Croatian hrvatski trifluralin (ISO) (sadržava < 0,5 ppm NPDA-a) α, α,α -trifluor-2,6-dinitro- N, N -dipropil- p -toluidin (sadržava < 0,5 ppm NPDA-a)2,6-dinitro- N, N -dipropil-4-trifluormetilanilin (sadržava < 0,5 ppm NPDA-a)N, N -dipropil-2,6-dinitro-4-trifluormetilanilin (sadržava < 0,5 ppm NPDA-a)
Italian italiano trifluralin (ISO) (contenente < 0,5 ppm NPDA) alfa, alfa, alfa-trifluoro-2,6-dinitro- N , N -dipropil-p-toluidina (contenente < 0,5 ppm NPDA)2,6-dinitro- N , N -dipropil-4-(trifluorometil)anilina (contenente < 0,5 ppm NPDA)N , N -dipropil-2,6-dinitro-4-(trifluorometil)anilina (contenente < 0,5 ppm NPDA)
Latvian latviešu trifluralīns (ISO) (satur < 0,5 ppm NPDA) α, α,α-trifluor-2,6-dinitro- N, N - dipropil- p -toluidīns (satur < 0,5 ppm NPDA)2,6-dinitro- N, N -dipropil-4-trifluormetilanilīns (satur < 0,5 ppm NPDA)N, N -dipropil-2,6-dinitro-4-trifluormetilanilīns (satur < 0,5 ppm NPDA)
Lithuanian lietuvių trifluralinas (ISO) (turintis < 0,5 ppm NPDA) α, α,α-trifluor-2,6-dinitro- N, N -dipropil- p -toluidinas (turintis < 0,5 ppm NPDA)2,6-dinitro- N, N -dipropil-4-trifluormetilanilinas (turintis < 0,5 ppm NPDA)N, N -dipropil-2,6-dinitro-4-trifluormetilanilinas (turintis < 0,5 ppm NPDA)
Hungarian magyar trifluralin (ISO) (<0,5 ppm NPDA tartalommal) α, α,α-trifluor-2,6-dinitro- N, N -dipropil-p-toluidin (<0,5 ppm NPDA tartalommal)2,6-dinitro- N, N -dipropil-4-trifluormetilanilin (<0,5 ppm NPDA tartalommal)N, N -dipropil-2,6-dinitro-4-trifluormetilanilin (<0,5 ppm NPDA tartalommal)
Maltese Malti trifluralin (ISO) (li fih <0.5 ppm NPDA) α, α, α-trifluworo-2,6-dinitro- N, N -dipropil- p -toluidine (li fih < 0,5 ppm NPDA)2,6-dinitro- N, N -dipropil-4-trifluworometilanilina (li fih < 0,5 ppm NPDA)N, N -dipropil-2,6-dinitro-4-trifluworometilanilina (li fih < 0.5 ppm NPDA)
Dutch Nederlands trifluralin (ISO) (met < 0,5 ppm NPDA) α, α,α-trifluor-2,6-dinitro- N , N -dipropyl- p -toluïdine (met < 0,5 ppm NPDA)2,6-dinitro- N , N -dipropyl-4-trifluormethylaniline (met < 0,5 ppm NPDA)N , N -dipropyl-2,6-dinitro-4-trifluormethylaniline (met < 0,5 ppm NPDA)
Polish polski trifluralina (ISO) (zawierająca < 0,5 ppm NPDA)α, α,α-trifluoro-2,6-dinitro- N, N -dipropylo- p -toluidyna (zawierająca < 0,5 ppm NPDA)2,6-dinitro- N, N -dipropylo-4-(trifluorometylo)anilina (zawierająca < 0,5 ppm NPDA)N, N -dipropylo-2,6-dinitro-4-trifluorometyloanilina (zawierająca < 0,5 ppm NPDA)
Portuguese português trifluralina (ISO) (<0,5 ppm de NPDA) α, α,α-trifluoro-2,6-dinitro- N , N -dipropil- p -toluidina (<0,5 ppm de NPDA)2,6-dinitro- N , N -dipropil-4-trifluorometilanilina (< 0,5 ppm de NPDA)N , N -dipropil-2,6-dinitro-4-trifluorometilanilina (< 0,5 ppm de NPDA)
Romanian română trifluralin (ISO) (cu conținut mai mic de 0,5 ppm NPDA) α, α, α-trifluoro-2,6-dinitro- N, N -dipropil- p -toluidină (cu conținut mai mic de 0,5 ppm NPDA)2,6-dinitro- N, N -dipropil-4-trifluorometilanilina (cu conținut mai mic de 0,5 ppm NPDA)N, N -dipropil-2,6-dinitro-4-trifluorometilanilina (cu conținut mai mic de 0,5 ppm NPDA)
Slovak slovenčina trifluralín (ISO) (s obsahom < 0,5 ppm NPDA) α, α,α-trifluór-2,6-dinitro- N, N -dipropyl- para -toluidín (s obsahom < 0,5 ppm NPDA)2,6-dinitro- N, N -dipropyl-4-(trifluórmetyl)anilín (s obsahom < 0,5 ppm NPDA)N, N -dipropyl-2,6-dinitro-4-(trifluórmetyl)anilín (s obsahom < 0,5 ppm NPDA)
Slovenian slovenščina trifluralin (ISO) (vsebuje < 0,5 ppm NPDA) α, α,α-trifluoro-2,6-dinitro- N, N -dipropil- p -toluidin (vsebuje < 0,5 ppm NPDA)2,6-dinitro- N, N -dipropil-4-trifluorometilanilin (vsebuje < 0,5 ppm NPDA)N, N -dipropil-2,6-dinitro-4-trifluorometilanilin (vsebuje < 0,5 ppm NPDA)
Finnish suomi trifluraliini (ISO), joka sisältää < 0,5 ppm NPDA:ta α, α,α-trifluori-2,6-dinitro- N, N -dipropyyli- p -toluidiini, joka sisältää < 0,5 ppm NPDA:ta2,6-dinitro- N, N -dipropyyli-4-trifluorimetyylianiliini, joka sisältää < 0,5 ppm NPDA:taN, N -dipropyyli-2,6-dinitro-4-trifluorimetyylianiliini, joka sisältää < 0,5 ppm NPDA:ta
Swedish svenska trifluralin (ISO) (innehållande < 0,5 ppm NPDA) α, α, α-trifluor-2,6-dinitro- N, N -dipropyl- p -toluidin (innehållande < 0,5 ppm NPDA)2,6-dinitro- N, N -dipropyl-4-trifluormetylanilin (innehållande < 0,5 ppm NPDA)N, N -dipropyl-2,6-dinitro-4-trifluormetylanilin (innehållande < 0,5 ppm NPDA)

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Trifluralin (ISO) (containing… GHS label elements

Everything CLP Annex VI fixes for Trifluralin (ISO)…, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS08 Health hazard pictogramGHS07 Exclamation mark pictogramGHS09 Environment pictogram

Warning

Trifluralin (ISO) (containing…

  • Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • May cause an allergic skin reaction.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Obtain special instructions before use.
  • Avoid breathing dust/fume/gas/mist/vapours/spray.
  • Contaminated work clothing should not be allowed out of the workplace.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF exposed or concerned:
  • Get medical advice/attention.
  • If skin irritation or rash occurs:
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Trifluralin (ISO)… in the GHS label constructor →

07 · Health hazards

Trifluralin (ISO) (containing… health hazards and exposure limits

Trifluralin (ISO) (containing… hazard summary

Trifluralin is used as a herbicide. No information is available on the acute (short-term), chronic (long- term), reproductive, developmental, or carcinogenic effects of trifluralin in humans. Decreased weight gain and effects on the blood and liver were observed in dogs chronically exposed to trifluralin in their diet. Skeletal abnormalities and depressed fetal weight were observed in the offspring of rodents exposed via gavage (experimentally placing the chemical in the stomach). Increased incidences of urinary tract tumors and thyroid tumors were observed in rats exposed to trifluralin in their diet. Trifluralin did not produce statistically significant increases in tumors in other studies. EPA has classified trifluralin as a Group C, possible human carcinogen (cancer-causing agent).

Source: EPA Hazardous Air Pollutants

Trifluralin (ISO) (containing… carcinogenicity classification

IARC classification Group 3 — Not classifiable as to its carcinogenicity to humans
IARC monographs Volume 53: (1991) Occupational Exposures in Insecticide Application, and Some Pesticides

Studied by the US National Toxicology Program: TR-034: Bioassay of Trifluralin for Possible Carcinogenicity (CASRN 1582-09-8) (1978 )

Evaluation: There is inadequate evidence in humans for the carcinogenicity of trifluralin. There is limited evidence in experimental animals for the carcinogenicity of technical grade trifluralin. Overall evaluation: Trifluralin is not classifiable as to its carcinogenicity to humans (Group 3).

Source: Hazardous Substances Data Bank (HSDB)

Cancer Classification: Group C Possible Human Carcinogen

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

08 · Physical and chemical properties

Trifluralin (ISO) (containing… properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Trifluralin (ISO) (containing… boiling point

Property Value Conditions Source
Boiling point 139.5 °C (283.1 °F) range, midpoint shown, at 4.2 mmHg (reduced pressure) HSDB
139.5 °C (283.1 °F) range, midpoint shown, at 3.75031 mmHg (reduced pressure) ICSC
Decomposes (NTP, 1992) decomposes CAMEO

Trifluralin (ISO) (containing… melting point

Property Value Conditions Source
Melting point 42 °C (107.6 °F) HSDB
49 °C (120.2 °F) ICSC

Trifluralin (ISO) (containing… density

Property Value Conditions Source
Density 1.36 g/cm³ at 22 °C HSDB
1.294 g/cm³ at 25 °C CAMEO

Trifluralin (ISO) (containing… solubility

Property Value Conditions Source
Solubility Slightly soluble in water (0.0024 g/100 mL) HSDB
In acetone, chloroform, acetonitrile, toluene, ethyl acetate >1000, methanol 33-40, hexane 50-67, all in g/L at 25 °C at 25 °C HSDB
Solubility at 25 °C: 82 g/100 mL dimethylformamide; 83 g/100 mL dioxane; 44 g/100 mL methyl cellosolve; 88 g/100 mL methyl ethyl ketone at 25 °C HSDB

Trifluralin (ISO) (containing… vapor pressure

Property Value Conditions Source
Vapor pressure 0.0000458 mmHg at 25 °C HSDB
0.00007501 mmHg at 25 °C ICSC
0.000199 mmHg at 29.5 °C CAMEO

Trifluralin (ISO) (containing… flash point

Property Value Conditions Source
Flash point 151 °C (303.8 °F) closed cup HSDB
100 °C (212 °F) ICSC
85 °C (185 °F) above this value CAMEO

Trifluralin (ISO) (containing… corrosivity

Property Value Conditions Source
Corrosivity Technical not corrosive HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Trifluralin (ISO)… fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Trifluralin (ISO) (containing… fire potential

This chemical is a combustible solid. ...

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

Trifluralin (ISO) (containing… storage and handling

Trifluralin (ISO) (containing… safe storage

Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Store only in original packaging. Store in an area without drain or sewer access.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Trifluralin (ISO) (containing… storage conditions

Do not store near heat or open flame. /Gowan Trifluralin 10G/

Source: Hazardous Substances Data Bank (HSDB)

Trifluralin (ISO) (containing… incompatible materials

Store in temperatures above 4.4 °C. Fluorocarbons can react violently with barium, potassium, sodium.

Source: Hazardous Substances Data Bank (HSDB)

Trifluralin (ISO) (containing… reactivity

TRIFLURALIN is a trifluoromethyl dinitroaniline derivative. Dinitroaniline has a record of industrial explosions. Nothing has been reported implicating trifluralin in any such accidents. This may be because of the trifluoromethyl substitution may mitigate the instability of the molecule. However, care should be taken in the extremes of heat, shock, and friction sources that may trigger an explosive release of energy.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Trifluralin (ISO)… in the storage compatibility matrix →

11 · Questions

Trifluralin (ISO) (containing… — frequently asked questions

What is the CAS number of Trifluralin (ISO) (containing…?

The CAS number of Trifluralin (ISO) (containing… is 1582-09-8. Its EC number is 216-428-8.

What is the chemical formula of Trifluralin (ISO) (containing…?

The molecular formula of Trifluralin (ISO) (containing… is C13H16F3N3O4 and its molecular weight is 335.28 g/mol.

What does a Trifluralin (ISO) (containing… label have to show?

Under CLP Annex VI the label for Trifluralin (ISO) (containing… carries the pictograms Health hazard, Exclamation mark and Environment and the signal word is Warning.

Is Trifluralin (ISO) (containing… flammable?

CLP Annex VI assigns Trifluralin (ISO) (containing… no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 151 °C (303.8 °F), closed cup (HSDB).

Is Trifluralin (ISO) (containing… a carcinogen?

CLP Annex VI assigns Trifluralin (ISO) (containing… H351 — suspected of causing cancer. That is category 2: the evidence points that way but is not conclusive. IARC places it in Group 3: not classifiable as to its carcinogenicity to humans.

What is the boiling point of Trifluralin (ISO) (containing…?

The boiling point reported for Trifluralin (ISO) (containing… is 139.5 °C (283.1 °F), range, midpoint shown, at 4.2 mmHg (reduced pressure) (HSDB).

What is the melting point of Trifluralin (ISO) (containing…?

The melting point reported for Trifluralin (ISO) (containing… is 42 °C (107.6 °F) (HSDB).

How should Trifluralin (ISO) (containing… be stored?

Do not store near heat or open flame. /Gowan Trifluralin 10G/ (Hazardous Substances Data Bank (HSDB))

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