Substance profile
1-Bromopropane
1-Bromopropane is a colorless liquid with a sweet odor.
01 · Identification
What 1-Bromopropane is
1-Bromopropane is a colorless liquid with a sweet odor. Its molecular formula is C3H7Br and its molecular weight is 122.99 g/mol. It boils at 71 °C, melts at -110 °C.
Under the GHS it carries the signal word Danger. It is classed as flammable agents - 3rd degree.
02 · Identifiers
1-Bromopropane identifiers and molecular data
1-Bromopropane CAS number and EC number
1-Bromopropane molecular formula and molecular weight
Other names for 1-Bromopropane
- n-propyl bromide
03 · GHS classification
1-Bromopropane hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
1-Bromopropane pictograms and signal word
1-Bromopropane hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Flammable liquids GHS chapter 2.6 | Category 2 | H225 | GHS02 |
| Skin corrosion/irritation GHS chapter 3.2 | Category 2 | H315 | GHS07 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 2A | H319 | GHS07 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 3 | H335 | GHS07 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 3 narcotic | H336 | GHS07 |
| Specific target organ toxicity - repeated exposure GHS chapter 3.9 | Category 2 | H373 | GHS08 |
1-Bromopropane hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H225 | Highly flammable liquid and vapour. |
| H360FD | May damage fertility. May damage the unborn child. |
| H335 | May cause respiratory irritation. |
| H336 | May cause drowsiness or dizziness. |
| H373 | May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H315 | Causes skin irritation. |
| H319 | Causes serious eye irritation. |
This page lists only the codes assigned to 1-Bromopropane. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 1-Bromopropane
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 1-Bromopropane issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
1-Bromopropane precautionary statements
CLP Annex VI assigns 17 precautionary statements to 1-Bromopropane. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
1-Bromopropane name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 1-бромопропан n -пропилбромид |
| Spanish español | 1-Bromopropano bromuro de n -propilo |
| Czech čeština | 1-brompropan propylbromid |
| Danish dansk | 1-brompropan: n-propylbromid |
| German Deutsch | 1-Brompropan n-Propylbromid |
| Estonian eesti | 1-bromopropaan n -propüülbromiid |
| Greek ελληνικά | 1-βρωμοπροπάνιο n-προπυλοβρωμίδιo |
| English English | 1-bromopropane n-propyl bromide |
| French français | 1-bromopropane bromure de n-propyle |
| Croatian hrvatski | 1-brompropan n -propil-bromid |
| Italian italiano | 1-bromopropano bromuro di propile |
| Latvian latviešu | 1-brompropāns n-propilbromīds |
| Lithuanian lietuvių | 1-brompropanas n-propilbromidas |
| Hungarian magyar | 1-brómpropán n-propil-bromid |
| Maltese Malti | 1-bromopropan n-bromur tal-propil |
| Dutch Nederlands | 1-broompropaan n -propylbromide |
| Polish polski | 1-bromopropan bromek propylu |
| Portuguese português | 1-bromopropano brometo de n -propilo |
| Romanian română | 1-bromopropan bromură de n-propil |
| Slovak slovenčina | 1-brómpropán propylbromid |
| Slovenian slovenščina | 1-bromopropan n-propil bromid |
| Finnish suomi | 1-bromipropaani n-propyylibromidi |
| Swedish svenska | 1-brompropan n-propylbromid |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
1-Bromopropane GHS label elements
Everything CLP Annex VI fixes for 1-Bromopropane, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
1-Bromopropane
- Highly flammable liquid and vapour.
- May damage fertility. May damage the unborn child.
- May cause respiratory irritation.
- May cause drowsiness or dizziness.
- May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Causes skin irritation.
- Causes serious eye irritation.
- Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- Keep container tightly closed.
- Use explosion-proof [electrical/ventilating/lighting/…] equipment.
- Use only non-sparking tools.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Wash … thoroughly after handling.
- Do not eat, drink or smoke when using this product.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF ON SKIN:
- IF IN EYES:
- Get medical advice/attention.
- Get medical advice/attention if you feel unwell.
- If skin irritation occurs:
- If eye irritation persists:
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Wash with plenty of water/…
- Store in a well-ventilated place.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 1-Bromopropane in the GHS label constructor →
07 · Health hazards
1-Bromopropane health hazards and exposure limits
1-Bromopropane hazard summary
1-Bromopropane is a colorless liquid. Commercial 1-bromopropane includes not only 1-bromopropane, but also additives that improve its performance in the desired application and stabilizers to inhibit decomposition. 1-Bromopropane was originally used in the production of pesticides, flavors and fragrances, pharmaceuticals, and other chemicals.
Source: Agency for Toxic Substances and Disease Registry (ATSDR)
1-Bromopropane carcinogenicity classification
Under the conditions of these 2-year inhalation studies, there was some evidence of carcinogenic activity of 1-bromopropane in male F344/N rats based on the occurrence of rare adenomas of the large intestine and increased incidences of epithelial neoplasms of the skin (keratoacanthoma, squamous cell carcinoma, and basal cell neoplasms). Increased incidences of malignant mesothelioma and pancreatic islet adenoma may also have been related to 1-bromopropane exposure. There was clear evidence of carcinogenic activity of 1-bromopropane in female F344/N rats based on increased incidences of adenoma of the large intestine. Increased incidences of neoplasms of the skin may also have been related to 1-bromopropane exposure. There was no evidence of carcinogenic activity of 1-bromopropane in male B6C3F1 mice exposed to concentrations of 62.5, 125, or 250 ppm 1-bromopropane. There was clear evidence of carcinogenic activityof 1-bromopropane in female B6C3F1 mice based on increased incidences of alveolar/bronchiolar neoplasms.
Source: US National Toxicology Program · TR-564: Toxicology and Carcinogenesis Studies of 1-Bromopropane (CASRN 106-94-5) in F344/N Rats and B6C3F1 (Inhalation Studies) (2011 )
1-Bromopropane is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Source: Hazardous Substances Data Bank (HSDB)
Evaluation: There is inadequate evidence in humans for the carcinogenicity of 1-bromopropane. There is sufficient evidence in experimental animals for the carcinogenicity of 1-bromopropane. Overall evaluation: 1-Bromopropane is possibly carcinogenic to humans (Group 2B).
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
1-Bromopropane properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
1-Bromopropane boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 71 °C (159.8 °F) | HSDB | |
| 71.11 °C (160 °F) | at 760 mmHg | CAMEO |
1-Bromopropane melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -110 °C (-166 °F) | HSDB |
1-Bromopropane density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.35 g/cm³ | ICSC | |
| 1.353 g/cm³ | at 20 °C | HSDB | |
| 1.3537 g/cm³ | at 20 °C | CAMEO |
1-Bromopropane solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Slightly soluble in water | HSDB | |
| Soluble in acetone, ethanol, ether, benzene chloroform, carbon tetrachloride | HSDB | ||
| In water, 2,450 mg/L at 20 °C | at 20 °C | HSDB |
1-Bromopropane vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 274.01 mmHg | CAMEO | |
| 110.8 mmHg | at 20 °C | HSDB | |
| 99.7582 mmHg | at 18 °C | ICSC |
1-Bromopropane flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 22 °C (71.6 °F) | HSDB | |
| 25.56 °C (78 °F) | CAMEO |
1-Bromopropane autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 490 °C (914 °F) | HSDB |
1-Bromopropane lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | 4.6 % by volume | CAMEO | |
| 3.4 % by volume | ICSC |
1-Bromopropane upper explosive limit (UEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Upper explosive limit (UEL) | 9.1 % by volume | ICSC |
1-Bromopropane vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 4.25 (air = 1) | HSDB | |
| 4.3 (air = 1) | ICSC |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
1-Bromopropane fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
1-Bromopropane fire potential
Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
1-Bromopropane storage and handling
1-Bromopropane safe storage
Fireproof. Well closed. Separated from strong oxidants and strong bases. Store in an area without drain or sewer access. Ventilation along the floor.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
1-Bromopropane storage conditions
PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/
Source: Hazardous Substances Data Bank (HSDB)
1-Bromopropane incompatible materials
Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. /Halogenated aliphatic compounds/
Source: Hazardous Substances Data Bank (HSDB)
1-Bromopropane reactivity
Halogenated aliphatic compounds, such as 1-BROMOPROPANE, are moderately or very reactive. Halogenated organics generally become less reactive as more of their hydrogen atoms are replaced with halogen atoms. Low molecular weight haloalkanes are highly flammable and can react with some metals to form dangerous products. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. Emits toxic fumes of bromine when burned.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 1-Bromopropane in the storage compatibility matrix →
11 · Questions
1-Bromopropane — frequently asked questions
What is the CAS number of 1-Bromopropane?
The CAS number of 1-Bromopropane is 106-94-5. Its EC number is 203-445-0.
What is the chemical formula of 1-Bromopropane?
The molecular formula of 1-Bromopropane is C3H7Br and its molecular weight is 122.99 g/mol.
What does a 1-Bromopropane label have to show?
Under CLP Annex VI the label for 1-Bromopropane carries the pictograms Flame, Health hazard and Exclamation mark and the signal word is Danger.
Is 1-Bromopropane flammable?
Yes. CLP Annex VI assigns 1-Bromopropane H225 — highly flammable liquid and vapour. The flash point reported for it is 22 °C (71.6 °F) (HSDB).
Is 1-Bromopropane a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for 1-Bromopropane. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health. IARC places it in Group 2B: possibly carcinogenic to humans.
What is the boiling point of 1-Bromopropane?
The boiling point reported for 1-Bromopropane is 71 °C (159.8 °F) (HSDB).
What is the melting point of 1-Bromopropane?
The melting point reported for 1-Bromopropane is -110 °C (-166 °F) (HSDB).
How should 1-Bromopropane be stored?
CLP Annex VI assigns 1-Bromopropane the storage statement P403. PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/ (Hazardous Substances Data Bank (HSDB))
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