Substance profile
Chlorothalonil
Chlorothalonil is colorless crystals and is odorless.
01 · Identification
What Chlorothalonil is
Chlorothalonil is colorless crystals and is odorless. Its molecular formula is C8Cl4N2 and its molecular weight is 265.9 g/mol. It boils at 350 °C, melts at 252 °C.
Under the GHS it carries the signal word Danger. It is classed as carcinogens.
02 · Identifiers
Chlorothalonil identifiers and molecular data
Chlorothalonil CAS number and EC number
Chlorothalonil molecular formula and molecular weight
Other names for Chlorothalonil
- chlorothalonil (ISO)
- tetrachloroisophthalonitrile
03 · GHS classification
Chlorothalonil hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Chlorothalonil pictograms and signal word
Chlorothalonil hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - inhalation GHS chapter 3.1 | Category 1 or 2 | H330 | GHS06 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 1 | H318 | GHS05 |
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
| Carcinogenicity GHS chapter 3.6 | Category 2 | H351 | GHS08 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 3 | H335 | GHS07 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Chlorothalonil hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H351 | Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H330 | Fatal if inhaled. |
| H335 | May cause respiratory irritation. |
| H318 | Causes serious eye damage. |
| H317 | May cause an allergic skin reaction. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Chlorothalonil. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Chlorothalonil
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Chlorothalonil issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Chlorothalonil precautionary statements
CLP Annex VI assigns 16 precautionary statements to Chlorothalonil. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Chlorothalonil name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | хлороталонил (ISO) тетрахлороизофталонитрил |
| Spanish español | Clorotalonilo (ISO) tetracloroisoftalonitrilo |
| Czech čeština | chlorthalonil (ISO) tetrachlorisoftalonitril2,4,5,6-tetrachlorbenzen-1,3-dikarbonitril |
| Danish dansk | chlorothalonil (ISO) tetrachlorisophthalonitril |
| German Deutsch | Chlorthalonil (ISO) Tetrachlorisophthalonitril |
| Estonian eesti | klorotaloniil (ISO) tetrakloroisoftalonitriil |
| Greek ελληνικά | chlorothalonil (χλωροθαλονίλη) (ISO) τετραχλωροϊσοφθαλονιτρίλιο |
| English English | chlorothalonil (ISO) tetrachloroisophthalonitrile |
| French français | chlorothalonil (ISO) tétrachloroisophtalonitrile |
| Croatian hrvatski | klorotalonil (ISO) tetraklorizoftalonitril |
| Italian italiano | clorotalonil (ISO) tetracloroisoftalonitrile |
| Latvian latviešu | hlortalonils (ISO) tetrahlorizoftalnitrils |
| Lithuanian lietuvių | chlortalonilas (ISO) tetrachlorizoftalonitrilas |
| Hungarian magyar | klórtalonil (ISO) tetraklórizoftalonitril |
| Maltese Malti | klorotalonil (ISO) tetrakloroisoftalonitril |
| Dutch Nederlands | chloorthalonil (ISO) tetrachloorisoftalonitril |
| Polish polski | chlorotalonil (ISO) tetrachloroizoftalonitryl |
| Portuguese português | clorotalonil (ISO) tetracloroisoftalonitrilo |
| Romanian română | clortalonil (ISO) tetracloroizoftalonitril |
| Slovak slovenčina | chlorotalonil (ISO) tetrachlórizoftalonitril |
| Slovenian slovenščina | klorotalonil (ISO) tetrakloroizoftalonitril |
| Finnish suomi | klorotaloniili (ISO) tetrakloori-isoftaalinitriili |
| Swedish svenska | klortalonil (ISO) tetraklorisoftalonitril |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Chlorothalonil GHS label elements
Everything CLP Annex VI fixes for Chlorothalonil, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Chlorothalonil
- Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Fatal if inhaled.
- May cause respiratory irritation.
- Causes serious eye damage.
- May cause an allergic skin reaction.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Obtain special instructions before use.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Use only outdoors or in a well-ventilated area.
- Contaminated work clothing should not be allowed out of the workplace.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF INHALED:
- IF IN EYES:
- IF exposed or concerned:
- Immediately call a POISON CENTER/doctor/…
- Get medical advice/attention.
- If skin irritation or rash occurs:
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Chlorothalonil in the GHS label constructor →
07 · Health hazards
Chlorothalonil health hazards and exposure limits
Chlorothalonil hazard summary
No cases of systemic poisoning have been documented, but allergic contact dermatitis has been reported. [EPA Pesticides] Occupational asthma reported in farmer; [Malo] It is a strong skin irritant; Allergic contact dermatitis reported in flower and vegetable growers and carpenters; [Kanerva, p. 786] Chlorothalonil can cause immunologic, occupational contact urticaria. [Kanerva, p. 219] A severe eye, mild skin, and respiratory tract irritant; May cause skin sensitization; [ICSC] Reports of contact dermatitis in agricultural workers, cabinet makers, and employees of a chlorothalonil manufacturing facility; Occupational asthma also reported; Workers in a packaging plant reported intense pain on ocular exposure; Moderate conjunctivitis and corneal irritation (no corneal opacity) were observed; [HSDB] A mild skin irritant; Can cause permanent eye injury; A weak skin sensitizer; [Syngenta MSDS]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Chlorothalonil carcinogenicity classification
Studied by the US National Toxicology Program: TR-041: Bioassay of Chlorothalonil for Possible Carcinogenicity (CASRN 1897-45-6) (1978 )
Cancer Classification: Group B2 Probable Human Carcinogen
Source: Hazardous Substances Data Bank (HSDB)
There is inadequate evidence for the carcinogenicity of chlorothalonil in humans. There is sufficient evidence in experimental animals for the carcinogenicity of chloroanothil. Overall evaluation: Chlorothalonil is possibly carcinogenic to humans (Group 2B).
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
Chlorothalonil properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Chlorothalonil boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 350 °C (662 °F) | HSDB | |
| 350 °C (662 °F) | at 760 mmHg | CAMEO |
Chlorothalonil melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 252.1 °C (485.8 °F) | HSDB | |
| 250.56 °C (483 °F) | range, midpoint shown | CAMEO | |
| 250.5 °C (482.9 °F) | range, midpoint shown | ICSC |
Chlorothalonil density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.8 g/cm³ | ICSC | |
| 1.732 g/cm³ | at 20 °C | HSDB | |
| 1.7 g/cm³ | at 25 °C | CAMEO |
Chlorothalonil solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Soluble in benzene | HSDB | |
| In water, 0.81 mg/L at 25 °C | at 25 °C | HSDB | |
| Solubility (g/L, 25 °C): 20.9 acetone; 22.4 1,2-dichloroethane; 13.8 ethyl acetate; 0.2 n-heptane; 1.7 methanol; 74.4 xylene | at 25 °C | HSDB |
Chlorothalonil vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 5.7e-7 mmHg | at 25 °C | HSDB |
| 0.01 mmHg | below this value, at 40 °C | CAMEO |
Chlorothalonil corrosivity
| Property | Value | Conditions | Source |
|---|---|---|---|
| Corrosivity | Non-corrosive | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
Chlorothalonil fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Chlorothalonil fire potential
Chlorothalonil is non-flammable and non-explosive.
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
Chlorothalonil storage and handling
Chlorothalonil safe storage
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Store in an area without drain or sewer access.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Chlorothalonil storage conditions
Keep in cool, dry, ventilated place.
Source: Hazardous Substances Data Bank (HSDB)
Chlorothalonil incompatible materials
Cyanides
Source: Hazardous Substances Data Bank (HSDB)
Chlorothalonil reactivity
CHLOROTHALONIL is stable in neutral or acidic aqueous media. May react violently with strong oxidizing acids [Farm Chemicals Handbook]. Incompatible with other oxidizing agents such as peroxides and epoxides. Breaks down slowly in basic aqueous media (half-life 38.1 days at pH 9). [Farm Chemicals Handbook].
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Chlorothalonil in the storage compatibility matrix →
11 · Questions
Chlorothalonil — frequently asked questions
What is the CAS number of Chlorothalonil?
The CAS number of Chlorothalonil is 1897-45-6. Its EC number is 217-588-1.
What is the chemical formula of Chlorothalonil?
The molecular formula of Chlorothalonil is C8Cl4N2 and its molecular weight is 265.9 g/mol.
What does a Chlorothalonil label have to show?
Under CLP Annex VI the label for Chlorothalonil carries the pictograms Skull and crossbones, Corrosion, Health hazard and Environment and the signal word is Danger.
Is Chlorothalonil flammable?
CLP Annex VI assigns Chlorothalonil no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Chlorothalonil a carcinogen?
CLP Annex VI assigns Chlorothalonil H351 — suspected of causing cancer. That is category 2: the evidence points that way but is not conclusive. IARC places it in Group 2B: possibly carcinogenic to humans.
What is the boiling point of Chlorothalonil?
The boiling point reported for Chlorothalonil is 350 °C (662 °F) (HSDB).
What is the melting point of Chlorothalonil?
The melting point reported for Chlorothalonil is 252.1 °C (485.8 °F) (HSDB).
How should Chlorothalonil be stored?
Keep in cool, dry, ventilated place. (Hazardous Substances Data Bank (HSDB))
Nearby
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