Substance profile
Clorofene
Clorofene is white to light tan or pink flakes with white to light tan or pink flakes odor.
01 · Identification
What Clorofene is
Clorofene is white to light tan or pink flakes with white to light tan or pink flakes odor. Its molecular formula is C13H11ClO and its molecular weight is 218.68 g/mol. It melts at 48.5 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Clorofene identifiers and molecular data
Clorofene CAS number and EC number
Clorofene molecular formula and molecular weight
Other names for Clorofene
- chlorophene
- 2-benzyl-4-chlorophenol
03 · GHS classification
Clorofene hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Clorofene pictograms and signal word
Clorofene hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - inhalation GHS chapter 3.1 | Category 4 | H332 | GHS07 |
| Skin corrosion/irritation GHS chapter 3.2 | Category 2 | H315 | GHS07 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 1 | H318 | GHS05 |
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
| Carcinogenicity GHS chapter 3.6 | Category 2 | H351 | GHS08 |
| Specific target organ toxicity - repeated exposure GHS chapter 3.9 | Category 2 | H373 | GHS08 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Clorofene hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H351 | Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H361f | Suspected of damaging fertility. |
| H332 | Harmful if inhaled. |
| H373 | May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H315 | Causes skin irritation. |
| H318 | Causes serious eye damage. |
| H317 | May cause an allergic skin reaction. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Clorofene. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Clorofene
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Clorofene issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Clorofene precautionary statements
CLP Annex VI assigns 23 precautionary statements to Clorofene. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Clorofene name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | клорофен хлорофен2-бензил-4-хлорофенол |
| Spanish español | Clorofeno 2-bencil-4-clorofenol |
| Czech čeština | chlorofen 2-benzyl-4-chlorfenol |
| Danish dansk | clorofen chlorphen 2-benzyl-4-chlorphenol |
| German Deutsch | Clorofen Chlorophen2-Benzyl-4-chlorphenol |
| Estonian eesti | klorofeen 2-bensüül-4-klorofenool |
| Greek ελληνικά | χλωροφαίνιο 2-βενζυλο-4-χλωροφαινόλη |
| English English | clorofene chlorophene2-benzyl-4-chlorophenol |
| French français | clorofene chlorophene2-benzyl-4-chlorophenol |
| Croatian hrvatski | klorofen 2-benzil-4-klorofenol |
| Italian italiano | clorofene 2-benzil-4-clorofenolo |
| Latvian latviešu | klorofēns hlorofēns2-benzil-4-hlorfenols |
| Lithuanian lietuvių | klorofenas chlorfenas2-benzil-4-chlorfenolis |
| Hungarian magyar | klorofén 2-benzil-4-klórfenol |
| Maltese Malti | clorofenum klorofen2-benżil-4-klorofenol |
| Dutch Nederlands | chlorofeen 2-benzyl-4-chloorfenol |
| Polish polski | chlorofen 2-benzylo-4-chlorofenol |
| Portuguese português | Clorofeno clorfeno2-benzil-4-clorofenol |
| Romanian română | clorofen 2-benzil-4-clorfenol |
| Slovak slovenčina | chlorofén 2-benzyl-4-chlórfenol |
| Slovenian slovenščina | klorofen 2-benzil-4-klorofenol |
| Finnish suomi | klorofeeni 2-bentsyyli-4-kloorifenoli |
| Swedish svenska | clorofene chlorophene2-benzyl-4-chlorophenol |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Clorofene GHS label elements
Everything CLP Annex VI fixes for Clorofene, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Clorofene
- Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Suspected of damaging fertility.
- Harmful if inhaled.
- May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Causes skin irritation.
- Causes serious eye damage.
- May cause an allergic skin reaction.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Obtain special instructions before use.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Wash … thoroughly after handling.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Contaminated work clothing should not be allowed out of the workplace.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF ON SKIN:
- IF INHALED:
- IF IN EYES:
- IF exposed or concerned:
- Immediately call a POISON CENTER/doctor/…
- Call a POISON CENTER/doctor/… if you feel unwell.
- Get medical advice/attention.
- Get medical advice/attention if you feel unwell.
- If skin irritation occurs:
- If skin irritation or rash occurs:
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Clorofene in the GHS label constructor →
07 · Health hazards
Clorofene health hazards and exposure limits
Clorofene hazard summary
Emergency medical treatment: see phenol and related agents; A skin irritant; One of the chemicals that can cause toxic vitiligo; [HSDB] Chemical leukoderma is indistinguishable from vitiligo; May occur in workers exposed to hydroquinones, catechols, phenols, or mercaptoamines; [White, p. 285] A mutagen, tumorigen, and mild skin irritant; Causes somnolence and convulsions in lethal-dose studies of mice; [RTECS] A skin, mucous membrane, and respiratory tract irritant; Corrosive to eyes; It has also caused severe porphyria cutanea tarda. [CAMEO] Chemical associated with acquired porphyria include hexachlorobenzene, 2,4-dichlorophenol, 2,4,5-trichlorophenol, 2,3,7,8-tetrachlorodibenzo-p-dioxin, o-benzyl-p-chlorophenol, 2-benzyl-p-dichlorophenol, vinyl chloride, lead, and aluminum; However, recent studies have failed to find an association between 2,3,7,8-tetrachlorodibenzo-p-dioxin and porphyrin levels; [LaDou, p. 266, 519] Corrosive to eyes; Causes kidney injury in chronic animal experiments and is a possible human carcinogen; [Reference #1] An irritant; Effects in high-dose animal studies include convulsions; [MSDSonline]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Clorofene carcinogenicity classification
Under the conditions of this 1-year mouse skin initiation/promotion study in Swiss (CD-1) mice, o -benzyl- p -chlorophenol was a cutaneous irritant and a weak skin tumor promoter relative to strong promoters such as TPA. BCP had no activity as an initiator or as a complete carcinogen.
Source: US National Toxicology Program · TR-444: One-Year Initiation/Promotion Study of o-Benzyl-p-Chlorophenol (CASRN 120-32-1) in Swiss (CD-1) Mice (Mouse Skin Study) (1995 )
Cancer Classification: Group C Possible Human Carcinogen
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
Clorofene properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Clorofene boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 161 °C (321.8 °F) | range, midpoint shown, at 3.5 mmHg (reduced pressure) | HSDB |
| 161.11 °C (322 °F) | range, midpoint shown, at 3.5 mmHg (reduced pressure) | CAMEO |
Clorofene melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 48.5 °C (119.3 °F) | HSDB |
Clorofene density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.22 g/cm³ | CAMEO | |
| 1.185 g/cm³ | at 58 °C | HSDB |
Clorofene solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Highly sol in alcohol and other org solvents | HSDB | |
| In water, 149 mg/L at 25 °C | at 25 °C | HSDB | |
| less than 1 mg/mL at 61 °F (NTP, 1992) | at 16.11 °C | CAMEO |
Clorofene vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.000001403 mmHg | HSDB | |
| 0.1 mmHg | at 20 °C | CAMEO | |
| 0.0000506 mmHg | Haz-Map |
Clorofene flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 187.78 °C (370 °F) | CAMEO |
Clorofene corrosivity
| Property | Value | Conditions | Source |
|---|---|---|---|
| Corrosivity | Noncorrosive to most metals | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
Clorofene fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Clorofene fire potential
Combustible
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
Clorofene storage and handling
Clorofene storage conditions
Safe Storage of Pesticides. Always store pesticides in their original containers, complete with labels that list ingredients, directions for use, and first aid steps in case of accidental poisoning. Never store pesticides in cabinets with or near food, animal feed, or medical supplies. Do not store pesticides in places where flooding is possible or in places where they might spill or leak into wells, drains, ground water, or surface water.
Source: Hazardous Substances Data Bank (HSDB)
Clorofene reactivity
ORTHO-BENZYL-PARA-CHLOROPHENOL is incompatible with acids and oxidizing agents (NTP, 1992). Is sensitive to light. Stable at temperatures up to 77 °F when protected from light, but storage at 140 °F causes decomposition.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Clorofene in the storage compatibility matrix →
11 · Questions
Clorofene — frequently asked questions
What is the CAS number of Clorofene?
The CAS number of Clorofene is 120-32-1. Its EC number is 204-385-8.
What is the chemical formula of Clorofene?
The molecular formula of Clorofene is C13H11ClO and its molecular weight is 218.68 g/mol.
What does a Clorofene label have to show?
Under CLP Annex VI the label for Clorofene carries the pictograms Health hazard, Corrosion, Exclamation mark and Environment and the signal word is Danger.
Is Clorofene flammable?
CLP Annex VI assigns Clorofene no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 187.78 °C (370 °F) (CAMEO).
Is Clorofene a carcinogen?
CLP Annex VI assigns Clorofene H351 — suspected of causing cancer. That is category 2: the evidence points that way but is not conclusive.
What is the boiling point of Clorofene?
The boiling point reported for Clorofene is 161 °C (321.8 °F), range, midpoint shown, at 3.5 mmHg (reduced pressure) (HSDB).
What is the melting point of Clorofene?
The melting point reported for Clorofene is 48.5 °C (119.3 °F) (HSDB).
How should Clorofene be stored?
Safe Storage of Pesticides. Always store pesticides in their original containers, complete with labels that list ingredients, directions for use, and first aid steps in case of accidental poisoning. Never store pesticides in cabinets with or near food, animal feed, or medical supplies. Do not store pesticides in places where flooding is possible or in places where they might spill or leak into wells, drains, ground water, or surface water. (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Clorofene
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