Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

Build a label

Substance profile

Clothianidin

Clothianidin is a colorless powder and is odorless.

CAS 210880-92-5 C6H8ClN5O2S 249.68 g/mol Danger

01 · Identification

What Clothianidin is

Clothianidin is a colorless powder and is odorless. Its molecular formula is C6H8ClN5O2S and its molecular weight is 249.68 g/mol. It melts at 177 °C.

Under the GHS it carries the signal word Danger.

02 · Identifiers

Clothianidin identifiers and molecular data

Clothianidin CAS number and EC number

CAS number210880-92-5
EC number433-460-1
Index number (CLP Annex VI)613-307-00-5

Clothianidin molecular formula and molecular weight

Molecular formulaC6H8ClN5O2S
Molecular weight249.68 g/mol

Other names for Clothianidin

  • clothianidin (ISO)
  • (E)-1-(2-chloro–1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine

03 · GHS classification

Clothianidin hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Clothianidin pictograms and signal word

Signal wordDanger

Clothianidin hazard class and category

GHS hazard classes Clothianidin falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 4 H302 GHS07
Specific target organ toxicity - single exposure GHS chapter 3.8 Category 1 H370 GHS08
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Clothianidin hazard statements (H-codes)

Hazard statements assigned to Clothianidin
CodeHazard statement
H361f Suspected of damaging fertility.
H302 Harmful if swallowed.
H370 Causes damage to organs <or state all organs affected, if known> <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Clothianidin. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Clothianidin

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Clothianidin issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Clothianidin precautionary statements

CLP Annex VI assigns 10 precautionary statements to Clothianidin. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Clothianidin name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български клотианидин (ISO) 2-метил-1-нитро-3-[(2-хлоро-1,3-тиазол-5-ил)метил]гуанидин
Spanish español Clotianidina (ISO) ( E )-1-(2-cloro-1,3-tiazol-5-ilmetil)-3-metil-2-nitroguanidina
Czech čeština klothianidin (ISO) ( E )-1-(2-chlor-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidin
Danish dansk clothianidin (ISO) (E)-1-(2-chlor-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidin
German Deutsch Clothianidin (ISO) (E)-1-(2-Chlor-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidin
Estonian eesti klotianidiin (ISO) ( E )-1-(2-kloro-1,3-tiasool-5-üülmetüül)-3-metüül-2-nitroguanidiin
Greek ελληνικά clothianidin (κλοθειανιδίνη) (ISO) (Ε)-1-(2-χλωρο-1,3-θειαζολ-5-υλομεθυλο)-3-μεθυλο-2-νιτρογουανιδίνη
English English clothianidin (ISO) (E)-1-(2-chloro–1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine
French français clothianidine (ISO) (E)-1-(2-chloro-1,3-thiazol-5-ylméthyl)-3-méthyl-2-nitroguanidine
Croatian hrvatski klotianidin (ISO) ( E )-1-(2-klor-1,3-tiazol-5-ilmetil)-3-metil-2-nitrogvanidin
Italian italiano clotianidina (ISO) (E)-1-(2-cloro-1,3-tiazol-5-ilmetil)-3-metil-2-nitroguanidina
Latvian latviešu klotianidīns (ISO) (E)-1-(2-hlor-1,3-tiazol-5-ilmetil)-3-metil-2-nitroguanidīns
Lithuanian lietuvių klotianidinas (ISO) (E)-1-(2-chlor-1,3-tiazol-5-ilmetil)-3-metil-2-nitroguanidinas
Hungarian magyar klotianidin (ISO) (E)-1-(2-klór-1,3-tiazol-5-ilmetil)-3-metil-2-nitroguanidin
Maltese Malti klotijanidina (ISO) ( E )-1-(2-kloro-1,3-tijażol-5-ilmetil)-3-metil-2-nitrogwanidina
Dutch Nederlands clothianidine (ISO) ( E )-1-(2-chloor-1,3-thiazool-5-ylmethyl)-3-methyl-2-nitroguanidine
Polish polski klotianidyna (ISO) ( E )-1-(2-chloro-1,3-tiazol-5-ylometylo)-3-metylo-2-nitroguanidyna
Portuguese português clotianidina (ISO) ( E )-1-(2-cloro-1,3-tiazol-5-ilmetil)-3-metil-2-nitroguanidina
Romanian română clotianidin (ISO) (E)-1-(2-cloro-1,3-tiazol-5-ilmetil)-3-metil-2-nitroguanidin
Slovak slovenčina klotianidín (ISO) ( E )-1-(2-chlór-1,3-tiazol-5-ylmetyl)-3-metyl-2-nitroguanidín
Slovenian slovenščina klotianidin (ISO) (E)-1-(2-kloro-1,3-tiazol-5-ilmetil)-3-metil-2-nitrogvanidin
Finnish suomi klotianidiini (ISO) (E)-1-(2-kloori-1,3-tiatsol-5-yylimetyyli)-3-metyyli-2-nitroguanidiini
Swedish svenska klotianidin (ISO) (E)-1-(2-klor-1,3-tiazol-5-ylmetyl)-3-metyl-2-nitroguanidin

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Clothianidin GHS label elements

Everything CLP Annex VI fixes for Clothianidin, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS08 Health hazard pictogramGHS07 Exclamation mark pictogramGHS09 Environment pictogram

Danger

Clothianidin

  • Suspected of damaging fertility.
  • Harmful if swallowed.
  • Causes damage to organs <or state all organs affected, if known> <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Avoid release to the environment.
  • IF SWALLOWED:
  • IF exposed or concerned:
  • Call a POISON CENTER/doctor/
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Rinse mouth.
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Clothianidin in the GHS label constructor →

07 · Physical and chemical properties

Clothianidin properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Clothianidin melting point

Property Value Conditions Source
Melting point 176.8 °C (350.2 °F) HSDB

Clothianidin density

Property Value Conditions Source
Density 1.2632 g/cm³ End-use HSDB
1.61 g/cm³ at 20 °C HSDB

Clothianidin solubility

Property Value Conditions Source
Solubility In water, 0.304 (pH 4), 0.340 (pH 10) (both g/L, 20 °C) at 20 °C HSDB
In water, 327 mg/L at 20 °C at 20 °C HSDB
In heptane less than 0.00104, xylene 0.0128, dichloromethane 1.32, methanol 6.26, octanol 0.938, acetone 15.2, ethyl acetate 2.03 (all in g/L, 25 °C) at 25 °C HSDB

Clothianidin vapor pressure

Property Value Conditions Source
Vapor pressure 0.0009751 mmHg at 25 °C HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

08 · Handling and storage

Clothianidin storage and handling

Clothianidin storage conditions

Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): 13: Non Combustible Solids.

Source: Hazardous Substances Data Bank (HSDB)

Clothianidin incompatible materials

Incompatible materials: Strong oxidizing agents.

Source: Hazardous Substances Data Bank (HSDB)

Planning storage for a mix of chemicals? Check Clothianidin in the storage compatibility matrix →

09 · Questions

Clothianidin — frequently asked questions

What is the CAS number of Clothianidin?

The CAS number of Clothianidin is 210880-92-5. Its EC number is 433-460-1.

What is the chemical formula of Clothianidin?

The molecular formula of Clothianidin is C6H8ClN5O2S and its molecular weight is 249.68 g/mol.

What does a Clothianidin label have to show?

Under CLP Annex VI the label for Clothianidin carries the pictograms Health hazard, Exclamation mark and Environment and the signal word is Danger.

Is Clothianidin flammable?

CLP Annex VI assigns Clothianidin no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is Clothianidin a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Clothianidin. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the melting point of Clothianidin?

The melting point reported for Clothianidin is 176.8 °C (350.2 °F) (HSDB).

How should Clothianidin be stored?

Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): 13: Non Combustible Solids. (Hazardous Substances Data Bank (HSDB))

Get the free GHS / CLP / OSHA deadline calendar

Verified 2026–2029 compliance dates in one PDF — plus alerts when the rules change.