Substance profile
Dicoumarol
Dicoumarol is a white or creamy white, crystalline powder with a slight, pleasant odor.
01 · Identification
What Dicoumarol is
Dicoumarol is a white or creamy white, crystalline powder with a slight, pleasant odor. Its molecular formula is C19H12O6 and its molecular weight is 336.3 g/mol. It melts at 290 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Dicoumarol identifiers and molecular data
Dicoumarol CAS number and EC number
Dicoumarol molecular formula and molecular weight
Other names for Dicoumarol
- 4,4'-dihydroxy-3,3'-methylenebis(2H-chromen-2-one)
03 · GHS classification
Dicoumarol hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Dicoumarol pictograms and signal word
Dicoumarol hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
| Specific target organ toxicity - repeated exposure GHS chapter 3.9 | Category 1 | H372 | GHS08 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 2 | H411 | GHS09 |
Dicoumarol hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H302 | Harmful if swallowed. |
| H372 | Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H411 | Toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Dicoumarol. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Dicoumarol
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Dicoumarol issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Dicoumarol precautionary statements
CLP Annex VI assigns 9 precautionary statements to Dicoumarol. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Dicoumarol name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | дикумарол 4,4′-дихидрокси-3,3′-метиленбис(2 Н -хромен-2-он) |
| Spanish español | Dicumarol 4,4'-dihidroxi-3,3'-metilenbis(2 H -cromen-2-ona) |
| Czech čeština | dikumarol 4,4'-dihydroxy-3,3'-methylendi(2 H -chromen-2-on) |
| Danish dansk | dicumarol 4,4'-dihydroxy-3,3' methylenbis(2 H- chromen-2-on) |
| German Deutsch | Dicoumarol 4,4'-Dihydroxy-3,3'-methylenbis(2 H -chromen-2-on) |
| Estonian eesti | dikumarool 4,4'-dihüdroksü-3,3'-metüleenbis(2 H -kromeen-2-oon) |
| Greek ελληνικά | δικουμαρόλη 4,4′-διυδροξυ-3,3′-μεθυλενοδις(2 H -χρωμεν-2-όνη) |
| English English | dicoumarol 4,4'-dihydroxy-3,3'-methylenebis(2 H -chromen-2-one) |
| French français | dicoumarol 4,4'-dihydroxy-3,3'-méthylènebis(2 H -chromén-2-one) |
| Croatian hrvatski | dikumarol 4,4'-dihidroksi-3,3'-metilenbis(2 H -kromen-2-on) |
| Italian italiano | dicumarolo 4,4'-diidrossi-3,3'-metilenebis(2 H -cromen-2-one) |
| Latvian latviešu | dikumarols 4,4′-dihidroksi-3,3′-metilēnbis(2 H -hromēn-2-ons) |
| Lithuanian lietuvių | dikumarolis 4,4’-dihidroksi-3,3’-metilenbis(2 H -chromen-2-onas) |
| Hungarian magyar | dikumarol 4,4’-dihidroxi-3,3’-metilénbisz(2 H -kromén-2-on) |
| Maltese Malti | dikowmarol 4,4'-diidrossi-3,3'-metilenebis(2 H -kromen-2-on) |
| Dutch Nederlands | dicumarol 4,4'-dihydroxy-3,3'-methyleenbis(2 H -chromeen-2-on) |
| Polish polski | dikumarol 4,4'-dihydroksy-3,3'-metylenobis(2 H -chromen-2-on)3,3'-metylenobis(4-hydroksy-2-okso-2 H -chromen) |
| Portuguese português | dicumarol 4,4'-di-hidroxi-3,3'-metilenobis(2 H -cromen-2-ona) |
| Romanian română | dicumarol 4,4'-dihidroxi-3,3'-metilenbis (2 H -cromen-2-onă) |
| Slovak slovenčina | dikumarol 4,4'-dihydroxy-3,3'-metylénbis(2 H chromén- 2-ón) |
| Slovenian slovenščina | dikumarol 4,4'-dihidroksi-3,3'-metilenbis(2 H -kromen-2-on) |
| Finnish suomi | dikumariini 4,4'-dihydroksi-3,3'-metyleenibis(2 H -kromen-2-oni) |
| Swedish svenska | dikumarol 4,4'-dihydroxi-3,3'-metylenbis(2 H -kromen-2-on) |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Dicoumarol GHS label elements
Everything CLP Annex VI fixes for Dicoumarol, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Dicoumarol
- Harmful if swallowed.
- Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Toxic to aquatic life with long lasting effects.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Avoid release to the environment.
- IF SWALLOWED:
- Call a POISON CENTER/doctor/… if you feel unwell.
- Get medical advice/attention if you feel unwell.
- Rinse mouth.
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Dicoumarol in the GHS label constructor →
07 · Health hazards
Dicoumarol health hazards and exposure limits
Dicoumarol hazard summary
A vitamin K antagonist--disrupts clotting factors and causes bleeding; May cause reproductive toxicity; [HSDB] See Warfarin.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
Dicoumarol properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Dicoumarol melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 290 °C (554 °F) | range, midpoint shown | HSDB |
| 290 °C (554 °F) | HMDB |
Dicoumarol solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Practically insol in water, alc, ether. | HSDB | |
| INSOL IN ACETONE | HSDB | ||
| Sol in aq alkaline solns, in pyridine and similar org bases. Slightly sol in benzene and chloroform. | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Dicoumarol storage and handling
Dicoumarol storage conditions
Dicumarol should be stored in well-closed containers at a temperature below 40 degrees C (104 °F), preferably 15 to 30 °C (59 to 86 °F), and kept away from direct sunlight. The manufacturer recommends storage below 25 °C (77 °F).
Source: Hazardous Substances Data Bank (HSDB)
Planning storage for a mix of chemicals? Check Dicoumarol in the storage compatibility matrix →
10 · Questions
Dicoumarol — frequently asked questions
What is the CAS number of Dicoumarol?
The CAS number of Dicoumarol is 66-76-2. Its EC number is 200-632-9.
What is the chemical formula of Dicoumarol?
The molecular formula of Dicoumarol is C19H12O6 and its molecular weight is 336.3 g/mol.
What does a Dicoumarol label have to show?
Under CLP Annex VI the label for Dicoumarol carries the pictograms Health hazard, Exclamation mark and Environment and the signal word is Danger.
Is Dicoumarol flammable?
CLP Annex VI assigns Dicoumarol no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Dicoumarol a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Dicoumarol. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the melting point of Dicoumarol?
The melting point reported for Dicoumarol is 290 °C (554 °F), range, midpoint shown (HSDB).
How should Dicoumarol be stored?
Dicumarol should be stored in well-closed containers at a temperature below 40 degrees C (104 °F), preferably 15 to 30 °C (59 to 86 °F), and kept away from direct sunlight. The manufacturer recommends storage below 25 °C (77 °F). (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Dicoumarol
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