Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Dicrotophos

Dicrotophos is a yellowish liquid with a mild, ester odor.

CAS 141-66-2 C8H16NO5P 237.19 g/mol Danger

01 · Identification

What Dicrotophos is

Dicrotophos is a yellowish liquid with a mild, ester odor. Its molecular formula is C8H16NO5P and its molecular weight is 237.19 g/mol. It boils at 400 °C, is miscible with water.

Under the GHS it carries the signal word Danger.

02 · Identifiers

Dicrotophos identifiers and molecular data

Dicrotophos CAS number and EC number

CAS number141-66-2
EC number205-494-3
Index number (CLP Annex VI)015-073-00-4

Dicrotophos molecular formula and molecular weight

Molecular formulaC8H16NO5P
Molecular weight237.19 g/mol

Other names for Dicrotophos

  • dicrotophos (ISO)
  • (Z)-2-dimethylcarbamoyl-1-methylvinyl dimethyl phosphate

03 · GHS classification

Dicrotophos hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Dicrotophos pictograms and signal word

Signal wordDanger

Dicrotophos hazard class and category

GHS hazard classes Dicrotophos falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 1 or 2 H300 GHS06
Acute toxicity - dermal GHS chapter 3.1 Category 3 H311 GHS06
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

Dicrotophos hazard statements (H-codes)

Hazard statements assigned to Dicrotophos
CodeHazard statement
H300 Fatal if swallowed.
H311 Toxic in contact with skin.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Dicrotophos. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Dicrotophos

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Dicrotophos issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Dicrotophos precautionary statements

CLP Annex VI assigns 10 precautionary statements to Dicrotophos. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Dicrotophos name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български дикротофос (ISO) ( Z )-2-диметилкарбамоил-1-метилвинилов диметилов фосфат
Spanish español Dicrotofós (ISO) fosfato de ( Z )-2-dimetilcarbamoil-1-metilvinilo y dimetilo
Czech čeština dikrotofos (ISO) (Z)-[1-(N, N-dimethylkarbamoyl)prop-1-en-2-yl]-dimethyl-fosfát
Danish dansk dicrotophos (ISO) (Z)-2-dimethylcarbamoyl-1-methylvinyldimethylphosphat
German Deutsch Dicrotophos (ISO) ( Z )-2-Dimethylcarbamoyl-1-methylvinyldimethylphosphat
Estonian eesti dikrotofoss (ISO) ( Z )-2-dimetüülkarbamoüül-1-metüülvinüüldimetüülfosfaat
Greek ελληνικά dicrotophos (δικροτοφός) (ISO) φωσφορικό ( Ζ )-2-διμεθυλοκαρβαμοϋλο-1-μεθυλοβινύλιο διμεθύλιο
English English dicrotophos (ISO) ( Z )-2-dimethylcarbamoyl-1-methylvinyl dimethyl phosphate
French français dicrotophos (ISO) phosphate de ( Z )-2-diméthylcarbamoyl-1-méthylvinyle et de diméthyle
Croatian hrvatski dikrotofos (ISO) ( Z )-2-dimetil-karbamoil-1-metil-vinil-dimetil-fosfat
Italian italiano dicrotofos (ISO) fosfato di (Z)-2-dimetilcarbammoil-1-metilvinile e dimetile
Latvian latviešu dikrotofoss (ISO) ( Z )-2-dimetilkarbamoil-1-metilvinildimetilfosfāts
Lithuanian lietuvių dikrotofosas (ISO) ( Z )-2-dimetilkarbamoil-1-metilvinildimetilfosfatas
Hungarian magyar dikrotofosz (ISO) ( Z )-2-dimetilkarbamoil-1-metilvinil-dimetil-foszfát
Maltese Malti dikrotofos (ISO) fosfat tad-dimetil ta’ ( Z )-2-dimetilkarbamojl-1-metilvinil
Dutch Nederlands dicrotofos (ISO) ( Z )-2-dimethylcarbamoyl-1-methylvinyldimethylfosfaat
Polish polski dikrotofos (ISO) fosforan ( E )-2-(dimetylokarbamoilo)-1-metylowinylu-dimetylu
Portuguese português dicrotofos (ISO) fosfato de ( Z )-2-dimetilcarbamoil-1-metilvinilo e de dimetilo
Romanian română dicrotofos (ISO) fosfat de ( Z )-2-dimetilcarbamoil-1- metilvinil și de dimetil
Slovak slovenčina dikrotofos (ISO) ( Z )-[2-(dimetylkarbamoyl)-1-metylvinyl]- dimetyl-fosfát
Slovenian slovenščina dikrotofos (ISO) ( Z )-2-dimetilkarbamoil-1-metilvinil dimetil fosfat
Finnish suomi dikrotofossi (ISO) ( Z )-2-dimetyylikarbamoyyli-1-metyylivinyylidimetyylifosfaatti
Swedish svenska dikrotofos (ISO) ( Z )-2-dimetylkarbamoyl-1-metylvinyldimetylfosfat

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Dicrotophos GHS label elements

Everything CLP Annex VI fixes for Dicrotophos, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS06 Skull and crossbones pictogramGHS09 Environment pictogram

Danger

Dicrotophos

  • Fatal if swallowed.
  • Toxic in contact with skin.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Do not eat, drink or smoke when using this product.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • Immediately call a POISON CENTER/doctor/
  • Rinse mouth.
  • Wash with plenty of water/
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Dicrotophos in the GHS label constructor →

07 · Health hazards

Dicrotophos health hazards and exposure limits

Dicrotophos hazard summary

It is classified as moderately toxic and may be used only by certified applicators. [EXTOXNET] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Dicrotophos carcinogenicity classification

Cancer Classification: Suggestive Evidence of Carcinogenicity, but Not Sufficient to Assess Human Carcinogenic Potential

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

Dicrotophos occupational exposure limits

US occupational exposure limits reported for Dicrotophos. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL none See Appendix G The National Institute for Occupational Safety and Health (NIOSH)
REL 0.25 mg/m³ Occupational Safety and Health Administration (OSHA)
REL TWA 0.25 mg/m3 [skin] The National Institute for Occupational Safety and Health (NIOSH)
IDLH N.D. The National Institute for Occupational Safety and Health (NIOSH)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

Dicrotophos properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Dicrotophos boiling point

Property Value Conditions Source
Boiling point 400 °C (752 °F) at 760 mmHg HSDB
400 °C (752 °F) NIOSH

Dicrotophos density

Property Value Conditions Source
Density 1.216 g/cm³ at 15 °C HSDB

Dicrotophos solubility

Property Value Conditions Source
Solubility Totally miscible with acetone, alcohols, acetonitrile, chloroform, dichlorormethane, xylene; very slightly soluble (<10 g/kg) in diesel oil, kerosene HSDB
Miscible with carbon tetracloride HSDB
MISCIBLE WITH HEXYLENE GLYCOL HSDB

Dicrotophos vapor pressure

Property Value Conditions Source
Vapor pressure 0.0001 mmHg NIOSH
0.00001 mmHg at 20 °C CAMEO
159800 mmHg at 25 °C HSDB

Dicrotophos flash point

Property Value Conditions Source
Flash point 93.33 °C (200 °F) above this value HSDB
93 °C (199.4 °F) above this value ICSC

Dicrotophos lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) Class IIIB Combustible Liquid: Fl.P. at or above 200 °F. NIOSH

Dicrotophos corrosivity

Property Value Conditions Source
Corrosivity Corrosive to cast iron, mild steel, brass, and stainless steel. HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

Dicrotophos storage and handling

Dicrotophos safe storage

Separated from food and feedstuffs. Keep in a well-ventilated room. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Dicrotophos storage conditions

Do not ... store in or around home. Avoid food, feed products. Keep away from heat and open flame.

Source: Hazardous Substances Data Bank (HSDB)

Dicrotophos incompatible materials

Attacks some metals.

Source: Hazardous Substances Data Bank (HSDB)

Dicrotophos reactivity

Organophosphates, such as DICROTOPHOS, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. This compound is incompatible with the following: Metals [Note: Corrosive to cast iron, mild steel, brass & stainless steel.] (NIOSH, 2024).

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Dicrotophos in the storage compatibility matrix →

10 · Questions

Dicrotophos — frequently asked questions

What is the CAS number of Dicrotophos?

The CAS number of Dicrotophos is 141-66-2. Its EC number is 205-494-3.

What is the chemical formula of Dicrotophos?

The molecular formula of Dicrotophos is C8H16NO5P and its molecular weight is 237.19 g/mol.

What does a Dicrotophos label have to show?

Under CLP Annex VI the label for Dicrotophos carries the pictograms Skull and crossbones and Environment and the signal word is Danger.

Is Dicrotophos flammable?

CLP Annex VI assigns Dicrotophos no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 93.33 °C (200 °F), above this value (HSDB).

Is Dicrotophos a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Dicrotophos. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the exposure limit for Dicrotophos?

The US occupational exposure limit reported for Dicrotophos is none See Appendix G (The National Institute for Occupational Safety and Health (NIOSH)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the boiling point of Dicrotophos?

The boiling point reported for Dicrotophos is 400 °C (752 °F), at 760 mmHg (HSDB).

How should Dicrotophos be stored?

Do not ... store in or around home. Avoid food, feed products. Keep away from heat and open flame. (Hazardous Substances Data Bank (HSDB))

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