Substance profile
Dimethyl Disulfide
Dimethyl Disulfide is a yellow liquid with a garlic-like odor.
01 · Identification
What Dimethyl Disulfide is
Dimethyl Disulfide is a yellow liquid with a garlic-like odor. It boils at 110 °C, melts at -84.7 °C, is practically insoluble in water.
Under the GHS it carries the signal word Danger. It is classed as flammable agents - 3rd degree.
02 · Identifiers
Dimethyl Disulfide identifiers and molecular data
Dimethyl Disulfide CAS number and EC number
Dimethyl Disulfide molecular formula and molecular weight
Other names for Dimethyl Disulfide
- dimethyl disulphide
03 · GHS classification
Dimethyl Disulfide hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Dimethyl Disulfide pictograms and signal word
Dimethyl Disulfide hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Flammable liquids GHS chapter 2.6 | Category 2 | H225 | GHS02 |
| Acute toxicity - oral GHS chapter 3.1 | Category 3 | H301 | GHS06 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 3 | H331 | GHS06 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 2A | H319 | GHS07 |
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 3 narcotic | H336 | GHS07 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 1 | H370 | GHS08 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Dimethyl Disulfide hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H225 | Highly flammable liquid and vapour. |
| H331 | Toxic if inhaled. |
| H301 | Toxic if swallowed. |
| H336 | May cause drowsiness or dizziness. |
| H370 | Causes damage to organs <or state all organs affected, if known> <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H319 | Causes serious eye irritation. |
| H317 | May cause an allergic skin reaction. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Dimethyl Disulfide. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Dimethyl Disulfide
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Dimethyl Disulfide issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Dimethyl Disulfide precautionary statements
CLP Annex VI assigns 26 precautionary statements to Dimethyl Disulfide. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Dimethyl Disulfide name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | диметилдисулфид |
| Spanish español | Disulfuro de dimetilo |
| Czech čeština | dimethyl-disulfid |
| Danish dansk | dimethyldisulphid |
| German Deutsch | Dimethyldisulfid |
| Estonian eesti | Dimetüüldisulfiid |
| Greek ελληνικά | διμεθυλοδισουλφίδιο |
| English English | dimethyl disulphide |
| French français | disulfure de diméthyle |
| Croatian hrvatski | dimetil disulfid |
| Italian italiano | dimetil disolfuro |
| Latvian latviešu | dimetildisulfīds |
| Lithuanian lietuvių | dimetildisulfidas |
| Hungarian magyar | dimetil-diszulfid |
| Maltese Malti | disulfur tad-dimetil |
| Dutch Nederlands | dimethyldisulfide |
| Polish polski | disiarczek dimetylu |
| Portuguese português | dissulfureto de dimetilo |
| Romanian română | disulfură de dimetil |
| Slovak slovenčina | dimetyldisulfán |
| Slovenian slovenščina | dimetil disulfid |
| Finnish suomi | dimetyylidisulfidi |
| Swedish svenska | dimetyldisulfid |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Dimethyl Disulfide GHS label elements
Everything CLP Annex VI fixes for Dimethyl Disulfide, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Dimethyl Disulfide
- Highly flammable liquid and vapour.
- Toxic if inhaled.
- Toxic if swallowed.
- May cause drowsiness or dizziness.
- Causes damage to organs <or state all organs affected, if known> <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Causes serious eye irritation.
- May cause an allergic skin reaction.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- Keep container tightly closed.
- Use explosion-proof [electrical/ventilating/lighting/…] equipment.
- Use only non-sparking tools.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Wash … thoroughly after handling.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Contaminated work clothing should not be allowed out of the workplace.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF INHALED:
- IF IN EYES:
- IF exposed or concerned:
- Immediately call a POISON CENTER/doctor/…
- Call a POISON CENTER/doctor/…
- Get medical advice/attention.
- Rinse mouth.
- If skin irritation or rash occurs:
- If eye irritation persists:
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Collect spillage.
- Store in a well-ventilated place.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Dimethyl Disulfide in the GHS label constructor →
07 · Health hazards
Dimethyl Disulfide health hazards and exposure limits
Dimethyl Disulfide hazard summary
A mild skin irritant, dimethyl disulfide is toxic by inhalation, skin absorption, and ingestion. Workers are warned by the nauseating odor, but those exposed to high concentrations may experience fatigue, dyspnea, and upper respiratory tract irritation. At lethal concentrations, animals suffer severe lung injury and paralysis of respiratory muscles. [CHEMINFO] Showed weak to moderate sensitizing potential in local lymph node assay (LLNA) of mice; [EPA - TSCATS]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
Dimethyl Disulfide properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Dimethyl Disulfide boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 109.72 °C (229.5 °F) | HSDB | |
| 109.72 °C (229.5 °F) | at 760 mmHg | CAMEO | |
| 110 °C (230 °F) | ICSC |
Dimethyl Disulfide melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -84.67 °C (-120.4 °F) | HSDB | |
| -84.72 °C (-120.5 °F) | CAMEO | ||
| -85 °C (-121 °F) | ICSC |
Dimethyl Disulfide density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.06 g/cm³ | ICSC | |
| 1.0625 g/cm³ | at 20 °C | HSDB | |
| 1.065 g/cm³ | at 20 °C | CAMEO |
Dimethyl Disulfide solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Insoluble in water | HSDB | |
| Miscible with ethanol, ethyl ether | HSDB | ||
| Completely miscible with most organic solvents | HSDB |
Dimethyl Disulfide vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 28.7 mmHg | at 25 °C | HSDB |
| 28.6 mmHg | at 25 °C | CAMEO | |
| 28.5023 mmHg | at 25 °C | ICSC |
Dimethyl Disulfide flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 24 °C (75.2 °F) | closed cup | HSDB |
| 24.44 °C (76 °F) | CAMEO | ||
| 10 °C (50 °F) | ICSC |
Dimethyl Disulfide autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 300 °C (572 °F) | above this value | ICSC |
Dimethyl Disulfide lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | 1.1 % by volume | ICSC |
Dimethyl Disulfide upper explosive limit (UEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Upper explosive limit (UEL) | 16 % by volume | ICSC |
Dimethyl Disulfide vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 3.24 (air = 1) | HSDB | |
| 3.2 (air = 1) | ICSC |
Dimethyl Disulfide odor threshold
| Property | Value | Conditions | Source |
|---|---|---|---|
| Odor threshold | 0.029 mg/cu m (recognition in air) | HSDB | |
| 0.003-0.014 mg/cu m (detection in air) | HSDB | ||
| 3X10-3 ppm in water | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
Dimethyl Disulfide fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Dimethyl Disulfide fire potential
A very dangerous fire hazard when exposed to heat, flame, or oxidizers.
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
Dimethyl Disulfide storage and handling
Dimethyl Disulfide safe storage
Fireproof. Well closed. Separated from oxidants. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Dimethyl Disulfide incompatible materials
... Can react vigorously with oxidizing materials.
Source: Hazardous Substances Data Bank (HSDB)
Dimethyl Disulfide reactivity
DIMETHYL DISULFIDE is a reducing agent. A dangerous fire hazard when exposed to oxidizing materials. Emits toxic fumes of oxides of sulfur when heated to decomposition or on contact with acids [Sax, 9th ed., 1996, p. 1320].
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Dimethyl Disulfide in the storage compatibility matrix →
11 · Transport
Dimethyl Disulfide UN number and transport classification
Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.
Dimethyl Disulfide under UN 2381 — shipping name, class and packing group
Europe · ADR 2025, Table A
| Proper shipping name (3.1.2) | Class | Classification code | PG | Labels (column 5) |
|---|---|---|---|---|
| DIMETHYL DISULPHIDE | 3 | FT1 | II | |
Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 3 is “Flammable liquids” (ADR 2.1.1.1).
United States · 49 CFR 172.101 Hazardous Materials Table
| Proper shipping name (column 2) | Class or division | PG | Labels (column 6) |
|---|---|---|---|
| Dimethyl disulfide | 3 | II | |
Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 3 is “Flammable and combustible liquid” (49 CFR 173.2).
12 · Questions
Dimethyl Disulfide — frequently asked questions
What is the CAS number of Dimethyl Disulfide?
The CAS number of Dimethyl Disulfide is 624-92-0. Its EC number is 210-871-0.
What does a Dimethyl Disulfide label have to show?
Under CLP Annex VI the label for Dimethyl Disulfide carries the pictograms Flame, Skull and crossbones, Health hazard and Environment and the signal word is Danger.
Is Dimethyl Disulfide flammable?
Yes. CLP Annex VI assigns Dimethyl Disulfide H225 — highly flammable liquid and vapour. The flash point reported for it is 24 °C (75.2 °F), closed cup (HSDB).
Is Dimethyl Disulfide a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Dimethyl Disulfide. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of Dimethyl Disulfide?
The boiling point reported for Dimethyl Disulfide is 109.72 °C (229.5 °F) (HSDB).
What is the melting point of Dimethyl Disulfide?
The melting point reported for Dimethyl Disulfide is -84.67 °C (-120.4 °F) (HSDB).
How should Dimethyl Disulfide be stored?
CLP Annex VI assigns Dimethyl Disulfide the storage statement P403.
Nearby
Substances next to Dimethyl Disulfide
Keep going: substances starting with D, or search the whole database by name, CAS number, pictogram or signal word.