Substance profile
Dimethylcarbamoyl Chloride
Dimethylcarbamoyl Chloride is a clear, colorless liquid.
01 · Identification
What Dimethylcarbamoyl Chloride is
Dimethylcarbamoyl Chloride is a clear, colorless liquid. Its molecular formula is C3H6ClNO and its molecular weight is 107.54 g/mol. It boils at 167 °C, melts at -33 °C.
Under the GHS it carries the signal word Danger. It is classed as hazardous Air Pollutants (HAPs).
02 · Identifiers
Dimethylcarbamoyl Chloride identifiers and molecular data
Dimethylcarbamoyl Chloride CAS number and EC number
Dimethylcarbamoyl Chloride molecular formula and molecular weight
03 · GHS classification
Dimethylcarbamoyl Chloride hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Dimethylcarbamoyl Chloride pictograms and signal word
Dimethylcarbamoyl Chloride hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 3 | H331 | GHS06 |
| Skin corrosion/irritation GHS chapter 3.2 | Category 2 | H315 | GHS07 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 2A | H319 | GHS07 |
| Carcinogenicity GHS chapter 3.6 | Category 1A or 1B | H350 | GHS08 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 3 | H335 | GHS07 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Dimethylcarbamoyl Chloride hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H350 | May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H331 | Toxic if inhaled. |
| H302 | Harmful if swallowed. |
| H335 | May cause respiratory irritation. |
| H315 | Causes skin irritation. |
| H319 | Causes serious eye irritation. |
This page lists only the codes assigned to Dimethylcarbamoyl Chloride. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Dimethylcarbamoyl Chloride
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Dimethylcarbamoyl… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Dimethylcarbamoyl Chloride precautionary statements
CLP Annex VI assigns 19 precautionary statements to Dimethylcarbamoyl Chloride. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Dimethylcarbamoyl Chloride name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | диметилкарбамоилхлорид |
| Spanish español | Cloruro de dimetilcarbamoílo |
| Czech čeština | N, N -dimethylkarbamoylchlorid |
| Danish dansk | dimethylcarbamoylchlorid |
| German Deutsch | Dimethylcarbamoylchlorid Dimethylcarbamidsäurechlorid |
| Estonian eesti | dimetüülkarbamoüülkloriid |
| Greek ελληνικά | διμεθυλοκαρβαμοϋλοχλωρίδιο |
| English English | dimethylcarbamoyl chloride |
| French français | chlorure de diméthylcarbamoyle |
| Croatian hrvatski | dimetil-karbamoil klorid |
| Italian italiano | dimetilcarbamoil cloruro |
| Latvian latviešu | dimetilkarbamoilhlorīds |
| Lithuanian lietuvių | dimetbilkarbamoilchloridas |
| Hungarian magyar | dimetil-karbamoil-klorid |
| Maltese Malti | klorur tad-dimetilkarbamojl |
| Dutch Nederlands | dimethylcarbamoylchloride |
| Polish polski | chlorek dimetylokarbamoilu |
| Portuguese português | cloreto de dimetilcarbamoílo |
| Romanian română | clorură de dimetilcarbamoil |
| Slovak slovenčina | dimetylkarbamoylchlorid |
| Slovenian slovenščina | dimetilkarbamoil klorid |
| Finnish suomi | dimetyylikarbamyylikloridi |
| Swedish svenska | dimetylkarbamoylklorid |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Dimethylcarbamoyl Chloride GHS label elements
Everything CLP Annex VI fixes for Dimethylcarbamoyl Chloride, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Dimethylcarbamoyl Chloride
- May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Toxic if inhaled.
- Harmful if swallowed.
- May cause respiratory irritation.
- Causes skin irritation.
- Causes serious eye irritation.
- Obtain special instructions before use.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Wash … thoroughly after handling.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF INHALED:
- IF IN EYES:
- IF exposed or concerned:
- Immediately call a POISON CENTER/doctor/…
- Call a POISON CENTER/doctor/… if you feel unwell.
- Get medical advice/attention.
- Rinse mouth.
- If skin irritation occurs:
- If eye irritation persists:
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Wash with plenty of water/…
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Dimethylcarbamoyl Chloride in the GHS label constructor →
07 · Health hazards
Dimethylcarbamoyl Chloride health hazards and exposure limits
Dimethylcarbamoyl Chloride hazard summary
Dimethylcarbamoyl chloride is used as an intermediate in the production of pharmaceuticals, pesticides, and dyes. Acute (short-term) inhalation exposure to dimethylcarbamoyl chloride has been observed to result in damaged mucous membranes of the nose, throat, and lungs, and cause difficulty in breathing in rats. No information is available on the chronic (long-term), reproductive, developmental, or carcinogenic health effects of dimethylcarbamoyl chloride in humans. Nasal tract carcinomas have been observed in rats and male hamsters following inhalation exposure. EPA has not classified dimethylcarbamoyl chloride for potential carcinogenicity.
Source: EPA Hazardous Air Pollutants
Dimethylcarbamoyl Chloride carcinogenicity classification
The Human Health Assessment Group in EPA's Office of Health and Environmental Assessment has evaluated dimethylcarbamoyl chloride carcinogenicity. According to their analysis, the weight-of-evidence for dimethylcarbamoyl chloride is group B2, which is based on inadequate evidence in humans and sufficient evidence in animals. As a group B2 chemical, dimethylcarbamoyl chloride is considered to be probably carcinogenic to humans.
Source: Hazardous Substances Data Bank (HSDB)
Evaluation: There is inadequate evidence in humans for the carcinogenicity of dimethylcarbamoyl chloride. There is sufficient evidence in experimental animals for the carcinogenicity of dimethylcarbamoyl chloride. Overall evaluation: Dimethylcarbamoyl chloride is probably carcinogenic to humans (Group 2A). In making the overall evaluation, the Working Group took into consideration that dimethylcarbamoyl chloride is a direct acting alkylating agent with a wide spectrum of genotoxic activity, including activity in somatic cells in vivo.
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
Dimethylcarbamoyl Chloride occupational exposure limits
| Limit | Value | Source |
|---|---|---|
| PEL | none | The National Institute for Occupational Safety and Health (NIOSH) |
| REL | Ca See Appendix A | The National Institute for Occupational Safety and Health (NIOSH) |
| IDLH | A potential occupational carcinogen. (NIOSH, 2024) | CAMEO Chemicals |
| IDLH | NIOSH recommends that dimethyl carbamoyl chloride be regulated as a potential human carcinogen. | Hazardous Substances Data Bank (HSDB) |
| IDLH | Ca [N.D.] | The National Institute for Occupational Safety and Health (NIOSH) |
These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.
08 · Physical and chemical properties
Dimethylcarbamoyl Chloride properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Dimethylcarbamoyl Chloride boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 167 °C (332.6 °F) | HSDB | |
| 165 °C (329 °F) | NIOSH |
Dimethylcarbamoyl Chloride melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -33 °C (-27.4 °F) | HSDB | |
| -32.78 °C (-27 °F) | NIOSH |
Dimethylcarbamoyl Chloride density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.17 g/cm³ | NIOSH | |
| 1.168 g/cm³ | at 20 °C | CAMEO | |
| 1.168 g/cm³ | at 25 °C | HSDB |
Dimethylcarbamoyl Chloride solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Reacts | NIOSH | |
| Decomposes (NTP, 1992) | decomposes | CAMEO |
Dimethylcarbamoyl Chloride vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 1.95 mmHg | at 25 °C | HSDB |
| 1.95 mmHg | Haz-Map |
Dimethylcarbamoyl Chloride flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 68.33 °C (155 °F) | NIOSH |
Dimethylcarbamoyl Chloride lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | Class IIIA Combustible Liquid: Fl.P. at or above 140 °F and below 200 °F. | NIOSH |
Dimethylcarbamoyl Chloride vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 3.73 (air = 1) | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Dimethylcarbamoyl Chloride storage and handling
Dimethylcarbamoyl Chloride storage conditions
PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/
Source: Hazardous Substances Data Bank (HSDB)
Dimethylcarbamoyl Chloride incompatible materials
EXTREMELY REACTIVE
Source: Hazardous Substances Data Bank (HSDB)
Dimethylcarbamoyl Chloride reactivity
DIMETHYLCARBAMOYL CHLORIDE is water reactive. Incompatible with strong oxidizing agents, alcohols, bases (including amines). May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291]. Gives toxic fumes of NOx and HCl when burned (USCG, 1999).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Dimethylcarbamoyl… in the storage compatibility matrix →
10 · Transport
Dimethylcarbamoyl Chloride UN number and transport classification
Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.
Dimethylcarbamoyl Chloride under UN 2262 — shipping name, class and packing group
Europe · ADR 2025, Table A
| Proper shipping name (3.1.2) | Class | Classification code | PG | Labels (column 5) |
|---|---|---|---|---|
| DIMETHYLCARBAMOYL CHLORIDE | 8 | C3 | II | |
Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 8 is “Corrosive substances” (ADR 2.1.1.1).
United States · 49 CFR 172.101 Hazardous Materials Table
| Proper shipping name (column 2) | Class or division | PG | Labels (column 6) |
|---|---|---|---|
| Dimethylcarbamoyl chloride | 8 | II | |
Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 8 is “Corrosive material” (49 CFR 173.2).
11 · Questions
Dimethylcarbamoyl Chloride — frequently asked questions
What is the CAS number of Dimethylcarbamoyl Chloride?
The CAS number of Dimethylcarbamoyl Chloride is 79-44-7. Its EC number is 201-208-6.
What is the chemical formula of Dimethylcarbamoyl Chloride?
The molecular formula of Dimethylcarbamoyl Chloride is C3H6ClNO and its molecular weight is 107.54 g/mol.
What does a Dimethylcarbamoyl Chloride label have to show?
Under CLP Annex VI the label for Dimethylcarbamoyl Chloride carries the pictograms Skull and crossbones and Health hazard and the signal word is Danger.
Is Dimethylcarbamoyl Chloride flammable?
CLP Annex VI assigns Dimethylcarbamoyl Chloride no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 68.33 °C (155 °F) (NIOSH).
Is Dimethylcarbamoyl Chloride a carcinogen?
Yes. CLP Annex VI classifies Dimethylcarbamoyl Chloride as a category 1A or 1B carcinogen and assigns it H350: may cause cancer. IARC places it in Group 2A: probably carcinogenic to humans.
What is the exposure limit for Dimethylcarbamoyl Chloride?
The US occupational exposure limit reported for Dimethylcarbamoyl Chloride is none (The National Institute for Occupational Safety and Health (NIOSH)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.
What is the boiling point of Dimethylcarbamoyl Chloride?
The boiling point reported for Dimethylcarbamoyl Chloride is 167 °C (332.6 °F) (HSDB).
What is the melting point of Dimethylcarbamoyl Chloride?
The melting point reported for Dimethylcarbamoyl Chloride is -33 °C (-27.4 °F) (HSDB).
How should Dimethylcarbamoyl Chloride be stored?
PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/ (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Dimethylcarbamoyl Chloride
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