Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Fipronil

Fipronil is a white solid.

CAS 120068-37-3 C12H4Cl2F6N4OS 437.1 g/mol Danger

01 · Identification

What Fipronil is

Fipronil is a white solid. Its molecular formula is C12H4Cl2F6N4OS and its molecular weight is 437.1 g/mol. It melts at 201 °C.

Under the GHS it carries the signal word Danger.

02 · Identifiers

Fipronil identifiers and molecular data

Fipronil CAS number and EC number

CAS number120068-37-3
EC number424-610-5
Index number (CLP Annex VI)608-055-00-8

Fipronil molecular formula and molecular weight

Molecular formulaC12H4Cl2F6N4OS
Molecular weight437.1 g/mol

Other names for Fipronil

  • fipronil (ISO)
  • (±)-5-amino-1-(2,6-dichloro-α,α,α-trifluoro-para-tolyl)-4-trifluoromethylsulfinyl-pyrazole-3-carbonitrile

03 · GHS classification

Fipronil hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Fipronil pictograms and signal word

Signal wordDanger

Fipronil hazard class and category

GHS hazard classes Fipronil falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 3 H301 GHS06
Acute toxicity - dermal GHS chapter 3.1 Category 3 H311 GHS06
Acute toxicity - inhalation GHS chapter 3.1 Category 3 H331 GHS06
Specific target organ toxicity - repeated exposure GHS chapter 3.9 Category 1 H372 GHS08
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Fipronil hazard statements (H-codes)

Hazard statements assigned to Fipronil
CodeHazard statement
H331 Toxic if inhaled.
H311 Toxic in contact with skin.
H301 Toxic if swallowed.
H372 Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Fipronil. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Fipronil

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Fipronil issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Fipronil precautionary statements

CLP Annex VI assigns 14 precautionary statements to Fipronil. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Fipronil name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български фипронил (ISO) (±)-5-амино-1-(4-(α,α,α-трифлуоро-2,6-дихлоро- р -толил)-4-трифлуорометилсулфинилпиразол-3-карбонитрил
Spanish español Fipronil (ISO) (±)-5-amino-1-(2,6-dicloro--α,α,α-trifluoro- para -tolil)-4-trifluorometilsulfinil-pirazol-3-carbonitrilo
Czech čeština fipronil (ISO) (±)-5-amino-1-(2,6-dichlor-α,α,α-(trifluormethyl)fenyl]-4-[(trifluormethyl)sulfinyl]pyrazol-3-karbonitril
Danish dansk fipronil (ISO) (±)-5-amino-1-(2,6-dichlor-α,α,α-trifluor-p-tolyl)-4-trifluormethylsulfinylpyrazol-3-carbonitril
German Deutsch Fipronil (ISO) (±)-5-Amino-1-(2,6-dichlor-α,α,α-trifluor- p -tolyl)-4-trifluormethylsulfinylpyrazol-3-carbonitril
Estonian eesti fiproniil (ISO) (±)-5-amino-1-(2,6-dikloro-α,α,α-trifluoro- para -tolüül)-4-trifluorometüülsulfinüül-pürasool-3-karbonitriil
Greek ελληνικά fipronil (φιπρονίλη) (ISO) (±)-5-αμινο-1-(2,6-διχλωρο-α,α,α-τριφθορο-π-τολυλο)-4-τριφθορομεθυλοσουλφινυλοπυραζολο-3-καρβονιτρίλιο
English English fipronil (ISO) (±)-5-amino-1-(2,6-dichloro-α,α,α-trifluoro-para-tolyl)-4-trifluoromethylsulfinyl-pyrazole-3-carbonitrile
French français fipronil (ISO) (±)-5-amino-1-(2,6-dichloro-α,α,α-trifluoro-para-tolyl)-4-trifluorométhylsulfinyl-pyrazole-3-carbonitrile
Croatian hrvatski fipronil (ISO) (±)-5-amino-1-(2,6-dikloro-α,α,α-trifluor-para-tolil)-4-trifluorometilsulfinil-pirazol-3-karbonitril
Italian italiano fipronil (ISO) (±)-5-ammino-1-(2,6-dicloro-α,α,α-trifluoro-para-tolil)-4-trifluorometilsulfinil-pirazol-3-carbonitrile
Latvian latviešu fipronils (ISO) (±)-5-amino-1-(2,6-dihlor-α,α,α-trifluor- para -tolil)-4-trifluormetilsulfinilpirazol-3-karbonitrils
Lithuanian lietuvių fipronilas (ISO) (±)-5-amino-1-(2,6-dichlor-α,α,α-trifluor-para-tolil)-4-trifluormetilsulfinilpirazol-3-karbonitrilas
Hungarian magyar fipronil (ISO) (±)-5-amino-1-(2,6-diklór-α,α,α-trifluor-para-tolil)-4-trifluormetilszulfinil-pirazol-3-karbonitril
Maltese Malti fipronil (ISO) (±)-5-ammino-1-(2,6-dikloro-α,α,α-trifluworo-para-tolil)-4-trifluworometilsulfinil-pirażol-3-karbonitril
Dutch Nederlands fipronil (ISO) (±)-5-amino-1-(2,6-dichloor-α,α,α-trifluor-para-tolyl)-4-trifluormethylsulfinyl-pyrazool-3-carbonitril
Polish polski fipronil (ISO) (±)-5-amino-1-(2,6-dichloro-α,α,α-trifluoro-para-tolilo)-4-trifluorometylosulfinylo-pirazolo-3-karbonitryl
Portuguese português Fipronil (ISO) (±)-5-amino-1-(2,6-dicloro-α,α,α-trifluoro- para -tolil)-4-trifluorometilsulfinilpirazole-3-carbonitrilo
Romanian română fipronil (ISO) (±)-5-amino-1-(2,6-dicloro-α,α,α-trifluoro-para-tolil)-4-trifluorometilsulfinil-pirazol-3-carbonitril
Slovak slovenčina fipronil (ISO) 5-amino-1-[2,6-dichlór-4-(trifluórmetyl)fenyl]-4-[(trifluórmetyl)sulfinyl]-1 H -pyrazol-3-karbonitril
Slovenian slovenščina fipronil (ISO) (±)-5-amino-1-(2,6-dikloro-α,α,α-trifluoro-para-tolil)-4-trifluorometilsulfinil-pirazol-3-karbonitril
Finnish suomi fiproniili (ISO) (±)-5-amino-1-(2,6-dikloori-α,α,α-trifluori-para-tolyyli)-4-trifluorimetyylisulfinyyli-pyratsoli-3-karbonitriili
Swedish svenska fipronil (ISO) (±)-5-amino-1-(2,6-diklor-α,α,α-trifluor-para-tolyl)-4-trifluormetylsulfinyl-pyrazol-3-karbonitril

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Fipronil GHS label elements

Everything CLP Annex VI fixes for Fipronil, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS06 Skull and crossbones pictogramGHS08 Health hazard pictogramGHS09 Environment pictogram

Danger

Fipronil

  • Toxic if inhaled.
  • Toxic in contact with skin.
  • Toxic if swallowed.
  • Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Use only outdoors or in a well-ventilated area.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • IF INHALED:
  • Immediately call a POISON CENTER/doctor/
  • Get medical advice/attention if you feel unwell.
  • Rinse mouth.
  • Wash with plenty of water/
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Fipronil in the GHS label constructor →

07 · Health hazards

Fipronil health hazards and exposure limits

Fipronil hazard summary

Sold as Magforce roach killer bait containing 0.1% fipronil; This product may be irritating to the skin and eyes following prolonged contact but is not acutely toxic after ingestion or dermal exposure; Also sold as Chipco Choice Insecticide, containing 0.1% fipronil; This product may cause seizures after skin absorption, ingestion, or inhalation. A termiticide product contains 9.1% fipronil. Seizures are listed as possible effects from overexposure to this product. [MSDSonline] Causes seizures in high-dose animal studies; Technical (96.5%) fipronil is classified as moderate toxicity, and formulated products are classified as low toxicity. Formulated products may cause some skin irritation to pets, but are not absorbed through the skin; [NPIC]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Physical and chemical properties

Fipronil properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Fipronil melting point

Property Value Conditions Source
Melting point 201 °C (393.8 °F) ICSC
200.5 °C (392.9 °F) range, midpoint shown HSDB

Fipronil density

Property Value Conditions Source
Density 1.5515 g/cm³ range, midpoint shown, at 20 °C HSDB

Fipronil solubility

Property Value Conditions Source
Solubility In water, 2 mg/L HSDB
In water, 1.9 mg/L (pH 5), 2.4 mg/L (pH 9), 1.9 mg/L (distilled), all at 20 °C at 20 °C HSDB
In organic solvents (g/L at 20 °C): acetone 545.9, dichloromethane 22.3, hexane 0.028, toluene 3.0 at 20 °C HSDB

Fipronil vapor pressure

Property Value Conditions Source
Vapor pressure 2.78e-9 mmHg at 25 °C HSDB
Vapor pressure at 20 °C: negligible at 20 °C ICSC

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

Fipronil storage and handling

Fipronil safe storage

Separated from food and feedstuffs.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Fipronil storage conditions

Keep container tightly closed in a dry and well-ventilated place.

Source: Hazardous Substances Data Bank (HSDB)

Fipronil incompatible materials

Incompatible materials: Strong oxidizing agents.

Source: Hazardous Substances Data Bank (HSDB)

Planning storage for a mix of chemicals? Check Fipronil in the storage compatibility matrix →

10 · Questions

Fipronil — frequently asked questions

What is the CAS number of Fipronil?

The CAS number of Fipronil is 120068-37-3. Its EC number is 424-610-5.

What is the chemical formula of Fipronil?

The molecular formula of Fipronil is C12H4Cl2F6N4OS and its molecular weight is 437.1 g/mol.

What does a Fipronil label have to show?

Under CLP Annex VI the label for Fipronil carries the pictograms Skull and crossbones, Health hazard and Environment and the signal word is Danger.

Is Fipronil flammable?

CLP Annex VI assigns Fipronil no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is Fipronil a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Fipronil. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the melting point of Fipronil?

The melting point reported for Fipronil is 201 °C (393.8 °F) (ICSC).

How should Fipronil be stored?

Keep container tightly closed in a dry and well-ventilated place. (Hazardous Substances Data Bank (HSDB))

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