Substance profile
Isazofos
Isazofos is an amber liquid.
01 · Identification
What Isazofos is
Isazofos is an amber liquid. Its molecular formula is C9H17ClN3O3PS and its molecular weight is 313.74 g/mol. It boils at 170 °C, is miscible with water.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Isazofos identifiers and molecular data
Isazofos CAS number and EC number
Isazofos molecular formula and molecular weight
Other names for Isazofos
- isazofos (ISO)
- O-(5-chloro-1-isopropyl-1,2,4-triazol-3-yl) O,O-diethyl phosphorothioate
03 · GHS classification
Isazofos hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Isazofos pictograms and signal word
Isazofos hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 3 | H301 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 3 | H311 | GHS06 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 1 or 2 | H330 | GHS06 |
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
| Specific target organ toxicity - repeated exposure GHS chapter 3.9 | Category 2 | H373 | GHS08 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Isazofos hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H330 | Fatal if inhaled. |
| H311 | Toxic in contact with skin. |
| H301 | Toxic if swallowed. |
| H373 | May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H317 | May cause an allergic skin reaction. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Isazofos. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Isazofos
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Isazofos issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Isazofos precautionary statements
CLP Annex VI assigns 18 precautionary statements to Isazofos. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Isazofos name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | изазофос (ISO) O -(1-изопропил-5-хлоро-1,2,4-триазол-3-илов) O, O -диетилов фосфоротиоат |
| Spanish español | Isazofós (ISO) fosforotioato de O -(5-cloro-1-isopropil-1,2,4-triazol-3-ilo) y O, O -dietilo |
| Czech čeština | isazofos (ISO) O -(5-chlor-1-isopropyl-1 H -1,2,4-triazol-3-yl)- O, O -diethyl-fosforothiát |
| Danish dansk | isazofos (ISO) O- (5-chlor-1-isopropyl-1,2,4-triazol-3-yl)- O, O- diethylthiophosphat |
| German Deutsch | Isazofos (ISO) O -(5-Chlor-1-isopropyl-1,2,4-triazol-3-yl)- O, O -diethylphosphorothioat |
| Estonian eesti | isasofoss (ISO) O -(5-kloro-1-isopropüül-1,2,4-triasool-3-üül)- O , O -dietüülfosforotioaat |
| Greek ελληνικά | isazofos (ισαζωφός) (ISO) θειοφωσφορικό O -(5-χλωρο-1-ισοπροπυλο-1,2,4-τριαζολ-3-ύλιο) O, O -διαιθύλιο |
| English English | isazofos (ISO) O -(5-chloro-1-isopropyl-1,2,4-triazol-3-yl) O, O -diethyl phosphorothioate |
| French français | isazofos (ISO) phosphorothioate de O -(5-chloro-1-isopropyl-1,2,4-triazol-3-yle) et de O, O -diéthyle |
| Croatian hrvatski | izazofos (ISO) O -(5-klor-1-izopropil-1,2,4-triazol-3-il)- O, O -dietil-fosforotioat |
| Italian italiano | isazofos (ISO) tiofosfato di O -(5-cloro-1-isopropil-1,2,4-triazol-3-ile) e di O , O -dietile |
| Latvian latviešu | isazofoss (ISO) O -(5-hlor-1-izopropil-1,2,4-triazol-3-il) O, O -dietilfosfortioāts |
| Lithuanian lietuvių | isazofosas (ISO) O -(5-chlor-1-izopropil-1,2,4-triazol-3-il)- O, O -dietiltiofosfatas |
| Hungarian magyar | izazofosz (ISO) O -(5-klór-1-izopropil-1,2,4-triazol-3-il)- O, O -dietil-tiofoszfát |
| Maltese Malti | isażofos (ISO) fosforotijoat ta’ O-(5-kloro-1-isopropil-1,2,4-triażol-3-il) O, O-dietil |
| Dutch Nederlands | isazofos (ISO) O -(5-chloor-1-isopropyl-1,2,4-triazool-3-yl)- O, O -diëthylthiofosfaat |
| Polish polski | izazofos (ISO) tiofosforan O-(5-chloro-1-izopropylo-1H-1,2,4-triazol-3-ilu)-O, O-dietylu |
| Portuguese português | isazofos (ISO) tiofosfato de O -(5-cloro-1-isopropil-1,2,4-triazol-3-ilo) e de O , O -dietilo |
| Romanian română | isazofos (ISO) tiofosfat de O -(5-cloro-1-izopropil-1,2,4-triazol-3-il) și de O, O -dietil |
| Slovak slovenčina | isazofos (ISO) O, O -dietyl- O -(5-chlór-1-izopropyl-1,2,4-triazol-3-yl)-fosforotioát |
| Slovenian slovenščina | isazofos (ISO) O -(5-kloro-1-izopropil-1,2,4-triazol-3-il) O, O -dietil fosforotioat |
| Finnish suomi | isatsofossi (ISO) O -(5-kloori-1-isopropyyli-1,2,4-triatsol-3-yyli)- O , O -dietyylifosforotioaatti |
| Swedish svenska | isazofos (ISO) O -(5-klor-1-isopropyl-1,2,4-triazol-3-yl)- O, O -dietylfosfortioat |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Isazofos GHS label elements
Everything CLP Annex VI fixes for Isazofos, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Isazofos
- Fatal if inhaled.
- Toxic in contact with skin.
- Toxic if swallowed.
- May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- May cause an allergic skin reaction.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Contaminated work clothing should not be allowed out of the workplace.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF INHALED:
- Immediately call a POISON CENTER/doctor/…
- Get medical advice/attention.
- Get medical advice/attention if you feel unwell.
- Rinse mouth.
- If skin irritation or rash occurs:
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Isazofos in the GHS label constructor →
07 · Health hazards
Isazofos health hazards and exposure limits
Isazofos hazard summary
Caused inhibition of cholinesterase activity but no gross or histopathological changes observed in long term feeding studies with rats and dogs; No evidence of increase in tumor frequency in long term feeding studies with rats; Caused developmental toxicity in rats at dose levels maternally toxic; No evidence of delayed neurotoxicity in oral studies with birds; No evidence of any mutagenic effects from the California EPA (2003); Marked increase in spontaneous mutation frequency observed with Salmonella and increase in mitotic indices and chromosome aberrations seen in bone marrow cells of mice (Mutation Research in Amsterdam 1998); [HSDB] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
Isazofos properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Isazofos boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 170 °C (338 °F) | at 760 mmHg | HSDB |
Isazofos density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.22 g/cm³ | at 20 °C | HSDB |
Isazofos solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Miscible with methanol, chloroform, benzene, hexane | HSDB | |
| In water, 69 mg/l at 20 °C | at 20 °C | HSDB |
Isazofos vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.000087 mmHg | at 25 °C | HSDB |
| 0.000087 mmHg | Haz-Map |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Questions
Isazofos — frequently asked questions
What is the CAS number of Isazofos?
The CAS number of Isazofos is 42509-80-8. Its EC number is 255-863-8.
What is the chemical formula of Isazofos?
The molecular formula of Isazofos is C9H17ClN3O3PS and its molecular weight is 313.74 g/mol.
What does a Isazofos label have to show?
Under CLP Annex VI the label for Isazofos carries the pictograms Skull and crossbones, Health hazard and Environment and the signal word is Danger.
Is Isazofos flammable?
CLP Annex VI assigns Isazofos no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Isazofos a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Isazofos. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of Isazofos?
The boiling point reported for Isazofos is 170 °C (338 °F), at 760 mmHg (HSDB).
Nearby
Substances next to Isazofos
Keep going: substances starting with I, or search the whole database by name, CAS number, pictogram or signal word.