Substance profile
N-Nitrosodimethylamine
N-Nitrosodimethylamine is a yellow, oily liquid with a faint, characteristic odor.
01 · Identification
What N-Nitrosodimethylamine is
N-Nitrosodimethylamine is a yellow, oily liquid with a faint, characteristic odor. Its molecular formula is C2H6N2O and its molecular weight is 74.08 g/mol. It boils at 152 °C, melts at 25 °C.
Under the GHS it carries the signal word Danger. It is classed as hazardous Air Pollutants (HAPs).
02 · Identifiers
N-Nitrosodimethylamine identifiers and molecular data
N-Nitrosodimethylamine CAS number and EC number
N-Nitrosodimethylamine molecular formula and molecular weight
Other names for N-Nitrosodimethylamine
- dimethylnitrosoamine
03 · GHS classification
N-Nitrosodimethylamine hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
N-Nitrosodimethylamine pictograms and signal word
N-Nitrosodimethylamine hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 3 | H301 | GHS06 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 1 or 2 | H330 | GHS06 |
| Carcinogenicity GHS chapter 3.6 | Category 1A or 1B | H350 | GHS08 |
| Specific target organ toxicity - repeated exposure GHS chapter 3.9 | Category 1 | H372 | GHS08 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 2 | H411 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
N-Nitrosodimethylamine hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H350 | May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H330 | Fatal if inhaled. |
| H301 | Toxic if swallowed. |
| H372 | Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H411 | Toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to N-Nitrosodimethylamine. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for N-Nitrosodimethylamine
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of N-Nitrosodimethylamine issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
N-Nitrosodimethylamine precautionary statements
CLP Annex VI assigns 15 precautionary statements to N-Nitrosodimethylamine. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
N-Nitrosodimethylamine name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | диметилнитрозоамин N -нитрозодиметиламин |
| Spanish español | Dimetilnitrosoamina N -nitrosodimetilamina |
| Czech čeština | dimethylnitrosoamin N -nitrosodimethylamin |
| Danish dansk | dimethylnitrosoamin N- nitrosodimethylamin |
| German Deutsch | Dimethylnitrosamin N -Nitrosodimethylamin |
| Estonian eesti | dimetüülnitrosoamiin N -nitrosodimetüülamiin |
| Greek ελληνικά | διμεθυλονιτροζαμίνη N -νιτρωδοδιμεθυλαμίνη |
| English English | dimethylnitrosoamine N -nitrosodimethylamine |
| French français | diméthylnitrosoamine N -nitrosodiméthylamine |
| Croatian hrvatski | dimetilnitrozoamin N -nitrozodimetilamin |
| Italian italiano | dimetilnitrosoamina N- nitrosodimetilamina |
| Latvian latviešu | dimetilnitrozoamīns N -nitrozodimetilamīns |
| Lithuanian lietuvių | dimetilnitrozaminas N -nitrozodimetilaminas |
| Hungarian magyar | dimetilnitrozoamin N -nitrozodimetilamin |
| Maltese Malti | dimetilnitrosoammina N -nitrosodimetilammina |
| Dutch Nederlands | dimethylnitrosoamine N -nitrosodimethylamine |
| Polish polski | dimetylonitrozoamina N -nitrozodimetyloamina |
| Portuguese português | dimetilnitrosoamina N -nitrosodimetilamina |
| Romanian română | dimetilnitrozoamină N -nitrozodimetilamină |
| Slovak slovenčina | dimetyl(nitrózo)amín N -nitrózodimetylamín |
| Slovenian slovenščina | dimetilnitrozoamin N -nitrozodimetilamin |
| Finnish suomi | dimetyylinitrosamiini N -nitrosodimetyyliamiini |
| Swedish svenska | dimetylnitrosoamin N -nitrosodimetylamin |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
N-Nitrosodimethylamine GHS label elements
Everything CLP Annex VI fixes for N-Nitrosodimethylamine, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
N-Nitrosodimethylamine
- May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Fatal if inhaled.
- Toxic if swallowed.
- Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Toxic to aquatic life with long lasting effects.
- Obtain special instructions before use.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF INHALED:
- IF exposed or concerned:
- Immediately call a POISON CENTER/doctor/…
- Get medical advice/attention.
- Get medical advice/attention if you feel unwell.
- Rinse mouth.
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open N-Nitrosodimethylamine in the GHS label constructor →
07 · Health hazards
N-Nitrosodimethylamine health hazards and exposure limits
N-Nitrosodimethylamine hazard summary
n-Nitrosodimethylamine is produced by industry only in small amounts for research. At room temperature, it is a yellow liquid with no distinct odor. It was used to make rocket fuel, but this use was stopped after unusually high levels of this chemical were found in air, water, and soil samples collected near a rocket fuel manufacturing plant. It is used in some cosmetic and toiletry products and in cleansers.n-Nitrosodimethylamine is unintentionally formed during various manufacturing processes and in air, water, and soil from reactions involving other chemicals called alkylamines. It is also found in some foods and may be formed in the body.
Source: Agency for Toxic Substances and Disease Registry (ATSDR)
N-Nitrosodimethylamine carcinogenicity classification
No data are available in humans. Sufficient evidence of carcinogenicity in animals. OVERALL EVALUATION: Group 2A: The agent is probably carcinogenic to humans.
Source: Hazardous Substances Data Bank (HSDB)
... Identified as an occupational carcinogen.
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
N-Nitrosodimethylamine occupational exposure limits
| Limit | Value | Source |
|---|---|---|
| PEL | [1910.1016] See Appendix B | The National Institute for Occupational Safety and Health (NIOSH) |
| REL | Ca See Appendix A | The National Institute for Occupational Safety and Health (NIOSH) |
| IDLH | A potential occupational carcinogen. (NIOSH, 2024) | CAMEO Chemicals |
| IDLH | NIOSH considers N-nitrosodimethylamine to be a potential occupational carcinogen. | Hazardous Substances Data Bank (HSDB) |
| IDLH | Ca [N.D.] | The National Institute for Occupational Safety and Health (NIOSH) |
These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.
08 · Physical and chemical properties
N-Nitrosodimethylamine properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
N-Nitrosodimethylamine boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 152 °C (305.6 °F) | HSDB | |
| 152.22 °C (306 °F) | NIOSH | ||
| 151 °C (303.8 °F) | ICSC |
N-Nitrosodimethylamine melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 25 °C (77 °F) | below this value | HMDB |
N-Nitrosodimethylamine density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.005 g/cm³ | NIOSH | |
| 1.0048 g/cm³ | at 20 °C | HSDB |
N-Nitrosodimethylamine solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Infinitely soluble in water at 23-25 °C | HSDB | |
| Soluble in all common organic solvents and in lipids | HSDB | ||
| Very soluble in water, alcohol, ether | HSDB |
N-Nitrosodimethylamine vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 3 mmHg | NIOSH | |
| 2.7 mmHg | at 20 °C | HSDB | |
| 2.7002 mmHg | at 20 °C | ICSC |
N-Nitrosodimethylamine flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 61.11 °C (142 °F) | CAMEO | |
| 61 °C (141.8 °F) | ICSC |
N-Nitrosodimethylamine lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | Combustible Liquid | NIOSH |
N-Nitrosodimethylamine vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 2.56 (air = 1) | HSDB |
N-Nitrosodimethylamine odor threshold
| Property | Value | Conditions | Source |
|---|---|---|---|
| Odor threshold | Odor Threshold Low: 0.0079 [ppm] | Haz-Map | |
| Odor Threshold High: 0.01 [ppm] | Haz-Map | ||
| Odor threshold from AIHA | Haz-Map |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
N-Nitrosodimethylamine fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
N-Nitrosodimethylamine fire potential
Combustible
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
N-Nitrosodimethylamine storage and handling
N-Nitrosodimethylamine safe storage
Separated from strong oxidants and food and feedstuffs. Cool. Keep in the dark. Well closed.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
N-Nitrosodimethylamine storage conditions
ALL BOTTLES OF N-NITROSODIETHYLAMINE SHOULD BE STORED & TRANSPORTED WITHIN UNBREAKABLE OUTER CONTAINER; STORAGE SHOULD BE IN VENTILATED STORAGE CABINET (OR IN HOOD). /N-NITROSODIETHYLAMINE, ALSO APPLICABLE TO OTHER DIALKYLNITROSAMINES/
Source: Hazardous Substances Data Bank (HSDB)
N-Nitrosodimethylamine incompatible materials
Oxidants, especially peracids. Sensitive to UV light.
Source: Hazardous Substances Data Bank (HSDB)
N-Nitrosodimethylamine reactivity
N-NITROSODIMETHYLAMINE is sensitive to exposure to light, especially ultraviolet light. Is stable at room temperature for more than 14 days in aqueous solution at neutral and alkaline pH in the absence of light. Slightly less stable at strongly acid pH at room temperature. Incompatible with strong oxidizing agents. Also incompatible with strong bases. Can be reduced by reducing agents. Incompatible with hydrogen bromide in acetic acid. Also photochemically reactive. (NTP, 1992)
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check N-Nitrosodimethylamine in the storage compatibility matrix →
11 · Questions
N-Nitrosodimethylamine — frequently asked questions
What is the CAS number of N-Nitrosodimethylamine?
The CAS number of N-Nitrosodimethylamine is 62-75-9. Its EC number is 200-549-8.
What is the chemical formula of N-Nitrosodimethylamine?
The molecular formula of N-Nitrosodimethylamine is C2H6N2O and its molecular weight is 74.08 g/mol.
What does a N-Nitrosodimethylamine label have to show?
Under CLP Annex VI the label for N-Nitrosodimethylamine carries the pictograms Skull and crossbones, Health hazard and Environment and the signal word is Danger.
Is N-Nitrosodimethylamine flammable?
CLP Annex VI assigns N-Nitrosodimethylamine no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 61.11 °C (142 °F) (CAMEO).
Is N-Nitrosodimethylamine a carcinogen?
Yes. CLP Annex VI classifies N-Nitrosodimethylamine as a category 1A or 1B carcinogen and assigns it H350: may cause cancer. IARC places it in Group 2A: probably carcinogenic to humans.
What is the exposure limit for N-Nitrosodimethylamine?
The US occupational exposure limit reported for N-Nitrosodimethylamine is [1910.1016] See Appendix B (The National Institute for Occupational Safety and Health (NIOSH)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.
What is the boiling point of N-Nitrosodimethylamine?
The boiling point reported for N-Nitrosodimethylamine is 152 °C (305.6 °F) (HSDB).
What is the melting point of N-Nitrosodimethylamine?
The melting point reported for N-Nitrosodimethylamine is 25 °C (77 °F), below this value (HMDB).
How should N-Nitrosodimethylamine be stored?
ALL BOTTLES OF N-NITROSODIETHYLAMINE SHOULD BE STORED & TRANSPORTED WITHIN UNBREAKABLE OUTER CONTAINER; STORAGE SHOULD BE IN VENTILATED STORAGE CABINET (OR IN HOOD). /N-NITROSODIETHYLAMINE, ALSO APPLICABLE TO OTHER DIALKYLNITROSAMINES/ (Hazardous Substances Data Bank (HSDB))
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