Substance profile
Piperonyl Butoxide
Piperonyl Butoxide is a colorless liquid and is odorless.
01 · Identification
What Piperonyl Butoxide is
Piperonyl Butoxide is a colorless liquid and is odorless. Its molecular formula is C19H30O5 and its molecular weight is 338.4 g/mol.
Under the GHS it carries the signal word Warning.
02 · Identifiers
Piperonyl Butoxide identifiers and molecular data
Piperonyl Butoxide CAS number and EC number
Piperonyl Butoxide molecular formula and molecular weight
Other names for Piperonyl Butoxide
- piperonyl butoxide (ISO)
- 2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether
03 · GHS classification
Piperonyl Butoxide hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Piperonyl Butoxide pictograms and signal word
Piperonyl Butoxide hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 2A | H319 | GHS07 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 3 | H335 | GHS07 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Piperonyl Butoxide hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H335 | May cause respiratory irritation. |
| H319 | Causes serious eye irritation. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
Piperonyl Butoxide supplemental EU statements (EUH)
| Code | Statement |
|---|---|
| EUH066 | Repeated exposure may cause skin dryness or cracking. |
This page lists only the codes assigned to Piperonyl Butoxide. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Piperonyl Butoxide
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Piperonyl Butoxide issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Piperonyl Butoxide precautionary statements
CLP Annex VI assigns 9 precautionary statements to Piperonyl Butoxide. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Piperonyl Butoxide name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | пиперонил бутоксид (ISO) 2-(2-бутоксиетокси)етил-6-пропилпиперонилов етер |
| Spanish español | Butóxido de piperonilo (ISO) éter de 2-(2-butoxietoxi)etil y 6-propilpiperonilo |
| Czech čeština | piperonylbutoxid (ISO) 5-{[2-(2-butoxyethoxy)ethoxy]methyl}-6-propyl-1,3-benzodioxol |
| Danish dansk | piperonylbutoxid (ISO) 2-(2-butoxyethoxy)ethyl-6-propylpiperonylether |
| German Deutsch | Piperonylbutoxid (ISO) 2-(2-Butoxyethoxy)ethyl-6-propylpiperonylether |
| Estonian eesti | piperonüülbutoksiid (ISO) 2-(2-butoksüetoksü)etüül-6-propüülpiperonüüleeter |
| Greek ελληνικά | piperonyl butoxide (πιπερονυλοβουτοξείδιο) (ISO) 2-(2-βουτοξυαιθοξυ)αιθυλ-6-προπυλοπιπερονυλικός αιθέρας |
| English English | piperonyl butoxide (ISO) 2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether |
| French français | butoxyde de pipéronyle (ISO) oxyde de 2-(2-butoxyéthoxy)éthyle et de 6-propylpipéronyle |
| Croatian hrvatski | piperonil butoksid (ISO) 2-(2-butoksietoksi)etil 6-propilpiperonil eter |
| Italian italiano | piperonilbutossido (ISO) 2-(2-butossietossi)etil 6-propilpiperoniletere |
| Latvian latviešu | piperonila butoksīds (ISO) 2-(2-butoksietoksi)etil-6-propilpiperonilēteris |
| Lithuanian lietuvių | piperonilbutoksidas (ISO) 2-(2-butoksietoksi)etil 6-propilpiperonileteris |
| Hungarian magyar | piperonil-butoxid (ISO) 2-(2-butoxietoxi)etil 6-propilpiperonil-éter |
| Maltese Malti | butossidu tal-piperonil (ISO) etere ta’ 2-(2-butossietossi)etil 6-propilpiperonil |
| Dutch Nederlands | piperonylbutoxide (ISO) 2-(2-butoxyethoxy)ethyl-6-propylpiperonylether |
| Polish polski | butotlenek piperonylu (ISO) eter 2-(2-butoksyetoksy)etylo-6-propylopiperonylowy |
| Portuguese português | butóxido de piperonilo (ISO) éter 2-(2-butoxietoxi)etil-6-propilpiperonílico |
| Romanian română | piperonil butoxid (ISO) 2-(2-butoxietoxi)etil 6-propilpiperonil eter |
| Slovak slovenčina | piperonil butoxid (ISO) 2-(2-butoxietoxi)etil 6-propilpiperonil eter |
| Slovenian slovenščina | piperonil butoksid (ISO) 2-(2-butoksietoksi)etil 6-propilpiperonil eter |
| Finnish suomi | piperonyylibutoksidi (ISO) 2-(2-butoksietoksi)etyyli-6-propyylipiperonyylieetteri |
| Swedish svenska | piperonylbutoxid (ISO) 2-(2-butoxietoxi)etyl-6-propylpiperonyleter |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Piperonyl Butoxide GHS label elements
Everything CLP Annex VI fixes for Piperonyl Butoxide, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
Piperonyl Butoxide
- May cause respiratory irritation.
- Causes serious eye irritation.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Repeated exposure may cause skin dryness or cracking.
- Wash … thoroughly after handling.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF IN EYES:
- Get medical advice/attention.
- If eye irritation persists:
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Piperonyl Butoxide in the GHS label constructor →
07 · Health hazards
Piperonyl Butoxide health hazards and exposure limits
Piperonyl Butoxide hazard summary
No listed effects of short-term or long-term exposure; [ICSC] Skin absorption is limited, and mammalian toxicity is low; [EPA Pesticides, p. 191]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Piperonyl Butoxide carcinogenicity classification
Studied by the US National Toxicology Program: TR-120: Bioassay of Piperonyl Butoxide for Possible Carcinogenicity (CASRN 51-03-6) (1979 )
PBO is classified as a Group C-possible human carcinogen with no cancer quantification required for PBO risk assessments.
Source: Hazardous Substances Data Bank (HSDB)
No data are available in humans. Inadequate evidence of carcinogenicity in animals. OVERALL EVALUATION: Group 3: The agent is not classifiable as to its carcinogenicity to humans.
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
Piperonyl Butoxide properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Piperonyl Butoxide boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 180 °C (356 °F) | at 1 mmHg (reduced pressure), Technical | HSDB |
| 180 °C (356 °F) | at 1 mmHg (reduced pressure) | CAMEO | |
| 180 °C (356 °F) | at 0.97508 mmHg (reduced pressure) | ICSC |
Piperonyl Butoxide density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.1 g/cm³ | ICSC | |
| 1.06 g/cm³ | at 20 °C | HSDB |
Piperonyl Butoxide solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Miscible with methanol, ethanol, benzene, Freons, Geons, petroleum oils, and other organic solvents | HSDB | |
| Solubility in water: none | ICSC | ||
| In water, 14.3 mg/L at 25 °C | at 25 °C | HSDB |
Piperonyl Butoxide vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 2.6e-7 mmHg | Haz-Map |
Piperonyl Butoxide flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 171.11 °C (340 °F) | HSDB | |
| 171 °C (339.8 °F) | ICSC |
Piperonyl Butoxide corrosivity
| Property | Value | Conditions | Source |
|---|---|---|---|
| Corrosivity | NONCORROSIVE | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
Piperonyl Butoxide fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Piperonyl Butoxide fire potential
Combustible when exposed to heat or flame; can react with oxidizing materials.
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
Piperonyl Butoxide storage and handling
Piperonyl Butoxide safe storage
Well closed.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Piperonyl Butoxide storage conditions
Safe Storage of Pesticides. Always store pesticides in their original containers, complete with labels that list ingredients, directions for use, and first aid steps in case of accidental poisoning. Never store pesticides in cabinets with or near food, animal feed, or medical supplies. Do not store pesticides in places where flooding is possible or in places where they might spill or leak into wells, drains, ground water, or surface water.
Source: Hazardous Substances Data Bank (HSDB)
Piperonyl Butoxide incompatible materials
... Can react with oxidizing materials.
Source: Hazardous Substances Data Bank (HSDB)
Piperonyl Butoxide reactivity
PIPERONYL BUTOXIDE can react with oxidizing materials. (NTP, 1992)
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Piperonyl Butoxide in the storage compatibility matrix →
11 · Questions
Piperonyl Butoxide — frequently asked questions
What is the CAS number of Piperonyl Butoxide?
The CAS number of Piperonyl Butoxide is 51-03-6. Its EC number is 200-076-7.
What is the chemical formula of Piperonyl Butoxide?
The molecular formula of Piperonyl Butoxide is C19H30O5 and its molecular weight is 338.4 g/mol.
What does a Piperonyl Butoxide label have to show?
Under CLP Annex VI the label for Piperonyl Butoxide carries the pictograms Exclamation mark and Environment and the signal word is Warning.
Is Piperonyl Butoxide flammable?
CLP Annex VI assigns Piperonyl Butoxide no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 171.11 °C (340 °F) (HSDB).
Is Piperonyl Butoxide a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Piperonyl Butoxide. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health. IARC places it in Group 3: not classifiable as to its carcinogenicity to humans.
What is the boiling point of Piperonyl Butoxide?
The boiling point reported for Piperonyl Butoxide is 180 °C (356 °F), at 1 mmHg (reduced pressure), Technical (HSDB).
How should Piperonyl Butoxide be stored?
Safe Storage of Pesticides. Always store pesticides in their original containers, complete with labels that list ingredients, directions for use, and first aid steps in case of accidental poisoning. Never store pesticides in cabinets with or near food, animal feed, or medical supplies. Do not store pesticides in places where flooding is possible or in places where they might spill or leak into wells, drains, ground water, or surface water. (Hazardous Substances Data Bank (HSDB))
Nearby
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