Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

Build a label

Substance profile

Trichloroacetonitrile

Trichloroacetonitrile is a colorless liquid.

CAS 545-06-2 C2Cl3N 144.38 g/mol Danger

01 · Identification

What Trichloroacetonitrile is

Trichloroacetonitrile is a colorless liquid. Its molecular formula is C2Cl3N and its molecular weight is 144.38 g/mol. It boils at 85.7 °C, melts at -42 °C, is practically insoluble in water.

Under the GHS it carries the signal word Danger.

02 · Identifiers

Trichloroacetonitrile identifiers and molecular data

Trichloroacetonitrile CAS number and EC number

CAS number545-06-2
EC number208-885-7
Index number (CLP Annex VI)608-002-00-9

Trichloroacetonitrile molecular formula and molecular weight

Molecular formulaC2Cl3N
Molecular weight144.38 g/mol

03 · GHS classification

Trichloroacetonitrile hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Trichloroacetonitrile pictograms and signal word

Signal wordDanger

Trichloroacetonitrile hazard class and category

GHS hazard classes Trichloroacetonitrile falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 3 H301 GHS06
Acute toxicity - dermal GHS chapter 3.1 Category 3 H311 GHS06
Acute toxicity - inhalation GHS chapter 3.1 Category 3 H331 GHS06
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 2 H411 GHS09

Trichloroacetonitrile hazard statements (H-codes)

Hazard statements assigned to Trichloroacetonitrile
CodeHazard statement
H331 Toxic if inhaled.
H311 Toxic in contact with skin.
H301 Toxic if swallowed.
H411 Toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Trichloroacetonitrile. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Trichloroacetonitrile

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Trichloroacetonitrile issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Trichloroacetonitrile precautionary statements

CLP Annex VI assigns 13 precautionary statements to Trichloroacetonitrile. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Trichloroacetonitrile name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български трихлороацетонитрил
Spanish español Tricloroacetonitrilo
Czech čeština trichloracetonitril
Danish dansk trichloracetonitril
German Deutsch Trichloracetonitril
Estonian eesti trikloroatsetonitriil
Greek ελληνικά τριχλωροακετονιτρίλιο
English English trichloroacetonitrile
French français trichloroacétonitrile
Croatian hrvatski trikloracetonitril
Italian italiano tricloroacetonitrile
Latvian latviešu trihloracetonitrils
Lithuanian lietuvių trichloracetonitrilas
Hungarian magyar triklóracetonitril
Maltese Malti trikloroaċetonitril
Dutch Nederlands trichlooracetonitril
Polish polski trichloroacetonitryl nitryl kwasu trichlorooctowego
Portuguese português tricloroacetonitrilo
Romanian română tricloroacetonitril
Slovak slovenčina trichlóracetonitril
Slovenian slovenščina trikloroacetonitril
Finnish suomi triklooriasetonitriili
Swedish svenska trikloracetonitril

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Trichloroacetonitrile GHS label elements

Everything CLP Annex VI fixes for Trichloroacetonitrile, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS06 Skull and crossbones pictogramGHS09 Environment pictogram

Danger

Trichloroacetonitrile

  • Toxic if inhaled.
  • Toxic in contact with skin.
  • Toxic if swallowed.
  • Toxic to aquatic life with long lasting effects.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Use only outdoors or in a well-ventilated area.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • IF INHALED:
  • Immediately call a POISON CENTER/doctor/
  • Rinse mouth.
  • Wash with plenty of water/
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Trichloroacetonitrile in the GHS label constructor →

07 · Health hazards

Trichloroacetonitrile health hazards and exposure limits

Trichloroacetonitrile hazard summary

Toxic by inhalation, ingestion, and skin absorption; [eChemPortal: ESIS] A strong skin, eye, and respiratory tract irritant; A lachrymator; [CAMEO] An irritant; Can be absorbed through skin; Effects in high-dose animal studies include lacrimation; [MSDSonline]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Trichloroacetonitrile carcinogenicity classification

IARC classification Group 3 — Not classifiable as to its carcinogenicity to humans
IARC monographs Volume 52: (1991) Chlorinated Drinking-water; Chlorination By-products; Some Other Halogenated Compounds; Cobalt and Cobalt Compounds; Volume 71: (1999) Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide (Part 1, Part 2, Part 3)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

08 · Physical and chemical properties

Trichloroacetonitrile properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Trichloroacetonitrile boiling point

Property Value Conditions Source
Boiling point 85.7 °C (186.3 °F) HSDB
83.33 °C (182 °F) range, midpoint shown, at 760 mmHg CAMEO

Trichloroacetonitrile melting point

Property Value Conditions Source
Melting point -42 °C (-43.6 °F) HSDB
-42.22 °C (-44 °F) CAMEO

Trichloroacetonitrile density

Property Value Conditions Source
Density 1.4403 g/cm³ at 25 °C HSDB

Trichloroacetonitrile solubility

Property Value Conditions Source
Solubility Insoluble in water HSDB
less than 1 mg/mL at 70.7 °F (NTP, 1992) at 21.5 °C CAMEO

Trichloroacetonitrile vapor pressure

Property Value Conditions Source
Vapor pressure 74.1 mmHg at 25 °C HSDB
74.1 mmHg Haz-Map

Trichloroacetonitrile flash point

Property Value Conditions Source
Flash point 195 °C (383 °F) closed cup HSDB
74.17 °C (165.5 °F) CAMEO

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

Trichloroacetonitrile storage and handling

Trichloroacetonitrile storage conditions

Keep tightly closed.

Source: Hazardous Substances Data Bank (HSDB)

Trichloroacetonitrile reactivity

May be sensitive to light and heat. This compound may react with water, steam, acid or acid fumes. It may hydrolyze under acidic or alkaline conditions. (NTP, 1992). The reaction of benzene and trichloroacetonitrile evolves toxic chloroform and HCl gases. (Hagedorn, F., H.-P. Gelbke, and Federal Republic of Germany. 2002. Nitriles. In Ullmann's Encyclopedia of Industrial Chemistry. Wiley-VCH Verlag GmbH & Co. KGaA.).

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Trichloroacetonitrile in the storage compatibility matrix →

10 · Questions

Trichloroacetonitrile — frequently asked questions

What is the CAS number of Trichloroacetonitrile?

The CAS number of Trichloroacetonitrile is 545-06-2. Its EC number is 208-885-7.

What is the chemical formula of Trichloroacetonitrile?

The molecular formula of Trichloroacetonitrile is C2Cl3N and its molecular weight is 144.38 g/mol.

What does a Trichloroacetonitrile label have to show?

Under CLP Annex VI the label for Trichloroacetonitrile carries the pictograms Skull and crossbones and Environment and the signal word is Danger.

Is Trichloroacetonitrile flammable?

CLP Annex VI assigns Trichloroacetonitrile no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 195 °C (383 °F), closed cup (HSDB).

Is Trichloroacetonitrile a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Trichloroacetonitrile. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health. IARC places it in Group 3: not classifiable as to its carcinogenicity to humans.

What is the boiling point of Trichloroacetonitrile?

The boiling point reported for Trichloroacetonitrile is 85.7 °C (186.3 °F) (HSDB).

What is the melting point of Trichloroacetonitrile?

The melting point reported for Trichloroacetonitrile is -42 °C (-43.6 °F) (HSDB).

How should Trichloroacetonitrile be stored?

Keep tightly closed. (Hazardous Substances Data Bank (HSDB))

Nearby

Substances next to Trichloroacetonitrile

Keep going: substances starting with T, or search the whole database by name, CAS number, pictogram or signal word.

Get the free GHS / CLP / OSHA deadline calendar

Verified 2026–2029 compliance dates in one PDF — plus alerts when the rules change.