Substance profile
Bisphenol A
Bisphenol A is crystallizes as prisms from dil acetic acid and as needles from water with a mild phenolic odor.
01 · Identification
What Bisphenol A is
Bisphenol A is crystallizes as prisms from dil acetic acid and as needles from water with a mild phenolic odor. Its molecular formula is C15H16O2 and its molecular weight is 228.29 g/mol. It boils at 361 °C, melts at 160 °C.
Under the GHS it carries the signal word Danger. It is classed as flammable agents - 2nd degree.
02 · Identifiers
Bisphenol A identifiers and molecular data
Bisphenol A CAS number and EC number
Bisphenol A molecular formula and molecular weight
Other names for Bisphenol A
- BPA
- Beta,Beta'-Bis(P-Hydroxyphenyl)Propane
- Beta-Di-P-Hydroxyphenylpropane
- Bis(4-Hydroxyphenyl) Dimethylmethane
- Bis(4-Hydroxyphenyl)Propane
- 2,2'-Bis(4-Hydroxyphenyl)Propane
- 2,2-Bis(4-Hydroxyphenyl)Propane
- Bis(P-Hydroxyphenyl)Propane
- 2,2-Bis(P-Hydroxyphenyl)Propane
- Bisphenol
- 4,4'-Bisphenol A
- Bpa 154
- Bpa 157
- 4,4'-isopropylidenediphenol
03 · GHS classification
Bisphenol A hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Bisphenol A pictograms and signal word
Bisphenol A hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 1 | H318 | GHS05 |
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 3 | H335 | GHS07 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Bisphenol A hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H360F | May damage fertility. |
| H335 | May cause respiratory irritation. |
| H318 | Causes serious eye damage. |
| H317 | May cause an allergic skin reaction. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Bisphenol A. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Bisphenol A
Our own Bisphenol A safety data sheet walks through all sixteen sections of the published data. What it is not is the document an inspector asks for: an SDS is issued for a product by its supplier, so the sheet covering the grade actually standing in your store exists only in that supplier’s version. Collecting those and keeping them current as suppliers revise them is a separate job.
04 · Precautionary statements
Bisphenol A precautionary statements
CLP Annex VI assigns 11 precautionary statements to Bisphenol A. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Bisphenol A name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 4,4′-изопропилидендифенол бисфенол A |
| Spanish español | 4,4′-Isopropilidendifenol bisfenol A |
| Czech čeština | 4,4′-isopropylidendifenol bisfenol A |
| Danish dansk | 4,4′-isopropylidendiphenol bisphenol A |
| German Deutsch | 4,4’-Isopropylidendiphenol Bisphenol A |
| Estonian eesti | 4,4′-isopropülideendifenool bisfenool A |
| Greek ελληνικά | 4,4′-ισοπροπυλιδενοδιφαινόλη δισφαινόλη Α |
| English English | 4,4'-isopropylidenediphenol bisphenol A |
| French français | 4,4’-isopropylidènediphénol bisphénol A |
| Croatian hrvatski | 4,4’-izopropilidendifenol bisfenol A |
| Italian italiano | 4,4′-isopropilidendifenolo bisfenolo A |
| Latvian latviešu | 4,4′-izopropilidēndifenols bisfenols A |
| Lithuanian lietuvių | 4,4’-izopropilidendifenolis bisfenolis A |
| Hungarian magyar | 4,4′-izopropilidén-difenol biszfenol A |
| Maltese Malti | 4,4’-isopropilidendifenol bisfenol A |
| Dutch Nederlands | 4,4'-isopropylideendifenol bisfenol A |
| Polish polski | 4,4′-izopropylidenodifenol bisfenol A |
| Portuguese português | 4,4’-isopropilidenodifenol bisfenol A |
| Romanian română | 4,4’-izopropilidendifenol bisfenol A |
| Slovak slovenčina | 4,4’-izopropilidendifenol bisfenol A |
| Slovenian slovenščina | 4,4’-izopropilidendifenol bisfenol A |
| Finnish suomi | 4,4′-isopropylideenidifenoli bisfenoli A |
| Swedish svenska | 4,4’-isopropylidendifenol bisfenol A |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Bisphenol A GHS label elements
Everything CLP Annex VI fixes for Bisphenol A, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Bisphenol A
- May damage fertility.
- May cause respiratory irritation.
- Causes serious eye damage.
- May cause an allergic skin reaction.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Contaminated work clothing should not be allowed out of the workplace.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF IN EYES:
- Immediately call a POISON CENTER/doctor/…
- Get medical advice/attention.
- If skin irritation or rash occurs:
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Bisphenol A in the GHS label constructor →
07 · Health hazards
Bisphenol A health hazards and exposure limits
Bisphenol A hazard summary
A skin, eye, and respiratory tract irritant; Repeated or prolonged contact may cause skin sensitization. [ICSC] Reports of sensitization are rare; A possible sensitizer in vinyl gloves; [Kanerva, p. 1759] Danger of photo-contact sensitization; [MAK]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Bisphenol A carcinogenicity classification
Under the conditions of this bioassay, there was no convincing evidence that bisphenol A was carcinogenic for F344 rats or B6C3F1 mice of either sex.
Source: US National Toxicology Program · TR-215: Carcinogenesis Bioassay of Bisphenol A (CASRN 80-05-7) in F344 Rats and B6C3F1 Mice (Feed Study) (1982 )
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
Bisphenol A properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Bisphenol A boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 360.5 °C (680.9 °F) | at 760 mmHg | HSDB |
| 220 °C (428 °F) | OSHA | ||
| 220 °C (428 °F) | at 4 mmHg (reduced pressure) | HSDB |
Bisphenol A melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 160 °C (320 °F) | HSDB | |
| 153 °C (307.4 °F) | DOE PAC | ||
| 152.5 °C (306.5 °F) | range, midpoint shown | HSDB |
Bisphenol A density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.195 g/cm³ | at 25 °C | HSDB |
| 1.2 g/cm³ | at 25 °C | ICSC |
Bisphenol A solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Insoluble in water | HSDB | |
| In water, 300 mg/L at 25 °C | at 25 °C | HSDB | |
| In water solubility, 120 mg/L at 25 °C | at 25 °C | HSDB |
Bisphenol A vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 4e-8 mmHg | at 25 °C | HSDB |
| 0.2 mmHg | at 170 °C | CAMEO |
Bisphenol A flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 227 °C (440.6 °F) | closed cup | HSDB |
| 79.44 °C (175 °F) | CAMEO | ||
| 227 °C (440.6 °F) | ICSC |
Bisphenol A autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 540 °C (1004 °F) | range, midpoint shown | HSDB |
Bisphenol A lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | Finely dispersed particles form explosive mixtures in air. | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
Bisphenol A fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Bisphenol A fire potential
Bisphenol A is a combustible solid.
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
Bisphenol A storage and handling
Bisphenol A reactive group
CAMEO Chemicals places Bisphenol A in the reactive group Phenols and Cresols. Compatibility with other chemicals is worked out from the group, not from the individual substance — which is why two substances you have never seen react can still be flagged as a pair that must be separated.
A reactive group is a CAMEO Chemicals (US NOAA) grouping, not a GHS hazard class: it has no code, no category and no legal force. It is what the storage compatibility matrix on this site computes from.
Bisphenol A safe storage
Separated from acid anhydrides, acid chlorides, strong oxidants, strong bases and food and feedstuffs. Store in an area without drain or sewer access.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Bisphenol A storage conditions
Keep container tightly closed in a dry and well-ventilated place.
Source: Hazardous Substances Data Bank (HSDB)
Bisphenol A incompatible materials
Incompatible materials: Strong oxidizing agents.
Source: Hazardous Substances Data Bank (HSDB)
Bisphenol A reactivity
4,4'-ISOPROPYLIDENEDIPHENOL is incompatible with strong oxidizers. It is also incompatible with strong bases, acid chlorides and acid anhydrides. (NTP, 1992)
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Bisphenol A in the storage compatibility matrix →
11 · Questions
Bisphenol A — frequently asked questions
What is the CAS number of Bisphenol A?
The CAS number of Bisphenol A is 80-05-7. Its EC number is 201-245-8.
What is the chemical formula of Bisphenol A?
The molecular formula of Bisphenol A is C15H16O2 and its molecular weight is 228.29 g/mol.
What does a Bisphenol A label have to show?
Under CLP Annex VI the label for Bisphenol A carries the pictograms Health hazard, Exclamation mark, Corrosion and Environment and the signal word is Danger.
Is Bisphenol A flammable?
CLP Annex VI assigns Bisphenol A no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 227 °C (440.6 °F), closed cup (HSDB).
Is Bisphenol A a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Bisphenol A. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of Bisphenol A?
The boiling point reported for Bisphenol A is 360.5 °C (680.9 °F), at 760 mmHg (HSDB).
What is the melting point of Bisphenol A?
The melting point reported for Bisphenol A is 160 °C (320 °F) (HSDB).
How should Bisphenol A be stored?
Keep container tightly closed in a dry and well-ventilated place. (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Bisphenol A
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