Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

Build a label

Substance profile

Diphenylguanidine

Diphenylguanidine is monoclinic needles (crystalized from alcohol and toluene) with a slight odor.

CAS 102-06-7 C13H13N3 211.26 g/mol Warning

01 · Identification

What Diphenylguanidine is

Diphenylguanidine is monoclinic needles (crystalized from alcohol and toluene) with a slight odor. Its molecular formula is C13H13N3 and its molecular weight is 211.26 g/mol. It boils at 170 °C, melts at 150 °C.

Under the GHS it carries the signal word Warning.

02 · Identifiers

Diphenylguanidine identifiers and molecular data

Diphenylguanidine CAS number and EC number

CAS number102-06-7
EC number203-002-1
Index number (CLP Annex VI)612-149-00-4

Diphenylguanidine molecular formula and molecular weight

Molecular formulaC13H13N3
Molecular weight211.26 g/mol

Other names for Diphenylguanidine

  • 1,3-diphenylguanidine

03 · GHS classification

Diphenylguanidine hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Diphenylguanidine pictograms and signal word

Signal wordWarning

Diphenylguanidine hazard class and category

GHS hazard classes Diphenylguanidine falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 4 H302 GHS07
Skin corrosion/irritation GHS chapter 3.2 Category 2 H315 GHS07
Serious eye damage/eye irritation GHS chapter 3.3 Category 2A H319 GHS07
Specific target organ toxicity - single exposure GHS chapter 3.8 Category 3 H335 GHS07
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 2 H411 GHS09

Diphenylguanidine hazard statements (H-codes)

Hazard statements assigned to Diphenylguanidine
CodeHazard statement
H361f Suspected of damaging fertility.
H302 Harmful if swallowed.
H335 May cause respiratory irritation.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H411 Toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Diphenylguanidine. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Diphenylguanidine

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Diphenylguanidine issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Diphenylguanidine precautionary statements

CLP Annex VI assigns 16 precautionary statements to Diphenylguanidine. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Diphenylguanidine name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български 1,3-дифенилгуанидин
Spanish español 1,3-Difenilguanidina
Czech čeština 1,3-difenylguanidin
Danish dansk 1,3-diphenylguanidin
German Deutsch 1,3-Diphenylguanidin
Estonian eesti 1,3-difenüülguanidiin
Greek ελληνικά 1,3-διφαινυλογουανιδίνη
English English 1,3-diphenylguanidine
French français 1,3-diphénylguanidine
Croatian hrvatski 1,3-difenilgvanidin
Italian italiano 1,3-difenilguanidina
Latvian latviešu 1,3-difenilguanidīns
Lithuanian lietuvių 1,3-difenilguanidinas
Hungarian magyar 1,3-difenilguanidin
Maltese Malti 1,3-difenilgwanidina
Dutch Nederlands 1,3-difenylguanidine
Polish polski 1,3-difenyloguanidyna
Portuguese português 1,3-difenilguanidina
Romanian română 1,3-difenilguanidină
Slovak slovenčina 1,3-difenylguanidín
Slovenian slovenščina 1,3-difenilgvanidin
Finnish suomi 1,3-difenyyliguanidiini
Swedish svenska 1,3-difenylguanidin

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Diphenylguanidine GHS label elements

Everything CLP Annex VI fixes for Diphenylguanidine, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS08 Health hazard pictogramGHS07 Exclamation mark pictogramGHS09 Environment pictogram

Warning

Diphenylguanidine

  • Suspected of damaging fertility.
  • Harmful if swallowed.
  • May cause respiratory irritation.
  • Causes skin irritation.
  • Causes serious eye irritation.
  • Toxic to aquatic life with long lasting effects.
  • Wash thoroughly after handling.
  • Do not eat, drink or smoke when using this product.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • IF IN EYES:
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Get medical advice/attention.
  • Rinse mouth.
  • If skin irritation occurs:
  • If eye irritation persists:
  • Remove contact lenses, if present and easy to do. Continue rinsing.
  • Wash with plenty of water/
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Diphenylguanidine in the GHS label constructor →

07 · Health hazards

Diphenylguanidine health hazards and exposure limits

Diphenylguanidine hazard summary

A mild eye irritant; May affect human reproduction, based on animal studies; [ICSC] Based on animal studies, a mild eye irritant, but not a skin irritant; Metabolized quickly and eliminated in urine and feces; Has effects on liver and nervous system in feeding studies; Not genotoxic; Not teratogenic; Fetotoxic at maternotoxic doses; [Reference #2]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Physical and chemical properties

Diphenylguanidine properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Diphenylguanidine boiling point

Property Value Conditions Source
Boiling point 170 °C (338 °F) above this value CAMEO
170 °C (338 °F) decomposes, decomposes HSDB

Diphenylguanidine melting point

Property Value Conditions Source
Melting point 150 °C (302 °F) HSDB

Diphenylguanidine density

Property Value Conditions Source
Density 1.19 g/cm³ ICSC
1.13 g/cm³ at 20 °C HSDB

Diphenylguanidine solubility

Property Value Conditions Source
Solubility Soluble in ethanol, carbon tetrachloride, chloroform, toluene; very soluble in ethyl ether. HSDB
less than 1 mg/mL at 70 °F (NTP, 1992) at 21.11 °C CAMEO
In water, 1,000 mg/L at 25 °C at 25 °C HSDB

Diphenylguanidine vapor pressure

Property Value Conditions Source
Vapor pressure 1.2751 mmHg at 20 °C ICSC
0.000004 mmHg at 25 °C HSDB
0.00000845 mmHg Haz-Map

Diphenylguanidine flash point

Property Value Conditions Source
Flash point 197.78 °C (388 °F) CAMEO
170 °C (338 °F) ICSC

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

Diphenylguanidine storage and handling

Diphenylguanidine safe storage

Separated from food and feedstuffs.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Diphenylguanidine reactivity

1,3-DIPHENYLGUANIDINE behaves as an amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. This chemical is incompatible with strong oxidizers. (NTP, 1992)

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Diphenylguanidine in the storage compatibility matrix →

10 · Questions

Diphenylguanidine — frequently asked questions

What is the CAS number of Diphenylguanidine?

The CAS number of Diphenylguanidine is 102-06-7. Its EC number is 203-002-1.

What is the chemical formula of Diphenylguanidine?

The molecular formula of Diphenylguanidine is C13H13N3 and its molecular weight is 211.26 g/mol.

What does a Diphenylguanidine label have to show?

Under CLP Annex VI the label for Diphenylguanidine carries the pictograms Health hazard, Exclamation mark and Environment and the signal word is Warning.

Is Diphenylguanidine flammable?

CLP Annex VI assigns Diphenylguanidine no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 197.78 °C (388 °F) (CAMEO).

Is Diphenylguanidine a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Diphenylguanidine. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of Diphenylguanidine?

The boiling point reported for Diphenylguanidine is 170 °C (338 °F), above this value (CAMEO).

What is the melting point of Diphenylguanidine?

The melting point reported for Diphenylguanidine is 150 °C (302 °F) (HSDB).

Get the free GHS / CLP / OSHA deadline calendar

Verified 2026–2029 compliance dates in one PDF — plus alerts when the rules change.